adj.

発作性の

関: ictal, paroxystic, paroxysm

WordNet

accompanied by or of the nature of paroxysms
of or relating to a seizure or convulsion (同)ictic
abasia related to spasticity of the legs
a sudden uncontrollable attack; "a paroxysm of giggling"; "a fit of coughing"; "convulsions of laughter" (同)fit, convulsion

PrepTutorEJDIC

(病気の周期的な)発作《+『of』+『名』》 / (感情・行動などの)激発,発作的行動《+『of』+『名』》

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/03/10 10:54:16」(JST)

wiki en

[Wiki en表示]

"Paroxysms" redirects here. For the waltz by Johann Strauss, see Paroxysmen.

Not to be confused with proximal.

Paroxysmal attacks or paroxysms are a sudden recurrence or intensification of symptoms, such as a spasm or seizure.^[1] These short, frequent and stereotyped symptoms can be observed in various clinical conditions. They are usually associated with multiple sclerosis or pertussis, but they may also be observed in other disorders such as encephalitis, head trauma, stroke, asthma, trigeminal neuralgia, breath-holding spells, epilepsy, malaria, tabes dorsalis, and Behçet's disease, paroxysmal nocturnal hemoglobinuria (PNH). It has also been noted as a symptom of gratification disorder in children.

Paroxysmal attacks in various disorders have been reported extensively and ephaptic coupling of demyelinated nerves has been presumed as one of the underlying mechanisms of this phenomenon. This is supported by the presence of these attacks in multiple sclerosis and tabes dorsalis, which both involve demyelination of spinal cord neurons. Exercise, tactile stimuli, hot water, anxiety and neck flexion may provoke paroxysmal attacks. Most reported paroxysmal attacks are painful tonic spasms, dysarthria and ataxia, numbness and hemiparesis. They are typically different from other transient symptoms by their brevity (lasting no more than 2 minutes), frequency (from 1-2 times/day up to a few hundred times/day), stereotyped fashion and excellent response to drugs (usually carbamazepine). Withdrawal of symptoms without any residual neurological finding is another key feature in their recognition.

The word paroxysm means "sudden attack, outburst",^[2] and comes from the Greek παροξυσμός (paroxusmos), "irritation, exasperation".^[3]

References[edit]

^ Saunders Elsevier, "Dorland's Illustrated Medical Dictionary 31e", Philadelphia (2007), p1405, ISBN 978-1-4160-2364-7
^ paroxysm, on Oxford Dictionaries
^ παροξυσμός, Henry George Liddell, Robert Scott, A Greek-English Lexicon, on Perseus

UpToDate Contents

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1. 発作性心房細動 paroxysmal atrial fibrillation
2. 発作性夜間血色素尿症の診断および治療 diagnosis and treatment of paroxysmal nocturnal hemoglobinuria
3. 小児における非てんかん性発作性疾患 nonepileptic paroxysmal disorders in children
4. 幼児における非てんかん性発作性障害 nonepileptic paroxysmal disorders in infancy
5. 発作性片側頭痛：臨床的特徴および診断 paroxysmal hemicrania clinical features and diagnosis

English Journal

Episodic movement disorders: from phenotype to genotype and back.

Brockmann K.SourceInterdisciplinary Pediatric Center for Children with Developmental Disabilities and Severe Chronic Disorders, University Medical Center, Georg August University Göttingen, Robert Koch Str. 40, 37075, Göttingen, Germany, kbrock@med.uni-goettingen.de.
Current neurology and neuroscience reports.Curr Neurol Neurosci Rep.2013 Oct;13(10):379. doi: 10.1007/s11910-013-0379-7.
Episodic dyskinetic movement disorders are a heterogeneous group of rare conditions. Paroxysmal dyskinesias constitute the core of this group and usually exhibit normal interepisodic neurologic findings. Contrariwise, episodic dyskinesias occur as a particular feature of complex chronic neurologic d
PMID 23963607

Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures.

