WordNet

of or relating to or consisting of muscle; "muscular contraction"
having or suggesting great physical power or force; "the muscular and passionate Fifth Symphony"
a thin plate or layer (especially of bone or mineral)

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『助肉の』,筋肉でできた / 筋肉による / 筋肉の発達した
薄層,薄片,薄板

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/14 12:18:21」(JST)

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The lamina muscularis mucosae (or muscularis mucosae) is the thin layer of smooth muscle found in most parts^[where?] of the gastrointestinal tract, located outside the lamina propria mucosae and separating it from the submucosa.

In the gastrointestinal tract, the term mucosa or "mucous membrane" refers to the combination of epithelium, lamina propria, and (where it occurs) muscularis mucosae.^[1] The etymology suggests this, since the Latin names translate to "the mucosa's own special layer" (lamina propria mucosae) and "muscular layer of the mucosa" (lamina muscularis mucosae).

The muscularis mucosae is composed of several thin layers of smooth muscle fibers oriented in different ways which keep the mucosal surface and underlying glands in a constant state of gentle agitation to expel contents of glandular crypts and enhance contact between epithelium and the contents of the lumen.

References[edit source | edit]

^ H.G. Burkitt et al., Wheater's Functional Histology, 3rd ed.

Additional images[edit source | edit]

Section of the human esophagus. Moderately magnified.
Section of mucous membrane of human stomach, near the cardiac orifice.
Section of mucous membrane of human rectum. X 60.
Layers of stomach wall
General structure of the gut wall showing the Muscularis mucosa.

External links[edit source | edit]

Bioweb at UWLAX aplab
Muscularis+mucosae at eMedicine Dictionary
Histology at OU 14_08 - "Lung"
Physiology at MCG 6/6ch1/s6ch1_11
Organology at UC Davis digestive/mammal/system1/system4 - "Mammal, whole system (LM, Low)"
UIUC Histology Subject 830

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UpToDate Contents

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English Journal

Binding of fluorescently labeled cholera toxin subunit B to glycolipids in the human submandibular gland and inhibition of binding by periodate oxidation and by galactose.

Kirkeby S1.
Biotechnic & histochemistry : official publication of the Biological Stain Commission.Biotech Histochem.2016 Jan;91(1):1-8. doi: 10.3109/10520295.2015.1065000. Epub 2015 Oct 15.
FITC-labeled cholera toxin subunit B (CTB) stained the surfaces of cells of mucous acini in the submandibular gland. CTB, also called choleragenoid, binds to the GM1 glycolipid in the cell membrane. The binding in most acini was inhibited by periodic acid oxidation of the sections, while some acini
PMID 26472148

Formation of Segmental Rounded Nodules During Infiltration of Adult T-Cell Leukemia Cells Into the Ocular Mucous Membrane.

Kamoi K1, Nagata Y, Mochizuki M, Kobayashi D, Ohno N, Uchimaru K, Tojo A, Ohno-Matsui K.
Cornea.Cornea.2016 Jan;35(1):137-9. doi: 10.1097/ICO.0000000000000689.
PURPOSE: To document a case of adult T-cell leukemia (ATL) cell infiltration into the ocular mucous membrane that presented with rounded nodule formation.METHODS: Observational case report.RESULTS: A 36-year-old woman presented with bilateral conjunctival hyperemia and small papules on the legs and
PMID 26555589

Treatment Modalities and Clinical Outcomes in Ocular Sequelae of Stevens-Johnson Syndrome Over 25 Years-A Paradigm Shift.

Iyer G1, Srinivasan B, Agarwal S, Pillai VS, Ahuja A.
Cornea.Cornea.2016 Jan;35(1):46-50. doi: 10.1097/ICO.0000000000000680.
PURPOSE: To highlight and compare the outcomes of management for the ocular sequelae of Stevens-Johnson syndrome (SJS) over 25 years in a tertiary eye care institute.METHODS: A retrospective chart review of 798 eyes of 399 patients with SJS evaluated between January 1990 and December 2004 (group I)
PMID 26555585

Japanese Journal

大腸憩室疾患に伴う粘膜脱症候群様病変の2例

坂田玄太郎,野崎良一,實藤隼人,大湾朝尚,入江朋子,佐藤太一,深見賢作,山根圭太郎,中村寧,田中正文,高野正太,福永光子,佐伯泰愼,久野三朗,緒方俊二,山田一隆,高野正博
日本大腸肛門病学会雑誌 65(4), 209-213, 2012-04-01
大腸憩室疾患に伴う稀な粘膜脱症候群様病変2症例を経験した．大腸憩室疾患で長期経過観察中に憩室多発部位にみられた病変である．内視鏡所見は，境界不明瞭な発赤調の多発した粘膜下腫瘍様形態であった．病理学的には粘膜筋板から粘膜固有層上方へ伸びる平滑筋線維の増生，いわゆる線維筋症を認め，直腸にみられる粘膜脱症候群に類似した所見であった．経過中，腺腫や早期癌の併存がみられ，内視鏡摘除を施行した．本病変の確定診 …
NAID 10030360070

粘膜筋板の断裂と粘膜内への進展を呈した小腸海綿状リンパ管腫の1例

堀江秀樹,加藤隆弘,小島孝雄,橋本宏明,福田信宏,高野幸彦,大洞昭博,奥田順一,井田和徳,下川邦泰
日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy 53(7), 1804-1808, 2011-07-20
腹痛と嘔吐を主訴とする20歳代女性，腹部CTで小腸腫瘍が疑われ，ダブルバルーン小腸内視鏡検査で，上部空腸に約30mm大の黄白色の腫瘍を認めた．小腸リンパ管腫を疑い，空腸部分切除術を施行した．切除標本では，腫瘤部の粘膜筋板が薄層化し，一部に破綻を認めた．リンパ濾胞の粘膜内への進展がみられ，海綿状リンパ管腫と診断した．本症例が有症状を呈する大きさに至った一因として粘膜筋板の破綻の関与が示唆された．
NAID 10029562491

Cytoarchitecture of the lamina muscularis mucosae and distribution of the lymphatic vessels in the human stomach

AKASHI Yuichi,NOGUCHI Tsuyoshi,NAGAI Kaoruko,KAWAHARA Katsunobu,SHIMADA Tatsuo
Medical molecular morphology : official journal of the Japanese Society for Clinical Molecular Morphology 44(1), 39-45, 2011-03-01
NAID 10029036569

「粘膜筋板」

Muscularis mucosae
	Section of duodenum of cat. X 60. (Muscularis mucosae labeled at right, third from the top.)
Latin	Lamina muscularis mucosae
Gray's	subject #245 1144