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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/21 20:49:04」(JST)

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Renal corpuscle. The entire structure is the renal corpuscle. The blue structure (A) is the Bowman's capsule (2 and 3). The pink structure is the glomerulus with its capillaries. At the left, blood flows from the afferent areteriole (9), through the capillaries (10), and out the efferent arteriole (11). The mesangium is the pink structure inside the glomerulus between the capillaries (5a) and extending outside the glomerulus (5b).

In the glomerulus of the kidney, the mesangium is a structure associated with the capillaries. It is continuous with the smooth muscles of the arterioles. It is outside the capillary lumen, but surrounded by capillaries. It is in the middle (meso) between the capillaries (angis). It is contained by the basement membrane, which surrounds both the capillaries and the mesangium.

This term is often used interchangeably with mesangial cell, but in this context refers specifically to the intraglomerular mesangial cells. These cells are phagocytic and secrete the amorphous basement membrane-like material known as the mesangial matrix. They are typically separated from the lumen of the capillaries by endothelial cells.

External links[edit]

Mesangium at eMedicine Dictionary
Physiology at MCG 7/7ch03/7ch03p12
"Mesangium" at Dorland's Medical Dictionary

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UpToDate Contents

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1. Chapter 2A：糸球体の解剖学的構造および機能 chapter 2a glomerular anatomy and function
2. 糸球体の免疫障害の機序 mechanisms of immune injury of the glomerulus
3. 腎アミロイドーシス renal amyloidosis
4. 成人におけるブドウ球菌随伴糸球体腎炎 staphylococcus associated glomerulonephritis in adults
5. IgA腎症の病因 pathogenesis of iga nephropathy

English Journal

Experimental comparison of protective characteristics of enalapril and trimetazidine in diabetic nephropathy.

Karadeniz T1, Cavusoğlu T, Turkmen E, Uyanıkgil Y, Karadeniz M, Akdemir O, Tuglu MI, Ates U, Erbas O.
Renal failure.Ren Fail.2014 Jul 10:1-8. [Epub ahead of print]
Abstract Hyperglycemia, hypertension, dyslipidemia, and inflammation have been proposed to account for the development of nephropathy in diabetic subjects. The beneficial effects of enalapril on diabetic nephropathy are known. However, the effects of trimetazidine (TMZ) are still unknown. We aimed a
PMID 25010195

Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney.

Xu J1, Nie X1, Cai X2, Cai CL2, Xu PX3.
Developmental biology.Dev Biol.2014 Jul 1;391(1):17-31. doi: 10.1016/j.ydbio.2014.04.006. Epub 2014 Apr 12.
Tbx18 has been shown to be essential for ureteral development. However, it remains unclear whether it plays a direct role in kidney development. Here we addressed this by focusing on examining the pattern and contribution of Tbx18+ cells in the kidney and its role in kidney vascular development. Exp
PMID 24727670

Spontaneous glomerular mesangial lesions in common marmoset monkeys (Callithrix jacchus): a benign non-progressive glomerulopathy.

Collins MG1, Rogers NM, Jesudason S, Kireta S, Brealey J, Toby Coates P.
Journal of medical primatology.J Med Primatol.2014 Jun 30. doi: 10.1111/jmp.12134. [Epub ahead of print]
BACKGROUND: Common marmosets are known to develop an IgM glomerulopathy, which has been linked with 'wasting marmoset' syndrome. This study investigated renal pathology in a colony of marmosets, with and without weight loss.METHODS: Renal histology, immunofluorescence, and electron microscopy were p
PMID 24980800

Japanese Journal

片側低形成腎に重症IgA腎症を合併した1症例

布山正貴,池田裕一,渡邊常樹,磯山恵一
Nihon Shoni Jinzobyo Gakkai Zasshi 26(1), 88-93, 2013
　症例は11歳男児。生後から右腎低形成を指摘されていたが，11歳時，感冒を契機に肉眼的血尿が出現した後，蛋白尿，血尿が3か月間持続した。膀胱鏡で左右尿管から採尿し同程度の血尿，蛋白尿を認めたため両腎に同様の腎疾患が存在すると推定した。左健側腎を開放腎生検しIgA腎症重症例と診断した。ステロイドパルス療法後，多剤併用療法を行い3か月後に蛋白尿は消失した。残存ネフロン数が減少した先天性腎疾患に後天性腎 …
NAID 130003384549

Membranous Glomerulonephropathy in a Hatano Low-avoidance Rat

Yasuno Kyohei,Sakashita Haruka,Kobayashi Ryosuke [他],ARAKI Saori,SAITO Rio,SHIROTA Mariko,KAMIIE Junichi,SHITORA Kinji
Journal of Toxicologic Pathology 26(2), 203-208, 2013
… Histological tests revealed frequent presence of irregularly sized eosinophilic hyaline materials on the capillary wall and in the mesangium of renal glomeruli. …
NAID 130003362375

Distinct Distribution of the Tensin Family in the Mouse Kidney and Small Intestine

NISHINO Tomohiro,SASAKI Nobuya,CHIHARA Masataka [他],NAGASAKI Ken-ichi,TORIGOE Daisuke,KON Yasuhiro,AGUI Takashi
Experimental animals 61(5), 525-532, 2012-10-01
… Immunohistochemical staining revealed that Tns1 was predominantly localized to the mesangium of glomeruli and renal tubules. …
NAID 10031121857