WordNet

a line of small holes for tearing at a particular place
the act of punching a hole (especially a row of holes as for ease of separation)
a hole made in something; "a perforation of the eardrum"
of or relating to or inside the intestines; "intestinal disease" (同)enteric, enteral

PrepTutorEJDIC

〈U〉穴をあけること / 〈C〉《しばしば複数形で》穴,ミシン目,切り取り線
腸[内]の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/30 14:10:35」(JST)

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Gastrointestinal perforation is a complete penetration of the wall of the stomach, small intestine or large bowel, resulting in intestinal contents flowing into the abdominal cavity. Perforation of the intestines results in the potential for bacterial contamination of the abdominal cavity (a condition known as peritonitis). Perforation of the stomach can lead to a chemical peritonitis due to leaked gastric acid. Perforation anywhere along the gastrointestinal tract is a surgical emergency.

Signs and symptoms

Sudden attack of pain in epigastrium to the right of midline in case of perforation of duodenal ulcer. In case of gastric ulcer the pain is in epigastrium. There is history of burning pain in epigastrium, flatulence and dyspepsia. History of drug intake without sufficient food intake may be present. In case of intestinal perforation pain starts from the site of perforation, visceral, and then spreads all over the abdomen. In any case there is board like rigidity of abdomen, tenderness, and rebound tenderness. After some time the abdomen becomes silent, heart sounds can be heard all over. Patient stops passing flatus and motion, abdomen is distended. Gastrointestinal perforation results in severe abdominal pain intensified by movement, nausea and vomiting. Later symptoms include fever and or chills.

Causes

Underlying causes include gastric ulcer, appendicitis, gastrointestinal cancer, diverticulitis, superior mesenteric artery syndrome, trauma and ascariasis. Typhoid fever, non-steroidal anti-inflammatory drugs, ingestion of corrosives may also be responsible.^{[citation needed]}

Diagnosis

On x-rays, free gas/air may be visible in the abdominal cavity. The perforation can often be visualised using computed tomography. White blood cells are often elevated. Visible signs can occasionally include a ridged abdomen on palpation.

Treatment

Treatment depends on the underlying cause. Surgical intervention is nearly always required in form of exploratory laparotomy and closure of perforation with peritoneal wash. Conservative treatment is indicated in case patient is nontoxic and clinically stable, these patients are to be treated with intravenous fluids, antibiotics, nasogastric aspiration and bowel rest. Consultation with a specialist is often needed.

References

External Links

Gastrointestinal perforation - MedlinePlus

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UpToDate Contents

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1. Overview of gastrointestinal tract perforation
2. 新生児の自然発生的な腸管穿孔 spontaneous intestinal perforation of the newborn
3. 成人患者における外傷性胃腸障害 traumatic gastrointestinal injury in the adult patient
4. 婦人科外科手術の合併症 complications of gynecologic surgery
5. 急性合併性憩室炎のマネージメント management of acute complicated diverticulitis

English Journal

Development of a novel approach to safely couple the intestine to a distraction-induced device for intestinal growth: use of reconstructive tissue matrix.

Ralls MW, Sueyoshi R, Herman R, Utter B, Czarnocki I, Luntz J, Brei D, Teitelbaum DH.SourceSection of Pediatric Surgery, Department of Surgery and the C.S, Mott Children's Hospital, University of Michigan, 1540 E. Hospital Dr., SPC 4211, Ann Arbor, 48109-4211, MI, USA.
Pediatric surgery international.Pediatr Surg Int.2013 Feb;29(2):151-6. doi: 10.1007/s00383-012-3198-z.
BACKGROUND: Distraction-induced intestinal growth may be a novel treatment for short bowel syndrome. Longitudinal, distractive tension created by the application of force creates a significant challenge: to produce adequate force, yet not cause perforation at the fixation points. This paper describe
PMID 23108982

Multiple NSAID-Induced Hits Injure the Small Intestine: Underlying Mechanisms and Novel Strategies.

Boelsterli UA, Redinbo MR, Saitta KS.Source* Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut.
Toxicological sciences : an official journal of the Society of Toxicology.Toxicol Sci.2013 Feb;131(2):654-67. doi: 10.1093/toxsci/kfs310. Epub 2012 Oct 22.
Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause serious gastrointestinal (GI) injury including jejunal/ileal mucosal ulceration, bleeding, and even perforation in susceptible patients. The underlying mechanisms are largely unknown, but they are distinct from those related to gastric injury.
PMID 23091168

Japanese Journal

上部消化管造影検査後のバリウム糞石により大腸穿孔を起こした1例

日本大腸肛門病学会雑誌 69(7), 374-378, 2016
NAID 130005158828

短期間に3度小腸穿孔をきたしたコレステロール塞栓症の1例

日本消化器病学会雑誌 113(5), 804-812, 2016
NAID 130005150377

腸重積および穿孔性腹膜炎を合併した回腸炎症性線維性ポリープの1例

日本腹部救急医学会雑誌 36(1), 177-181, 2016
NAID 130005149425

「腸穿孔」

Gastrointestinal perforation
	Classification and external resources
	; Free air under the right hemidiaphragm from a bowel perforated.
ICD-10	K63.1, S36.9
ICD-9	569.83, 863.9
DiseasesDB	34042
MedlinePlus	000235
eMedicine	med/2822

　　[★]

英: intestinal perforation、bowel perforation
関: 腸管穿孔

「腸管穿孔」

　　[★]

英: intestinal perforation
関: 腸穿孔

「bowel perforation」

　　[★]

腸穿孔

関: intestinal perforation

「intestinal」

　　[★]

adj.

腸の、腸管の、腸管内の、消化器系の

関: alimentary system、bowel、digestive system、enteric、enteric canal、entero、gastrointestinal、gastrointestinal system、GI、gut、intestinal tract、intestine

「perforation」

　　[★]

n.

穿孔

関: bore、drill、perforate

リンク元	「腸穿孔」「腸管穿孔」「bowel perforation」
関連記事	「intestinal」「perforation」

匿名

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案内

案内

intestinal perforation