関: v-Ha-ras

WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
the 8th letter of the Roman alphabet (同)h
the 22nd letter of the Roman alphabet (同)v

PrepTutorEJDIC

蛋白(たんばく)質
hydrogenの化学記号
鉛筆の硬度 / 《俗》heroin
vanadium の化学記号
おや,はああ,ああ(驚き・喜び・疑い・ためらいなどを表す声)
hectare; hectares

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1. 小児の褐色細胞腫と傍神経節腫pheochromocytoma and paraganglioma in children [show details]
… The erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) may be elevated,… Multiple endocrine neoplasia type 2A or 2B (MEN2) – Associated with mutations in the RET proto-oncogene. Approximately 50 percent of cases of MEN2 include pheochromocytoma . Neurofibromatosis type … features suggestive of secondary hypertension, after exclusion of other causes, especially renovascular disease. Hypertension in association with other symptoms of sympathetic overactivity, such as episodic …
2. 神経線維腫症I型（NF1）：病因、臨床的特徴、および診断neurofibromatosis type 1 nf1 pathogenesis clinical features and diagnosis [show details]
… hydrolase (GTPase)-activating proteins (GAPs) that stimulate intrinsic GTPase activity in the ras p21 family (21 kD rat sarcoma viral oncogene homologs) .… producing renovascular hypertension are more frequent in NF1 patients. Thus, evaluation for renal artery stenosis should be initiated in children with NF1 and hypertension . Renovascular lesions…
3. 褐色細胞腫の臨床症状および診断clinical presentation and diagnosis of pheochromocytoma [show details]
… genes encoding proteins that function in the cellular response to hypoxia; and cluster 2, genes encoding proteins that activate kinase signaling… hyperadrenergic spells, labile primary hypertension (formerly called "essential" hypertension), renovascular disease, hypoglycemia, postural orthostatic tachycardia syndrome (POTS), mast cell disease, and carcinoid … mutations in the VHL tumor suppressor gene. MEN2, which is associated with mutations in the RET proto-oncogene. Pheochromocytoma is also seen, albeit less commonly, albeit rarely, with neurofibromatosis…
4. 神経線維腫症I型（NF1）：マネージメントおよび予後neurofibromatosis type 1 nf1 management and prognosis [show details]
… although the use of mitogen-activated protein kinase kinase (MAPKK or MEK) inhibitors is changing the… in the v-Kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologue (KIT) or platelet-derived growth factor receptor,… significantly increased risk of renovascular hypertension, particularly due to renal artery stenosis in younger adults.…
5. 微細欠失症候群（1番～11番染色体）microdeletion syndromes chromosomes 1 to 11 [show details]
… ETS proto-oncogene 1 transcription factor (ETS1), Fli-1 proto-oncogene ETS transcription factor (FLI1), nuclear factor related to kappa B binding protein (NFRKB),… include supravalvular aortic stenosis (in 70 percent of cases), pulmonic valve stenosis, and renal artery stenosis. Renal abnormalities are also seen. Other clinical features include constipation, which …

English Journal

ERBB4 is over-expressed in human colon cancer and enhances cellular transformation.

Williams CS1, Bernard JK2, Demory Beckler M2, Almohazey D3, Washington MK4, Smith JJ5, Frey MR6.
Carcinogenesis.Carcinogenesis.2015 Jul;36(7):710-8. doi: 10.1093/carcin/bgv049. Epub 2015 Apr 27.
PMID 25916654

Papillary thyroid microcarcinoma with fatal outcome: evidence of tumor progression in lymph node metastases: report of 3 cases, with morphological and molecular analysis.

Piana S1, Ragazzi M, Tallini G, de Biase D, Ciarrocchi A, Frasoldati A, Rosai J.
Human pathology.Hum Pathol.2013 Apr;44(4):556-65. doi: 10.1016/j.humpath.2012.06.019. Epub 2012 Oct 15.
PMID 23079204

Differential inhibitory effects of two Raf-targeting drugs, sorafenib and PLX4720, on the growth of multidrug-resistant cells.

Eum KH1, Ahn SK, Kang H, Lee M.
Molecular and cellular biochemistry.Mol Cell Biochem.2013 Jan;372(1-2):65-74. doi: 10.1007/s11010-012-1446-0. Epub 2012 Sep 2.
PMID 22941213