WordNet
- not yet mature
- characteristic of a lack of maturity; "immature behavior"
- the chief phagocytic leukocyte; stains with either basic or acid dyes (同)neutrophile
PrepTutorEJDIC
- (人・動物・果実などが)未[成]熟な,円熟(成熟)していない / おとなげない
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/27 20:41:03」(JST)
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- 1. 末梢血塗抹標本の評価 evaluation of the peripheral blood smear
- 2. 好中球増多症の患者へのアプローチ approach to the patient with neutrophilia
- 3. 好中球機能異常症の検査での評価 laboratory evaluation of neutrophil disorders
- 4. 原因不明の好中球減少症を有する成人に対するアプローチ approach to the adult with unexplained neutropenia
- 5. 好中球増多症の原因 causes of neutrophilia
English Journal
- Inhibitors of CXC chemokine receptor type 4: putative therapeutic approaches in inflammatory diseases.
- Hummel S, Van Aken H, Zarbock A.Author information aDepartment of Anesthesiology, Intensive Care and Pain Medicine, University of Muenster bMax-Plank Institute Muenster, Muenster, Germany.AbstractPURPOSE OF REVIEW: The CXC chemokine receptor type 4 (CXCR4), which is a G-protein coupled receptor, and its ligand CXCL12 play an important role in neutrophil homeostasis and inflammation. This review focuses on involvement of the CXCL12/CXCR4 axis in inflammation and different inflammatory diseases and depicts that blocking CXCR4 is an attractive therapeutic strategy.
- Current opinion in hematology.Curr Opin Hematol.2014 Jan;21(1):29-36. doi: 10.1097/MOH.0000000000000002.
- PURPOSE OF REVIEW: The CXC chemokine receptor type 4 (CXCR4), which is a G-protein coupled receptor, and its ligand CXCL12 play an important role in neutrophil homeostasis and inflammation. This review focuses on involvement of the CXCL12/CXCR4 axis in inflammation and different inflammatory disease
- PMID 24275689
- Lipopolysaccharide-Binding Protein as Marker of Fetal Inflammatory Response Syndrome after Preterm Premature Rupture of Membranes.
- Pavcnik-Arnol M, Lucovnik M, Kornhauser-Cerar L, Premru-Srsen T, Hojker S, Derganc M.Author information Department of Paediatric Surgery and Intensive Care, University Medical Centre Ljubljana, Ljubljana, Slovenia.AbstractBackground: Intra-amniotic inflammation with preterm premature rupture of membranes (PPROM) is a risk factor for fetal inflammatory response syndrome (FIRS) and adverse neonatal outcome. Objectives: To evaluate the diagnostic accuracy of lipopolysaccharide-binding protein (LBP) for detecting FIRS in preterm neonates born after PPROM. Methods: This was a prospective study in the level III neonatal intensive care unit (42 neonates; 23 + 6 to 31 + 6 weeks' gestation) of mothers with PPROM. Umbilical cord blood concentrations of LBP, C-reactive protein (CRP), interleukin (IL)-6 and white blood cell count with differential were measured at delivery and 24 h after birth. Neonates were classified into FIRS (n = 22) and no FIRS (n = 20) groups according to clinical criteria and IL-6 level (≥17.5 pg/ml). Histological examination of the placenta and umbilical cord was performed. Neurological examination at 12 months' corrected age was performed. Results: Umbilical cord blood concentration of LBP was significantly higher in the FIRS group than in the no FIRS group at delivery (median 21.6 mg/l vs. median 2.3 mg/l; p < 0.0001) and 24 h after birth (median 17.2 mg/l vs. median 20.0 mg/l; p < 0.001). The area under the ROC curve for FIRS at delivery was 0.98 (95% CI 0.88-1.0) for LBP, 0.92 (95% CI 0.80-0.99) for CRP and 0.82 (95% CI 0.64-0.94) for immature to total neutrophil ratio. Similar results were obtained if FIRS was defined by funisitis. Umbilical cord blood concentration of LBP at delivery was significantly higher in neonates with abnormal neurological exam at 12 months than in those with normal exam (median 19.5 mg/l vs. median 3.75 mg/l; p < 0.015). Conclusions: In preterm neonates born to asymptomatic women with PPROM, LBP in cord blood at delivery is an excellent diagnostic biomarker of FIRS/funisitis with prognostic potential. © 2013 S. Karger AG, Basel.
