WordNet

without undue constriction as from e.g. tenseness or inhibition; "the clarity and resonance of an open tone"; "her natural and open response"
a clear or unobstructed space or expanse of land or water; "finally broke out of the forest into the open" (同)clear
information that has become public; "all the reports were out in the open"; "the facts had been brought to the surface" (同)surface
a tournament in which both professionals and amateurs may play
become available; "an opportunity opened up" (同)open_up
become open; "The door opened" (同)open_up
cause to open or to become open; "Mary opened the car door" (同)open_up
make available; "This opens up new possibilities" (同)open_up
start to operate or function or cause to start operating or functioning; "open a business" (同)open_up
not sealed or having been unsealed; "the letter was already open"; "the opened package lay on the table" (同)opened
used of mouth or eyes; "keep your eyes open"; "his mouth slightly opened" (同)opened
not brought to a conclusion; subject to further thought; "an open question"; "our position on this bill is still undecided"; "our lawsuit is still undetermined" (同)undecided, undetermined, unresolved
affording unobstructed entrance and exit; not shut or closed; "an open door"; "they left the door open" (同)unfastened
(set theory) of an interval that contains neither of its endpoints
accessible to all; "open season"; "an open economy"
affording free passage or access; "open drains"; "the road is open to traffic"; "open ranks"
begin or set in action, of meetings, speeches, recitals, etc.; "He opened the meeting with a long speech"
display the contents of a file or start an application as on a computer
have an opening or passage or outlet; "The bedrooms open into the hall"
having no protecting cover or enclosure; "an open boat"; "an open fire"; "open sports cars"
make the opening move; "Kasparov opened with a standard opening"
not having been filled; "the job is still open"
not requiring union membership; "an open shop employs nonunion workers"
open to or in view of all; "an open protest"; "an open letter to the editor"
ready for business; "the stores are open"
first or beginning; "the memorable opening bars of Beethovens Fifth"; "the plays opening scene"
opportunity especially for employment or promotion; "there is an opening in the sales department"
a recognized sequence of moves at the beginning of a game of chess; "he memorized all the important chess openings" (同)chess opening
a vacant or unobstructed space that is man-made; "they left a small opening for the cat at the bottom of the door"
becoming open or being made open; "the opening of his arms was the sign I was waiting for"
the act of opening something; "the ray of light revealed his cautious opening of the door"
an open or empty space in or between things; "there was a small opening between the trees"; "the explosion made a gap in the wall" (同)gap
the first performance (as of a theatrical production); "the opening received good critical reviews" (同)opening_night, curtain raising
a ceremony accompanying the start of some enterprise
the initial part of the introduction; "the opening established the basic theme"
distinguish (as a compound or molecule) by introducing a labeled atom
a radioactive isotope that is used in a compound in order to trace the mechanism of a chemical reaction
trade name of a company that produces musical recordings; "the artists and repertoire department of a recording label is responsible for finding new talent" (同)recording label
a brief description given for purposes of identification; "the label Modern is applied to many different kinds of architecture"
an identifying or descriptive marker that is attached to an object
assign a label to; designate with a label; "These students were labelled `learning disabled"
distinguish (an element or atom) by using a radioactive isotope or an isotope of unusual mass for tracing through chemical reactions
a workplace for the conduct of scientific research (同)laboratory, research lab, research laboratory, science lab, science laboratory
bearing or marked with a label or tag; "properly labeled luggage" (同)labelled, tagged

