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1. 内皮：プライマーthe endothelium a primer [show details]
… Endothelial cells express a range of complement receptors and complement regulatory proteins, and are subject to attack by complement . The C5b-9 membrane attack complex (MAC) can induce endothelial cell lysis …
2. 敗血症や敗血症性ショックの疑いのある成人の評価とマネージメントevaluation and management of suspected sepsis and septic shock in adults [show details]
… There was a heavy emphasis on the use of red cell transfusion (for a hematocrit >30) and dobutamine to reach the ScvO₂ target in this trial.… The choice of antimicrobials can be complex and should consider the patient history (eg,… norepinephrine versus vasopressin , norepinephrine versus terlipressin , norepinephrine versus epinephrine ,…
3. アナフィラキシーの病態生理pathophysiology of anaphylaxis [show details]
… mast cells and/or basophils. The events leading to allergen-specific IgE production in an atopic individual are complex. In brief, B cells are driven to differentiate into IgE-producing cells via… cardiovascular responses to norepinephrine, although this has not been studied in human anaphylaxis . Murine models suggest H4 receptors might be involved in chemotaxis and mast cell cytokine release,…
4. 慢性非癌性疼痛治療の概要overview of the treatment of chronic non cancer pain [show details]
… stimulator placement is chronic pain from failed back surgery syndrome. SCS may also be used for complex regional pain syndrome, intractable angina, and painful peripheral vascular disease. Although … agonists; Antidepressants (tricyclics and serotonin-norepinephrine reuptake inhibitors [SNRIs]) Antiepileptic drugs (gabapentin,…
5. セロトニン再取り込み阻害剤（SSRI）およびセロトニン・ノルアドレナリン再取り込み阻害薬（SNRI）への出生前曝露があった乳児や小児：発育、運動能力、認知機能に異常が生じるリスクinfants and children with antenatal exposure to selective serotonin reuptake inhibitors ssris and serotonin norepinephrine reuptake inhibitors snris risk of abnormalities in growth motor skills and cognition [show details]
…inhibitors and serotonin-norepinephrine reuptake inhibitors is limited due to several factors. The teratogenicity of selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors …

English Journal

Noradrenaline depresses spontaneous complex spikes activity of cerebellar Purkinje cells via α2-adrenergic receptor in vivo in mice.

Sun N, Li BX, Hong YJ, Bing YH, Qiu DL, Chu CP.
Neuroscience letters. 2019 Jun;703()38-44.
Locus coeruleus (LC) noradrenergic neurons afferents release noradrenaline (NA) in the cerebellar cortex for modulating cerebellar neuronal circuitry function. Our previous study found that NA inhibited the spontaneous simple spikes activity of cerebellar Purkinje cells (PC) through activation of mo
PMID 30853408

A Review of Humoral Factors in Remote Preconditioning of the Heart.

Tsibulnikov SY, Maslov LN, Gorbunov AS, Voronkov NS, Boshchenko AA, Popov SV, Prokudina ES, Singh N, Downey JM.
Journal of cardiovascular pharmacology and therapeutics. 2019 Apr;()1074248419841632.
A humoral mechanism of cardioprotection by remote ischemic preconditioning (RIP) has been clearly demonstrated in various models of ischemia-reperfusion including upper and lower extremities, liver, and the mesenteric and renal arteries. A wide range of humoral factors for RIP have been proposed inc
PMID 31035796

Immunohistochemical analysis of the mouse celiac ganglion: An integrative relay station of the peripheral nervous system.

Kaestner CL, Smith EH, Peirce SG, Hoover DB.
The Journal of comparative neurology. 2019 Apr;().
Celiac ganglia are important sites of signal integration and transduction. Their complex neurochemical anatomy has been studied extensively in guinea pigs but not in mice. The goal of this study was to provide detailed neurochemical characterization of mouse celiac ganglia and noradrenergic nerves i
PMID 31021409

Japanese Journal

ニワトリ副腎のカテコラミン貯蔵細胞のレセルピン投与による変化の電子顕微鏡的研究〔英文〕

Chungsamarnyart Narong,藤岡俊健
日本獣医学雑誌 44(3), p439-457, 1982-06
ニワトリにレセルピンを投与し, その副腎髄質細胞の脱顆粒期およぴ顆粒再形成期の微細構造の変化を観察した. 4mg/kg のレセルピンを腹腔内に注射すると, 分泌顆粒の減少はアドレナリン貯蔵細胞 (A細胞) では注射後1時間で始まるのに対し, ノルアドレナリン貯蔵細胞 (NA細胞) では12時間後にみられる. 脱顆粒期には顆粒の内部構造の変化とともに顆粒の肥大が起こり, 顆粒が癒合して小さい空砲を形 …
NAID 110003917062

ニワトリ副腎のカテコラミン貯蔵細胞のレセルピン投与による変化の電子顕微鏡的研究

チユンサマンヤートナロン,藤岡俊健
日本獸醫學雜誌(The Japanese Journal of Veterinary Science) 44(3), 439-451,457, 1982
ニワトリにレセルピンを投与し, その副腎髄質細胞の脱顆粒期およぴ顆粒再形成期の微細構造の変化を観察した. 4mg/kg のレセルピンを腹腔内に注射すると, 分泌顆粒の減少はアドレナリン貯蔵細胞 (A細胞) では注射後1時間で始まるのに対し, ノルアドレナリン貯蔵細胞 (NA細胞) では12時間後にみられる. 脱顆粒期には顆粒の内部構造の変化とともに顆粒の肥大が起こり, 顆粒が癒合して小さい空砲を形 …
NAID 130003481297