inositol-1,4,5-triphosphate receptors

イノシトール1,4,5-トリスリン酸受容体

WordNet

1. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
2. an optically inactive alcohol that is a component of the vitamin B complex

PrepTutorEJDIC

1. =sense organ / 受信装置

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• 1. 肥満細胞：表面受容体とシグナル伝達 mast cells surface receptors and signal transduction
• 2. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction
• 3. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
• 4. 血小板生物学 platelet biology
• 5. T細胞受容体シグナル伝達 t cell receptor signaling

English Journal

• Myosin Va and Endoplasmic Reticulum Calcium Channel Complex Regulates Membrane Export during Axon Guidance.

• Wada F1, Nakata A1, Tatsu Y2, Ooashi N1, Fukuda T1, Nabetani T1, Kamiguchi H3.
• Cell reports.Cell Rep.2016 May 10;15(6):1329-44. doi: 10.1016/j.celrep.2016.04.021. Epub 2016 Apr 28.
• During axon guidance, growth cones navigate toward attractive cues by inserting new membrane on the cue side. This process depends on Ca(2+) release from endoplasmic reticulum (ER) Ca(2+) channels, but the Ca(2+) sensor and effector governing this asymmetric vesicle export remain unknown. We identif
• PMID 27134178

• The non-apoptotic action of Bcl-xL: regulating Ca2+ signaling and bioenergetics at the ER-mitochondrion interface.

• Williams A1,2,3, Hayashi T1,4, Wolozny D2, Yin B2, Su TC1, Betenbaugh MJ5, Su TP6.
• Journal of bioenergetics and biomembranes.J Bioenerg Biomembr.2016 May 7. [Epub ahead of print]
• Bcl-2 family proteins are known to competitively regulate Ca2+; however, the specific inter-organelle signaling pathways and related cellular functions are not fully elucidated. In this study, a portion of Bcl-xL was detected at the ER-mitochondrion interface or MAM (mitochondria-associated ER membr
• PMID 27155879

• Recessive and Dominant De Novo ITPR1 Mutations Cause Gillespie Syndrome.

• Gerber S1, Alzayady KJ2, Burglen L3, Brémond-Gignac D4, Marchesin V5, Roche O4, Rio M6, Funalot B7, Calmon R8, Durr A9, Gil-da-Silva-Lopes VL10, Ribeiro Bittar MF10, Orssaud C4, Héron B11, Ayoub E2, Berquin P12, Bahi-Buisson N13, Bole C14, Masson C15, Munnich A6, Simons M5, Delous M16, Dollfus H17, Boddaert N8, Lyonnet S18, Kaplan J1, Calvas P19, Yule DI2, Rozet JM20, Fares Taie L1.
• American journal of human genetics.Am J Hum Genet.2016 May 5;98(5):971-80. doi: 10.1016/j.ajhg.2016.03.004. Epub 2016 Apr 21.
• Gillespie syndrome (GS) is a rare variant form of aniridia characterized by non-progressive cerebellar ataxia, intellectual disability, and iris hypoplasia. Unlike the more common dominant and sporadic forms of aniridia, there has been no significant association with PAX6 mutations in individuals wi
• PMID 27108797

Japanese Journal

• Interleukin-13 enhanced Ca[2+] oscillations in airway smooth muscle cells.

• Matsumoto Hisako,Hirata Yutaka,Otsuka Kojiro,Iwata Toshiyuki,Inazumi Aya,Niimi Akio,Ito Isao,Ogawa Emiko,Muro Shigeo,Sakai Hiroaki,Chin Kazuo,Oku Yoshitaka,Mishima Michiaki
• Cytokine 57(1), 19-24, 2012-01-00
• … The aim of this study was to assess effects of IL-13 on Ca[2+] oscillations in response to leukotriene D4 (LTD4) in human cultured ASMCs. … LTD4-induced Ca[2+] oscillations in ASMCs pretreated with IL-13 were imaged by confocal microscopy. …
• NAID 120003726117

• 細胞質内 Ca^<2+> 振動における細胞内 Ca^<2+> ストアの役割

• 北嶋 龍雄,澤井 有紀,西山 誠
• 電子情報通信学会技術研究報告. NC, ニューロコンピューティング 104(759), 7-12, 2005-03-22
• 神経細胞内のCa^<2+>振動・伝搬現象は神経細胞で行われているさまざまな情報処理機能や軸索における成長円錐運動の基礎過程として重要な役割を果たしていると考えられている。特に、細胞内のCa^<2+>ストアである小胞体膜上に存在するIP3受容体、RyR受容体活性によるCa^<2+>放出、Ca^<2+>ポンプによるCa^<2+>取り込みがこれ …
• NAID 110003234156

• Modulation of dexamethasone-induced thymocyte apoptosis by heat-shock protein 90-binding agents

• Ohta K,Okoshi R,Wakabayashi M,Sato Y,Kizaki H
• Bulletin of Tokyo Dental College 45(1), 1-8, 2004-02-00
• … The expression of inositol 1, 4, 5-triphosphate receptors, which were shown to be involved in dexamethasone-induced apoptosis, did not participate in the inhibition of apoptosis. …
• NAID 110004690131

Related Links

• Inositol 1,4,5-triphosphate receptors and NAD(P)H mediate ...

1. Neuroscience. 2009 Apr 21;160(1):51-60. doi: 10.1016/j.neuroscience.2009.02.013. Epub 2009 Feb 13. Inositol 1,4,5-triphosphate receptors and NAD(P)H mediate Ca2+ signaling required for hypoxic preconditioning of hippocampal ...

• INOSITOL 1,4,5-TRIPHOSPHATE RECEPTORS AND NAD(P)H

INOSITOL 1,4,5-TRIPHOSPHATE RECEPTORS AND NAD(P)H MEDIATE Ca2 SIGNALING REQUIRED FOR HYPOXIC PRECONDITIONING OF HIPPOCAMPAL NEURONS P. E. BICKLER,* C. S. FAHLMAN, J. GRAY AND W. MCKLEROY

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★リンクテーブル★

リンク元	「イノシトール1,4,5-トリスリン酸受容体」
関連記事	「triphosphate」「inositol」

「イノシトール1,4,5-トリスリン酸受容体」

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英

inositol-1,4,5-triphosphate receptors, inositol 1,4,5-trisphosphate receptor,IP3 receptor, IP3R

関

イノシトール三リン酸受容体、IP3受容体

「triphosphate」

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三リン酸エステル、三リン酸塩、三リン酸

関

trisphosphate

「inositol」

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イノシトール

関

myoinositol