WordNet

bring disorder to (同)disarray
a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time" (同)upset
a disturbance of the peace or of public order
dangerous to health; characterized by progressive and uncontrolled growth (especially of a tumor)
not arranged in order (同)unordered

PrepTutorEJDIC

〈U〉『無秩序』,混乱,乱雑(confusion) / 《しばしば複数形で》(社会的・政治的な)粉争,騒動 / 〈C〉(肉体的・精神的な)不調,異常,障害 / …‘の'秩序を乱す / 〈心身〉‘に'異常を起こさせる
悪意のある,敵意のある / (病気が)悪性の

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Extranodal soft tissue Rosai-Dorfman disease of the head and neck and its diagnostic difficulty.

Yajima M1, Nakajima K1, Hirato J2, Chikamatsu K3.
Auris, nasus, larynx.Auris Nasus Larynx.2015 Oct 29. pii: S0385-8146(15)00216-3. doi: 10.1016/j.anl.2015.09.008. [Epub ahead of print]
Rosai-Dorfman disease (RDD) is a rare proliferative histiocytic disorder that is characterized by persistent massive lymphadenopathy mimicking malignant tumors. Extranodal RDD is uncommon, and more severe fibrosis and fewer histiocytes in lesions make the diagnosis of RDD more difficult than that of
PMID 26526642

Secondary histiocytic sarcoma may cause apparent persistence or recurrence of minimal residual disease in childhood acute lymphoblastic leukemia.

Alten J1, Klapper W2, Leuschner I3, Eckert C4, Beier R5, Vallo E6, Krause M1, Claviez A1, Vieth S1, Bleckmann K1, Möricke A1, Schrappe M1, Cario G1.
Pediatric blood & cancer.Pediatr Blood Cancer.2015 Sep;62(9):1656-60. doi: 10.1002/pbc.25523. Epub 2015 Apr 1.
Histiocytic sarcoma (HS) is a rare disease with poor prognosis which may develop subsequent to acute lymphoblastic leukemia (ALL). Here we report two children treated within the AIEOP-BFM ALL 2009 trial: one patient succumbed to fulminant hemophagocytic lymphohistiocytosis triggered by HS during ALL
PMID 25833113

Deficiency of β Common Receptor Moderately Attenuates the Progression of Myeloproliferative Neoplasm in NrasG12D/+ Mice.

Zhang J1, Ranheim EA2, Du J1, Liu Y1, Wang J1, Kong G1, Zhang J3.
The Journal of biological chemistry.J Biol Chem.2015 Jul 31;290(31):19093-103. doi: 10.1074/jbc.M115.653154. Epub 2015 Jun 16.
Activating Ras signaling is a major driver in juvenile and the myeloproliferative variant of chronic myelomonocytic leukemia (JMML/MP-CMML). Numerous studies suggest that GM-CSF signaling plays a central role in establishing and maintaining JMML/MP-CMML phenotypes in human and mouse. However, it rem
PMID 26082490