多施設治験

関: multicenter study、multicentre study、multicentre trial

WordNet

(law) the determination of a persons innocence or guilt by due process of law; "he had a fair trial and the jury found him guilty"; "most of these complaints are settled before they go to trial"
trying something to find out about it; "a sample for ten days free trial"; "a trial of progesterone failed to relieve the pain" (同)trial_run, test, tryout
an annoying or frustrating or catastrophic event; "his mother-in-laws visits were a great trial for him"; "life is full of tribulations"; "a visitation of the plague" (同)tribulation, visitation
(sports) a preliminary competition to determine qualifications; "the trials for the semifinals began yesterday"

PrepTutorEJDIC

〈U〉〈C〉『裁判』,公判,審理 / 〈U〉〈C〉(…の)『試験』,ためし《+of+名》 / 〈C〉企て,試み;努力 / 〈C〉(忍耐・徳・信仰などをためす)試練,苦難 / 〈C〉困りもの,迷惑な(やっかいな)人(もの)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/22 06:35:30」(JST)

wiki en

[Wiki en表示]

A multicenter research trial is a clinical trial conducted at more than one medical center or clinic. Most large clinical trials, particularly Phase III trials, are conducted at several clinical research centers.

Benefits

The benefits of multicenter trials include a larger number of participants, different geographic locations, the possibility of inclusion of a wider range of population groups, and the ability to compare results among centers, all of which increase the generalizability of the study. In many cases, efficacy will vary significantly between population groups with different genetic, environmental, and ethnic or cultural backgrounds ("demographic" factors); normally only geographically dispersed trials can properly evaluate this.

External links

ClinicalTrials.gov from US National Library of Medicine
Role of ICH GCP and Recruitment Strategies Training of Clinical Sites Staff in Successful Patient Recruitment Rates By Marithea Goberville, Ph.D.
IBPA Publications 2005

UpToDate Contents

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1. 黒色腫（メラノーマ）における所属リンパ節の評価および治療 evaluation and treatment of regional lymph nodes in melanoma
2. C型肝炎ウイルス感染に対する試験的治療 investigational therapies for hepatitis c virus infection
3. 重症患者における血糖コントロールおよび集中的なインスリン療法 glycemic control and intensive insulin therapy in critical illness
4. 高齢患者およびperformance statusのスコアが低い患者における進行非小細胞肺癌に対する全身療法 systemic therapy for advanced non small cell lung cancer in elderly patients and patients with a poor performance status
5. 収縮能障害による心不全におけるジゴキシンの使用 use of digoxin in heart failure due to systolic dysfunction

English Journal

Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial.

Gaul C1, Diener HC, Danesch U; Migravent® Study Group.
The journal of headache and pain.J Headache Pain.2015 Dec;16(1):516. doi: 10.1186/s10194-015-0516-6. Epub 2015 Apr 3.
BACKGROUND: Non-medical, non-pharmacological and pharmacological treatments are recommended for the prevention of migraine. The purpose of this randomized double-blind placebo controlled, multicenter trial was to evaluate the efficacy of a proprietary nutritional supplement containing a fixed combin
PMID 25916335

Psychometric properties of the glaucoma treatment compliance assessment tool in a multicenter trial.

Barker GT1, Cook PF2, Schmiege SJ2, Kahook MY3, Kammer JA4, Mansberger SL5.
American journal of ophthalmology.Am J Ophthalmol.2015 Jun;159(6):1092-1099.e2. doi: 10.1016/j.ajo.2015.03.006. Epub 2015 Mar 17.
PURPOSE: To assess the psychometric properties of a new version of the Glaucoma Treatment Compliance Assessment Tool, a survey evaluating health behavior and glaucoma adherence using constructs from the Health Belief Model.DESIGN: Psychometric analysis.METHODS: We administered the 47-statement Glauc
PMID 25794793

Novel dosing strategies increase exposures of the potent antituberculosis drug rifapentine but are poorly tolerated in healthy volunteers.

Dooley KE1, Savic RM2, Park JG3, Cramer Y3, Hafner R4, Hogg E5, Janik J6, Marzinke MA7, Patterson K8, Benson CA9, Hovind L6, Dorman SE7, Haas DW10; ACTG A5311 Study Team.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jun;59(6):3399-405. doi: 10.1128/AAC.05128-14. Epub 2015 Mar 30.
Rifapentine is a potent antituberculosis drug currently in phase III trials. Bioavailability decreases with increasing dose, yet high daily exposures are likely needed to improve efficacy and shorten the tuberculosis treatment duration. Further, the limits of tolerability are poorly defined. The pha
PMID 25824215

Japanese Journal

全身麻酔下における小児患者に対するレミフェンタニル塩酸塩の有効性及び安全性評価のための第Ⅲ相単群非盲検試験

麻酔と蘇生 52(2), 33-41, 2016-06-20
NAID 120005767030

Factors Influencing the Placebo Effect in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: An Analysis of Two Randomized Clinical Trials

PLOS ONE 11(6), 2016-06-02
NAID 120005838169

Sitagliptin monotherapy has better effect on insulinogenic index than glimepiride monotherapy in Japanese patients with type 2 diabetes mellitus: A 52-week, multicenter, parallel-group randomized controlled trial

Diabetology and Metabolic Syndrome 8, 2016-02-27
NAID 120005758426

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リンク元	「多施設治験」「multicenter study」「multicentre study」「multicentre trial」
関連記事	「trial」「multicenter」「tri」

「多施設治験」

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英: multicenter trial、multicenter study、multicentre trial、multicentre study

「multicenter study」

　　[★]

多施設治験

関: multicenter trial、multicentre study、multicentre trial

「multicentre study」

　　[★]

多施設治験

関: multicenter study、multicenter trial、multicentre trial

「multicentre trial」

　　[★]