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a malignant neoplasm of cartilage cells

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/25 17:30:44」(JST)

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Mesenchymal chondrosarcoma is a form of malignant chondrosarcoma.^[1]^[2] Unlike most chondrosarcomas, mesenchymal chondrosarcoma grows rapidly, tends to spread, and occurs more often in children and young adults than in older adults.^[3]

Type II collagen can help distinguish it from other tumors.^[4]

References

^ Hoang MP, Suarez PA, Donner LR, et al. (October 2000). "Mesenchymal Chondrosarcoma: A Small Cell Neoplasm with Polyphenotypic Differentiation". Int. J. Surg. Pathol. 8 (4): 291–301. doi:10.1177/106689690000800408. PMID 11494006.
^ Chen JY, Hsu SS, Ho JT (May 2004). "Extraskeletal intracranial mesenchymal chondrosarcoma: case report and literature review". Kaohsiung J. Med. Sci. 20 (5): 240–6. doi:10.1016/S1607-551X(09)70113-5. PMID 15233236. ^{[dead link]}
^ Goldberg, JM & Grier, H (December 2004). "Mesenchymal Chondrosarcoma". ESUN 1 (6).
^ Müller S, Söder S, Oliveira AM, Inwards CY, Aigner T (August 2005). "Type II collagen as specific marker for mesenchymal chondrosarcomas compared to other small cell sarcomas of the skeleton". Mod. Pathol. 18 (8): 1088–94. doi:10.1038/modpathol.3800391. PMID 15731776.

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1. 軟骨肉腫 chondrosarcoma
2. ユーイング肉腫ファミリーの腫瘍の疫学、病理、および分子遺伝学 epidemiology pathology and molecular genetics of the ewing sarcoma family of tumors
3. 頭蓋底の脊索腫および軟骨肉腫 chordoma and chondrosarcoma of the skull base
4. 頭頸部肉腫 head and neck sarcomas
5. 孤立性線維性腫瘍 solitary fibrous tumor

English Journal

SATB2 Expression Is Sensitive but Not Specific for Osteosarcomatous Components of Gynecologic Tract Carcinosarcomas: A Clinicopathologic Study of 60 Cases.

Sangoi AR1, Kshirsagar M, Horvai AE, Roma AA.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.Int J Gynecol Pathol.2016 Jun 10. [Epub ahead of print]
The novel marker special AT-rich sequence binding protein (SATB2) is highly sensitive for mesenchymal tumors with osteoblastic differentiation. However, SATB2 expression in gynecologic tract carcinosarcoma has not been previously explored. Given the potential prognostic and therapeutic implications
PMID 27294605

Primary Cilia and Intraflagellar Transport Proteins in Bone and Cartilage.

Yuan X1, Yang S2.
Journal of dental research.J Dent Res.2016 Jun 1. pii: 0022034516652383. [Epub ahead of print]
Primary cilia, present on most mammalian cells, function as a sensor to sense the environment change and transduce signaling. Loss of primary cilia causes a group of human pleiotropic syndromes called Ciliopathies. Some of the ciliopathies display skeletal dysplasias, implying the important role of
PMID 27250654

Primary synovial chondromatosis: a reassessment of malignant potential in 155 cases.

McCarthy C1, Anderson WJ1, Vlychou M1, Inagaki Y1, Whitwell D1, Gibbons CL1, Athanasou NA2.
Skeletal radiology.Skeletal Radiol.2016 Jun;45(6):755-62. doi: 10.1007/s00256-016-2353-3. Epub 2016 Feb 27.
OBJECTIVE: Primary synovial chondromatosis (PSC) is a rare disorder characterised by cartilage formation in synovium-lined joints, tendon sheaths and bursae. It is thought that PSC cartilage arises from the proliferation of mesenchymal cells, which exhibit cartilaginous metaplasia in subintimal conn
PMID 26919862