WordNet
- travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
- the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
- proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
- create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
- carry on or function; "We could do with a little more help around here" (同)manage
- get (something) done; "I did my job" (同)perform
- treat with an agent; add (an agent) to; "The ray dosed the paint"
- the quantity of an active agent (substance or radiation) taken in or absorbed at any one time (同)dosage
- a measured portion of medicine taken at any one time (同)dosage
- the top or extreme point of something (usually a mountain or hill); "the view from the peak was magnificent"; "they clambered to the tip of Monadnock"; "the region is a few molecules wide at the summit" (同)crown, crest, top, tip, summit
- a leguminous plant of the genus Pisum with small white flowers and long green pods containing edible green seeds (同)pea plant
- the fruit or seed of a pea plant
- seed of a pea plant used for food
- having or rising to a peak; "the peaked ceiling"; "the islands peaked hills"
PrepTutorEJDIC
- 《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
- ド(全音階の第1音)
- (おもに飲み薬1回分の)『服用量』 / (痛いこと・いやなことの)1回分,一定量 / (人などが受ける放射線の)線量 / 性病 / (…を)…‘に'投薬する,服用させる《+『名』+『with』+『名』》
- (とがった)『山頂』,峰;最も高い所 / (独立した)鋭峰,孤峰 / 『とがった先』,先端 / (事の)最頂点,絶頂,ピーク / (帽子の)前びさし / 最高の,最大の,ピークの / 頂点に達する,最高(最大)になる
- 《古》〈勢いが〉衰える;〈人が〉病み衰える,やつれる
- 『エンドウ』;エンドウ豆
- 先のとがった;前びさしのある
- やせた,やつれた
UpToDate Contents
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English Journal
- Striatal mRNA expression patterns underlying peak dose l-DOPA-induced dyskinesia in the 6-OHDA hemiparkinsonian rat.
- Smith LM1, Parr-Brownlie LC2, Duncan EJ3, Black MA4, Gemmell NJ5, Dearden PK3, Reynolds JN2.
- Neuroscience.Neuroscience.2016 Jun 2;324:238-51. doi: 10.1016/j.neuroscience.2016.03.012. Epub 2016 Mar 8.
- l-DOPA is the primary pharmacological treatment for relief of the motor symptoms of Parkinson's disease (PD). With prolonged treatment (⩾5years) the majority of patients will develop abnormal involuntary movements as a result of l-DOPA treatment, known as l-DOPA-induced dyskinesia. Understanding t
- PMID 26968766
- A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson's Disease.
- Tison F1,2,3,4, Keywood C5, Wakefield M5, Durif F4,6, Corvol JC4,7, Eggert K8, Lew M9, Isaacson S10, Bezard E1,2, Poli SM5, Goetz CG11, Trenkwalder C12, Rascol O4,13.
- Movement disorders : official journal of the Movement Disorder Society.Mov Disord.2016 May 23. doi: 10.1002/mds.26659. [Epub ahead of print]
- BACKGROUND: The metabotropic glutamate receptor 5-negative allosteric modulator dipraglurant reduces levodopa-induced dyskinesia in the MPTP-macaque model. The objective of this study was to assess the safety, tolerability (primary objective), and efficacy (secondary objective) of dipraglurant on le
- PMID 27214664
Japanese Journal
- Direct Relief of Levodopa-Induced Dyskinesia by Stimulation in the Area Above the Subthalamic Nucleus in a Patient With Parkinson's Disease : Case Report
- , , , , , , ,
- Neurologia medico-chirurgica = 神経外科 50(3), 257-259, 2010-03-15
- … A 71-year-old woman with a 25-year history of levodopa (LD)-responsive Parkinson's disease (PD) developed on-off motor fluctuation and severe peak dose dyskinesia. … STN-DBS induced attenuation of her cardinal PD symptoms and marked improvement of dyskinesia without reduction of LD dosage perioperatively. … LD-induced dyskinesia can also be controlled via reduction of LD dosage as an indirect effect of STN-DBS. …
- NAID 10025950896
Related Links
- 以下はあるブログ記事からの引用です。 ジスキネジアについてわかりやすく説明してあります。 パーキンソン病におけるdrug-induced dyskinesiaについて.Peak dose dyskinesia,diphasic dyskinesia ...
- ジスキネジア (厚生労働省) 英語名: Dyskinesia, Tardive dyskinesia ジスキネジアとは、 自分では止めらない・または止めてもすぐに出現する 下記のようなおかしな動きをまとめた呼び名で、このような症状は ...
★リンクテーブル★
[★]
- 関
- carry out、conduct、execute、make、perform、practice、undertake
[★]
- 関
- dosage、ID、injected dose、input
[★]
- 関
- administration、medicate、prescription
[★]
- 関
- Pisum sativum
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