イソニアジドメタンスルホン酸ナトリウム
WordNet
- a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
- antibacterial drug (trade name Nydrazid) used to treat tuberculosis (同)INH, Nydrazid
PrepTutorEJDIC
- ソジウム,ナトリウム(金属元素;化学記号はNa)
UpToDate Contents
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English Journal
- [A case of isoniazid sodium methanesulfonate induced interstitial pneumonia].
- Matsushima H1, Sugita Y, Yanagisawa T, Ubukata M, Kurosawa T, Yoshida F, Kanazawa M.
- Kekkaku : [Tuberculosis].Kekkaku.2003 May;78(5):401-6.
- A 71-year-old male was admitted to our hospital with dyspnea on effort. He had been prescribed rifampicin, isoniazid sodium methanesulfonate (IHMS), and ethambutol for pulmonary tuberculosis, and ursodesoxycholic acid for alcoholic liver dysfunction. The chest HRCT revealed diffuse ground-glass atte
- PMID 12806983
- Hydrophobic ion pairing of isoniazid using a prodrug approach.
- Zhou H1, Lengsfeld C, Claffey DJ, Ruth JA, Hybertson B, Randolph TW, Ng KY, Manning MC.
- Journal of pharmaceutical sciences.J Pharm Sci.2002 Jun;91(6):1502-11.
- Inhalation therapy for infectious lung diseases, such as tuberculosis, is currently being explored, with microspheres being used to target alveolar macrophages. One method of drug encapsulation into polymeric microspheres to form hydrophobic ion-paired (HIP) complexes, and then coprecipitate the com
- PMID 12115849
- [A case of tuberculous pleurisy associated with myoclonus and Quincke's edema due to isoniazid and isoniazid sodium methanesulfonate].
- Yagi S, Moriya O, Nakajima M, Umeki S, Hino J, Soejima R.
- Kekkaku : [Tuberculosis].Kekkaku.1989 Jun;64(6):407-12.
- A case of tuberculous pleurisy associated with myoclonus and Quincke's edema due to isoniazid (INH) and isoniazid sodium methanesulfonate (IHMS) was reported. A 75-year-old man was admitted to our division because of chest discomfort and the left chest pain of one month's duration. A conventional ch
- PMID 2796112
Japanese Journal
- Isoniazid sodium methanesulfonateによる薬剤性肺炎の1例
- 松島 秀和,杉田 裕,柳沢 勉,生方 幹夫,黒沢 知徳,吉田 文香,金沢 実
- 結核 78(5), 401-406, 2003-05-15
- … He had been prescribed rifampicin, isoniazid sodium methanesulfonate (IHMS), and ethambutol for pulmonary tuberculosis, and ursodesoxycholic acid for alcoholic liver dysfunction. … In the past, 5 cases of isoniazid induced interstitial pneumonia were reported, but IHMS induced interstitial pneumonia has not been reported. …
- NAID 130001428706
- イソニアジドメタンスルホン酸ナトリウム・リン酸ピリドキサールカルシウム散の着色変化に及ぼす混合様式の影響
- 寺岡 麗子,大塚 誠,松田 芳久,杉本 功
- 病院薬学 22(2), 198-205, 1996-04-10
- … The effect of grinding on the coloration of the isoniazid sodium methanesulfonate (IHMS) and pyridoxal calcium phosphate (PAL-P-Ca) compound was investigated using three types of mixers, namely a twin -shell mixer, a ball mill, or a chaser mill. …
- NAID 110001799569
- A case of tuberculous pleurisy associated with myoclonus and Quincke's edema due to isoniazid and isoniazid sodium methanesulfonate.
- 矢木 晋,守屋 修,中島 正光,梅木 茂宣,日野 二郎,副島 林造
- 結核 64(6), 407-412, 1989
- … A case of tuberculous pleurisy associated with myoclonus and Quincke's edema due to isoniazid (INH) and isoniazid sodium methanesulfonate (IHMS) was reported.<BR>A75-ear-old man was admitted to our division because of chest discomfort and the left chest pain of one month's duration. …
- NAID 130001410779
Related Links
- 25 イソニアジドメタンスルホン酸ナトリウム散 Isoniazid Soduim Methanesulfonate Powder 溶出試験 本品の表示量に従いイソニアジドメタンスルホン酸ナトリウム (C7H8N3NaO4S・H2O)約0.1gに対応する量を精密に量り,試験液に水900mLを ...
- [商品名]ネオイスコチン [レコード番号]6222005A1027 [添付文書日付]9906 [作改種別]カイテイ [薬効分類]6222 [規制区分] 指 要指 [一般名]イソニアジドメタンスルホン酸ナトリウム [薬品名] ネオイスコチン NEOISCOTIN ...
- イソニアジドメタンスルホン酸ナトリウム水和物 Isoniazid Sodium Methanesulfonate Hydrate(Sodium Methaniazide) 略名 IHMS 化学名 sodium(2-isonicotinoylhydrazino)methanesulfonate hydrate 分子式 C 7 H 8 N 3 NaO 4 S・H 2 O ...
★リンクテーブル★
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- 英
- isoniazid sodium methanesulfonate
- 同
- [[]]
- 関
- イソニアジド、抗結核薬、結核、ビタミンB6、ビタミンB6欠乏症
概念
作用
- ヒト型結核菌H37Rv株に対する最小発育阻止濃度(MIC)は、0.1μg/ml(10%血清加Kirchner培地で測定)で、INHと同等の抗菌力を示す。
- マウス実験的結核症(H37Rv株)に対して、同量投与の場合、本剤はINHとほぼ同等の治療効果を示す
重大な副作用
- 2. 痙攣 頻度不明注1)
- 3. 視神経炎、視神経萎縮
- 頻度不明注1)
- 症状:視力低下、中心暗点等
- 処置方法:ビタミンB6投与等
- 4. 末梢神経炎
- 頻度不明注1)
- 症状:四肢の異常感覚、しびれ感、知覚障害、腱反射低下、筋力低下、筋萎縮等
- 処置方法:ビタミンB6投与等
禁忌
- 重篤な肝障害のある患者[肝障害が悪化するおそれがある。]
添付文書
- http://www.info.pmda.go.jp/go/pack/6222005A1035_1_01/6222005A1035_1_01?view=body
[★]
- 関
- mesilate、mesylate、methanesulfonic acid
[★]
イソニアジド INH