WordNet

a salt or ester of maleic acid; used as a nontricyclic antidepressant drug for psychomotor activation

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1. 中毒性結膜炎 toxic conjunctivitis
2. 妊娠中絶の概要 overview of pregnancy termination
3. アレルギー性結膜炎：マネージメント allergic conjunctivitis management
4. 急性持続性視力喪失が認められた成人に対するアプローチ approach to the adult with acute persistent visual loss
5. 閉塞隅角緑内障 angle closure glaucoma

Irsogladine maleate regulates epithelial barrier function in tumor necrosis factor-α-stimulated human gingival epithelial cells.

Fujita T, Yumoto H, Shiba H, Ouhara K, Miyagawa T, Nagahara T, Matsuda S, Kawaguchi H, Matsuo T, Murakami S, Kurihara H.SourceDepartment of Periodontal Medicine, Division of Frontier Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. tfuji@hiroshima-u.ac.jp
Journal of periodontal research.J Periodontal Res.2012 Feb;47(1):55-61. doi: 10.1111/j.1600-0765.2011.01404.x. Epub 2011 Sep 6.
BACKGROUND AND OBJECTIVE: As epithelial cells function as a mechanical barrier, the permeability of the gingival epithelial cell layer indicates a defensive capability against invasion by periodontal pathogens. We have reported the expression of claudin-1 and E-cadherin, key regulators of permeabili
PMID 21895660

Comparison of the efficacy of irsogladine maleate and famotidine for the healing of gastric ulcers after Helicobacter pylori eradication therapy: a randomized, controlled, prospective study.

Murakami K, Okimoto T, Kodama M, Tanahashi J, Mizukami K, Shuto M, Abe H, Arita T, Fujioka T.SourceDepartment of Gastroenterology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, Japan. murakam@med.oita-u.ac.jp
Scandinavian journal of gastroenterology.Scand J Gastroenterol.2011 Mar;46(3):287-92. Epub 2010 Nov 14.
OBJECTIVE: Helicobacter pylori eradication therapy alone cannot heal gastric ulcers in Japanese patients. Irsogladine has previously been shown to accelerate the healing of gastric ulcers after H. pylori eradication therapy. And we previously reported that histamine H(2) receptor antagonists inhibit
PMID 21073372

西村達朗,橋本真一,河郷亮 [他],白澤友宏,横田恭之,柴田大明,岡本健志,西川潤,坂井田功
山口医学 = Yamaguchi medical journal 64(1), 41-45, 2015-02
… Administration of irsogladine maleate 4 mg/day and rebamipide 300 mg/day was begun, and then by changing to a low-residue diet to match the cyclic phase of the thrombocytopenia of about once per month, no progression of the anemia was seen for about 1 year. …
NAID 120005601215