WordNet

(botany) either of the two parts of a bilabiate corolla or calyx
either the outer margin or the inner margin of the aperture of a gastropods shell
either of two fleshy folds of tissue that surround the mouth and play a role in speaking
an oily organic compound insoluble in water but soluble in organic solvents; essential structural component of living cells (along with proteins and carbohydrates) (同)lipide, lipoid
an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
the basic unit of money in Papua New Guinea

PrepTutorEJDIC

〈C〉『くちびる』,口もと / 《複数形で》(発音器官としての)くちびる,口 / 〈U〉《俗》生意気な言葉 / 〈C〉(容器などの)口,へり,縁;(峡谷・火山などの)口 / 〈C〉(植物の)唇弁(しんべん)
脂質,あぶら

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1. 筋肉におけるエネルギー代謝 energy metabolism in muscle
2. 血小板生物学 platelet biology
3. T細胞受容体シグナル伝達 t cell receptor signaling
4. 新生児胆汁うっ滞の原因 causes of neonatal cholestasis
5. 腎細胞癌の疫学、病理、および病因 epidemiology pathology and pathogenesis of renal cell carcinoma

Phosphatidylinositol (3,4) bisphosphate-specific phosphatases and effector proteins: A distinct branch of PI3K signaling.

Li H1, Marshall AJ2.
Cellular signalling.Cell Signal.2015 Sep;27(9):1789-98. doi: 10.1016/j.cellsig.2015.05.013. Epub 2015 May 27.
The ubiquitously expressed phosphoinositide 3-kinase (PI3K) family of lipid kinases control diverse cellular functions including cell survival, proliferation, metabolism and migration. Class I PI3Ks generate two distinct 3-phosphoinositide lipid messengers, PI(3,4,5)P3 (PIP3) and PI(3,4)P2, that rec
PMID 26022180

Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation.

Fazolini NP1, Cruz AL, Werneck MB, Viola JP, Maya-Monteiro CM, Bozza PT.
Cell cycle (Georgetown, Tex.).Cell Cycle.2015 Aug 18;14(16):2667-76. doi: 10.1080/15384101.2015.1041684. Epub 2015 May 27.
Accumulating evidence suggests that obesity and enhanced inflammatory reactions are predisposing conditions for developing colon cancer. Obesity is associated with high levels of circulating leptin. Leptin is an adipocytokine that is secreted by adipose tissue and modulates immune response and infla
PMID 26017929

Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway.

Tao W1, Wu J1, Xie BX1, Zhao YY1, Shen N1, Jiang S1, Wang XX1, Xu N1, Jiang C1, Chen S1, Gao X1, Xue B2, Li CJ3.
The Journal of biological chemistry.J Biol Chem.2015 Aug 14;290(33):20086-97. doi: 10.1074/jbc.M115.657742. Epub 2015 Jun 25.
Elevated circulating free fatty acid levels are important contributors to insulin resistance in the muscle and liver, but the underlying mechanisms require further elucidation. Here, we show that geranylgeranyl diphosphate synthase 1 (GGPPS), which is a branch point enzyme in the mevalonic acid path
PMID 26112408

(−)-Epigallocatechin gallate suppresses adipocyte differentiation through the MEK/ERK and PI3K/Akt pathways

Kim Hyojung,Sakamoto Kazuichi,坂本和一
Cell biology international 36(2), 147-153, 2012-02-00
… Oil Red O staining showed significantly reduced intracellular lipid accumulation, especially with EGCG. … EGCG also caused a significant decrease in the transcription of FoxO1 – the forkhead transcription factor class O1 involved in adipocyte differentiation – via the PI3K (phosphoinositide 3-kinase)/Akt and MEK [MAPK (mitogen-activated protein kinase)/ERK (extracellular-signal-regulated kinase) kinase] pathways. …
NAID 120005247071

Cirsium japonicum Flavones Enhance Adipocyte Differentiation and Glucose Uptake in 3T3-L1 Cells

Liao Zhiyong,Wu Zhihua,Wu Mingjiang
Biological and Pharmaceutical Bulletin 35(6), 855-860, 2012
… The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in glucose and lipid homeostasis. … The flavones-induced effects in 3T3-L1 cells were abolished by the PPARγ antagonist, GW9662, and by the phosphatidylinositol 3-kinase (PI3K) inhibitor, wortmannin. …
NAID 130001872165