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1. パーキンソン病の臨床症状clinical manifestations of parkinson disease [show details]
…patients with PD have cogwheel rigidity; many instead will have lead-pipe rigidity, a tonic resistance that is smooth throughout the entire range of passive movement. Rigidity can affect any part of the body …
2. スティッフパーソン症候群stiff person syndrome [show details]
…trunk is generally spared . The SLS is characterized by focal rigidity of one leg and differs from SPS in various ways : contractions and rigidity are limited to the affected extremity, it is rarely associated …
3. 成人における詳細な神経学的検査the detailed neurologic examination in adults [show details]
…the extensors of the lower extremity. Rigidity, in contrast to spasticity, is characterized by increased resistance throughout the movement. Lead-pipe rigidity applies to resistance that is uniform throughout …
4. 悪性症候群neuroleptic malignant syndrome [show details]
…is typical . Muscular rigidity is generalized and is often extreme. The increased tone can be demonstrated by moving the extremities and is characterized by "lead-pipe rigidity" or stable resistance through …
5. 大脳皮質基底核変性症corticobasal degeneration [show details]
…percent) Axial rigidity (27 and 69 percent) Tremor (20 and 39 percent) Limb dystonia (20 and 38 percent) Myoclonus (15 and 27 percent) In many cases, motor symptoms begin in one limb. Rigidity can be profound …

English Journal

Effect of Atropine on Adrenergic Responsiveness of Erythrocyte and Heart Rhythm Variability in Outbred Rats with Stimulation of the Central Neurotransmitter Systems.

Kur'yanova EV, Tryasuchev AV, Stupin VO, Teplyi DL.
Bulletin of experimental biology and medicine. 2018 Sep;165(5)597-601.
Single injection of muscarinic cholinoceptor blocker atropine (1 mg/kg) to outbred male rats reduced β-adrenergic responsiveness of erythrocytes (by 2.2 times) and the content of epinephrine granules on erythrocytes (by 1.5 times), significantly increased HR and rigidity of the heart rhythm, and ma
PMID 30225714

Effect of Stimulation of Neurotransmitter Systems on Heart Rate Variability and β-Adrenergic Responsiveness of Erythrocytes in Outbred Rats.

Kur'yanova EV, Tryasuchev AV, Stupin VO, Teplyi DL.
Bulletin of experimental biology and medicine. 2017 May;163(1)31-36.
We studied heart rate variability and β-adrenergic responsiveness of erythrocytes and changes in these parameters in response to single administration of β-adrenoblocker propranolol (2 mg/kg) in outbred male rats against the background of activation of the noradrenergic, serotonergic, and dopamine
PMID 28577106

Extrapyramidal effects of acute organophosphate poisoning.

Reji KK, Mathew V, Zachariah A, Patil AK, Hansdak SG, Ralph R, Peter JV.
Clinical toxicology (Philadelphia, Pa.). 2016 Mar;54(3)259-65.
There is limited information on extrapyramidal symptoms in acute organophosphate (OP) poisoning. We describe the course and outcome of severely poisoned patients who develop extrapyramidal manifestations. In this prospective observational study, spanning 8 months (Apr-Nov 2013) adult patients (>18
PMID 26735571