- Neonatology.Neonatology.2013 Dec 11;105(2):121-127. [Epub ahead of print]
- Background: Intra-amniotic inflammation with preterm premature rupture of membranes (PPROM) is a risk factor for fetal inflammatory response syndrome (FIRS) and adverse neonatal outcome. Objectives: To evaluate the diagnostic accuracy of lipopolysaccharide-binding protein (LBP) for detecting FIRS in
- PMID 24335151
- Serial Neutrophil Values Facilitate Predicting the Absence of Neonatal Early-Onset Sepsis.
- Mikhael M1, Brown LS2, Rosenfeld CR3.Author information 1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical School, Dallas, TX.2Department of Health Systems Research, Parkland Health & Hospital System, Dallas, TX.3Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical School, Dallas, TX. Electronic address: charles.rosenfeld@utsouthwestern.edu.AbstractOBJECTIVE: To validate established neonatal neutrophil reference ranges (RRs) and determine the utility of serial measurements of neutrophil values in the first 24 hours to predict the absence of neonatal early-onset sepsis (EOS).
- The Journal of pediatrics.J Pediatr.2013 Dec 10. pii: S0022-3476(13)01376-0. doi: 10.1016/j.jpeds.2013.10.080. [Epub ahead of print]
- OBJECTIVE: To validate established neonatal neutrophil reference ranges (RRs) and determine the utility of serial measurements of neutrophil values in the first 24 hours to predict the absence of neonatal early-onset sepsis (EOS).STUDY DESIGN: Retrospective study of 2073 admissions to the neonatal i
- PMID 24331688
Japanese Journal
- 胆管結紮ラットにおける肝障害の進展に対する柴胡桂枝湯エキスの抑制効果--未熟ラットと成熟ラットでの比較
- 太田 好次,西村 むつみ,林 高弘 [他]
- 漢方と最新治療 19(2), 159-166, 2010-05
- NAID 40017144828
- 輸血・移植医療と臨床検査
- 西郷 勝康,橋本 誠,杉本 健 [他],炬口 真理子,井本 しおん,熊谷 俊一
- 臨床病理 56(3), 203-210, 2008-03-25
- NAID 10024356170
- 白血球機能制御による新たなる抗炎症治療戦略 : Granulocyte colony-stimulating factor (G-CSF) 療法
- 田中 裕,石川 和男,西野 正人,小倉 裕司,杉本 壽
- 炎症・再生 : 日本炎症・再生医学会雑誌 = Inflammation and regeneration 24(6), 619-628, 2004-11-25
- … It has been shown that G-CSF stimulates the proliferation and maturation of neutrophil precursor cells as well as increases such neutrophil functions as chemotaxis, phagocytosis, and bactericidal activity. …
- NAID 10026498694
Related Links
- im·ma·ture neu·tro·phil a young neutrophil; the term is usually used with reference to band (q.v.) or other "juvenile" neutrophils, which are neutrophilic ... 11); whereas in the fresh swim bladder group, there was mild inflammatory ...
- immature neutrophil Type: Term Definitions: 1. a young neutrophil; the term is usually used with reference to band (q.v.) or other “juvenile” neutrophils, which ... The definition information for immature neutrophil is provided by Stedman ...
Related Pictures
★リンクテーブル★
| リンク元 | 「幼若好中球」 |
| 関連記事 | 「immature」 |
「幼若好中球」
- 好中球系のすべての細胞から成熟好中球を除いたもので、分化、増殖能を有する未分化な好中球系前駆細胞
- 好中球系の骨髄芽球、前骨髄球、骨髄球、後骨髄球
- SIRSの診断基準の一つに「血液中の幼若好中球数>10%」がある。
「immature」
- adj.
- 未成熟の、未熟な