PrepTutorEJDIC

…‘を'『開く』,開ける;…‘の'ふた(おおい)をとる / …‘を'『切り開いて作る』,開拓する;…‘を'全開通させる《+『名』+『up,』+『名』+『up』》 / …‘を'『広げる』《+『up』+(『out』)+『名,』+『名』+『up』(『out』)》 / …‘を'『始める』 / …‘を'開業する,開店する,開場する / (人に)〈心など〉‘を'打ち明ける,〈秘密など〉‘を'漏らす《+『名』+『to』+『名』》 / (新思想などに)〈心・目〉‘を'開く《+『名』+『to』+『名』》 / 〈戸などが〉『開く』,あく / 〈花・つぼみが〉開く《+『out』》 / 〈学校などが〉『始まる』;〈店などが〉開く / 〈道路などが〉開通する / (…に)向かって開いている,(…に)通じている《+『out』『on』(『upon,to,onto』)+『名』》 / 《副詞[句]を伴って》〈風景などが〉広がる,ひらける / 本を開く;(…)ページを開く《+『to』(《英》『at』)+『名』》 / (窓・口などが)『開いた』,開いている;(包みなどが)広げられて / (花が)咲いた / (店などが)『開いている』,開業している;(催し物が)『公開の』,だれでも入れる / 《名詞の前にのみ用いて》ふたのしてない,屋根のない,おおいのない / 広く開いた,さえぎるものがない / 公然の / 率直な,遠慮しない / さらされている,無防備の / 《補語にのみ用いて》(職・地位などが)空位の;(時間などが)あいている / (問題・議事などが)未解決の / 凍結しない,雪や霜の降らない;温和な / (漁・猟が)解禁の / (音声が)開口音の;開音節の / 《the~》戸外,野外 / 空き地;(樹木のない)開けた場所,平野
〈C〉(森・垣根・壁などの)空いている所;空き地;すき間,穴 / 〈C〉(物語・会議などの)始め,出だし,冒頭(beginning) / 〈C〉(…の地位の)空き,就職口《+『for』(『at, in』)+『名』》(vacant) / 〈C〉(劇などの)初演 / 〈U〉(…が)開くこと,あくこと《+『of』+『名』》 / 〈C〉(…の)よい機会,好機《+『for』+『名』》 / 初めの,開始の
(品名・製造元などを示す)『はり札』,ラベル;(小包などの)荷札 / (団体・運動・政党支持者などの特徴を示す)短い文句,通り名;(辞書の見出し語などにつける)ラベル([物理][化学]など) / …‘に'『ラベルをはる』,荷札をつける;《比喩(ひゆ)的》〈人〉‘に'レッテルをはる
実験室(laboratory)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/28 10:06:16」(JST)

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[Wiki en表示]

An open-label trial or open trial is a type of clinical trial in which both the researchers and participants know which treatment is being administered.^[1]^[2] This contrasts with single blind and double blind experimental designs, where participants are not aware of what treatment they are receiving (researchers are also unaware in a double blind trial).

Open-label trials may be appropriate for comparing two very similar treatments to determine which is most effective. An open-label trial may be unavoidable under some circumstances, such as comparing the effectiveness of a medication to intensive physical therapy sessions.

An open-label trial may still be randomized. Open-label trials may also be uncontrolled, with all participants receiving the same treatment.

References

^ "Definition: open-label trial from Online Medical Dictionary".
^ "Open label study entry in the public domain NCI Dictionary of Cancer Terms".

This medical article is a stub. You can help Wikipedia by expanding it.

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English Journal

Changes in Clinical Management and Diagnosis following DaTscan™ SPECT Imaging in Patients with Clinically Uncertain Parkinsonian Syndromes: A 12-Week Follow-Up Study.

Kupsch A, Bajaj N, Weiland F, Tartaglione A, Klutmann S, Copp R, Sherwin P, Tate A, Grachev ID.SourceDepartment of Neurology, Charité Campus Virchow-Kinikum, University Medicine Berlin, Berlin, Germany.
Neuro-degenerative diseases.Neurodegener Dis.2013;11(1):22-32. Epub 2012 May 8.
Background: An accurate diagnosis is important for timely and adequate treatment in patients with clinically uncertain parkinsonian syndrome (CUPS). Objective: The objective of this study was to assess safety and changes in clinical management, diagnosis and quality of life (QoL) at 4 and 12 weeks f
PMID 22571977

Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia.

Na KS, Kim WH, Jung HY, Ryu SG, Min KJ, Park KC, Kim YS, Yoon JS, Ahn YM, Kim CE.SourceDepartment of Psychiatry, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2012 Dec 3;39(2):295-300. doi: 10.1016/j.pnpbp.2012.06.024. Epub 2012 Jul 11.
OBJECTIVE: Metabolic syndrome and antipsychotic medications are associated with inflammation. This study investigated the relationship between inflammation and metabolic syndrome in patients with schizophrenia. It also examined the effects of paliperidone extended release (ER) treatment on metabolic
PMID 22796278

Japanese Journal

Safety and Efficacy of the Oral Direct Factor Xa Inhibitor Apixaban in Japanese Patients With Non-Valvular Atrial Fibrillation : The ARISTOTLE-J Study

OGAWA Satoshi,SHINOHARA Yukito,KANMURI Kazuhiro
Circulation journal : official journal of the Japanese Circulation Society 75(8), 1852-1859, 2011-07-25
… or open-label warfarin (target international normalized ratio 2.0-3.0; …
NAID 10029127696

An open-label, single-arm study assessing the efficacy and safety of L-menthol sprayed onto the gastric mucosa during upper gastrointestinal endoscopy

HIKI Naoki,KAMINISHI Michio,TANABE Satoshi,FUJISAKI Junko,YOSHINO Junji,IGUCHI Mikitaka,KOBAYASHI Hiroyuki,ASHIDA Kiyoshi,KAWABE Takao,KAWANO Tatsuyuki,NOMURA Sachiyo,YAHAGI Naohisa,TAJIRI Hisao,SUZUKI Hiroaki
Journal of gastroenterology 46(7), 873-882, 2011-07-01
NAID 10029313145