Iori V, Maroso M, Rizzi M, Iyer AM, Vertemara R, Carli M, Agresti A, Antonelli A, Bianchi ME, Aronica E, Ravizza T, Vezzani A.SourceDepartment of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
Neurobiology of disease.Neurobiol Dis.2013 Oct;58:102-14. doi: 10.1016/j.nbd.2013.03.006. Epub 2013 Mar 21.
Toll-like receptor 4 (TLR4) activation in neuron and astrocytes by High Mobility Group Box 1 (HMGB1) protein is a key mechanism of seizure generation. HMGB1 also activates the Receptor for Advanced Glycation Endproducts (RAGE), but it was unknown whether RAGE activation contributes to seizures or to
PMID 23523633

Evaluation of vertebrobasilar artery changes in patients with benign paroxysmal positional vertigo.

Zhang D, Zhang S, Zhang H, Xu Y, Fu S, Yu M, Ji P.SourceaDepartment of Neurology, Zhengzhou People's Hospital bThird Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, China.
Neuroreport.Neuroreport.2013 Sep 11;24(13):741-5. doi: 10.1097/WNR.0b013e328364b948.
The aim of this study was to investigate vertebrobasilar artery (VBA) lesions in elderly patients with benign paroxysmal positional vertigo (BPPV) by magnetic resonance angiography. VBA lesions in patients older than 65 years of age with BPPV were prospectively investigated by magnetic resonance ang
PMID 23903461

Japanese Journal

ESUS (embolic stroke of undetermined sources) (特集脳卒中 : 新時代の治療を求めて) -- (臨床上の課題)

日本臨床 74(4), 597-602, 2016-04
NAID 40020775887

発作性心房細動アブレーション : バルーンカテーテルによる新時代アブレーション (第1土曜特集不整脈を科学する) -- (心房細動を識る・治す)

医学のあゆみ 256(6), 749-754, 2016-02-06
NAID 40020723913

発作性夜間ヘモグロビン尿症合併妊娠の管理上の注意点

血液内科 = Hematology 72(2), 266-271, 2016-02
NAID 40020749826

「ictal」

Paroxysmal attack
	Classification and external resources
ICD-10	G40-G47

　　[★]

adj.

発作性の、てんかん発作の

関: epileptic insult、epileptic seizure、epileptogenesis、epileptogenic、paroxysmal、paroxystic、seizure

「paroxystic」

　　[★]

adj.

発作性の

関: ictal、paroxysmal

「発作性」

　　[★]

英

paroxysmal、ictal、paroxystic

「chronic paroxysmal hemicrania」

　　[★]

慢性発作性片側頭痛

関: paroxysmal hemicrania

「paroxysmal nerve pain」

　　[★]

発作性神経痛

関: nerve pain、neuralgia

「paroxysmal nocturnal hemoglobinuria」

　　[★] 発作性夜間血色素尿症 PNH

「benign paroxysmal vertigo in childhood」

　　[★] 小児期良性発作性眩暈症

「paroxysm」

　　[★]

n.

(医)(寒気などの周期的な)発作。(医)痙攣。激発。発作的活動、激動

関: (adj.)paroxysmal
関: attack、bout、crises、crisis、insult、seizure、stroke

[1] Saunders Elsevier, "Dorland's Illustrated Medical Dictionary 31e", Philadelphia (2007), p1405, ISBN 978-1-4160-2364-7

[2] roxysm, on Oxford Dictionaries

[3] παροξυσμός, Henry George Liddell, Robert Scott, A Greek-English Lexicon, on Perseus

リンク元	「ictal」「paroxystic」「発作性」
拡張検索	「chronic paroxysmal hemicrania」「paroxysmal nerve pain」「paroxysmal nocturnal hemoglobinuria」「benign paroxysmal vertigo in childhood」
関連記事	「paroxysm」

匿名

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案内

案内

paroxysmal