WordNet

a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
carbonated drink with fruit syrup and a little phosphoric acid
a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
an adrenal-cortex hormone (trade names Hydrocortone or Cortef) that is active in carbohydrate and protein metabolism (同)cortisol, Hydrocortone, Cortef

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/01/31 00:05:22」(JST)

Hydrocortisone sodium phosphate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.

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1. まれな先天性副腎過形成 uncommon congenital adrenal hyperplasias
2. 麻酔後回復室（PACU）における心血管の障害 cardiovascular problems in the post anesthesia care unit pacu
3. 成人における確定診断を得られていない低血圧やショックの評価および初期アプローチ evaluation of and initial approach to the adult patient with undifferentiated hypotension and shock
4. 小児における副腎不全の治療 treatment of adrenal insufficiency in children
5. 血清および唾液中のコルチゾールの測定 measurement of cortisol in serum and saliva

Miyashita T1, Kobayashi Z, Numasawa Y, Akaza M, Ishihara S, Shintani S.
Internal medicine (Tokyo, Japan).Intern Med.2012;51(13):1755-7. Epub 2012 Jul 1.
A 42-year-old man presented with fever, headache and liver dysfunction, and was diagnosed as having aseptic meningitis by lumbar puncture. The PCR detected Epstein-Barr virus (EBV)-DNA in the peripheral blood and cerebrospinal fluid. About 20 days after onset, the patient presented with hearing impa
PMID 22790140

'Empty sella syndrome': a case of a patient with sodium succinate hydrocortisone allergy.

Nucera E1, Lombardo C, Aruanno A, Colagiovanni A, Buonomo A, de Pasquale T, Pecora V, Sabato V, Rizzi A, Pascolini L, Ricci AG, Schiavino D.
European journal of endocrinology / European Federation of Endocrine Societies.Eur J Endocrinol.2011 Jan;164(1):139-40. doi: 10.1530/EJE-10-0863. Epub 2010 Oct 20.
OBJECTIVE: We present the case of a woman with 'empty sella syndrome' who experienced generalized urticaria after the administration of sodium succinate hydrocortisone in two episodes.METHODS: The patient underwent an allergological evaluation (prick, intradermal, and patch tests) with hydrocortison
PMID 20961968

Ferguson AD1, Emerson RM, English JS.
Contact dermatitis.Contact Dermatitis.2002 Dec;47(6):337-40.
Allergic contact dermatitis from topical corticosteroids is not uncommon. Budesonide has been included in the European standard series as a marker for corticosteroid allergy, though little is known of its cross-reactivity with other corticosteroids. Twelve patients previously positive to budesonide
PMID 12581279

Jung SP1, Siegrist B, Hornick CA, Wang YZ, Wade MR, Anthony CT, Woltering EA.
Angiogenesis.Angiogenesis.2002;5(1-2):111-8.
Tumor growth and metastasis are dependent on the development of new blood vessels. Inhibitors of new vessel growth have been widely investigated as anti-tumor agents. Endostatin, a 20 kDa C-terminal fragment of collagen XVIII inhibits endothelial cell proliferation, induces endothelial cell apoptosi
PMID 12549868

Miyashita Tomoyuki,Kobayashi Zen,Numasawa Yoshiyuki,Akaza Miho,Ishihara Shoichiro,Shintani Shuzo
Internal Medicine 51(13), 1755-1757, 2012
… The hearing acuity improved after the initiation of hydrocortisone sodium phosphate. …
NAID 130002062220

山村一彦,森田一郎,甲斐智朗 [他],堀内正敏
耳鼻咽喉科臨床 100(9), 757-760, 2007-09-01
… A 40-year-old male consulted our out-patient clinic due to right peripheral facial palsy.As soon as he was injected with the hydrocortisone sodium succinate, he developed erythema all over his body, moderate itchiness and respiratory distress. … Intradermal reaction was positive for three steroids with succinate-ester and negative for two steroids with phosphate-ester. …
NAID 10019531269

金子俊幸,伊藤照代,東海林徹,仲川義人
病院薬学 17(3), 108-117, 1991-06-20
… It has been considered that the admixtures of bromhexine hydrochloride and hydrocortisone sodium phosphate were incompatible in any infusions. …
NAID 110001798741

小宅正,青木路恵,望月真弓,村瀬勢津子,朝長文弥
病院薬学 16(6), 355-365, 1990-12-20
… In this study, the following steroids were used:hydrocortisone sodium succinate (HC), prednisolone sodium succinate (PS), methylprednisolone sodium succinate (MPS), dexamethasone disodium phosphate (DM), betamethasone disodium phosphate (BM) and flunisolide (FS). …
NAID 110001798706

リンク元	「hydrocortisone buteprate」「hydrocortisone succinate」「hydrocortisone aceponate」「hydrocortisone cypionate」「hydrocortisone acetate」
関連記事	「phosphate」「hydrocortisone」

Hydrocortisone sodium phosphate
Clinical data
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name Disodium [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate;
CAS Number	6000-74-4;
PubChem CID	441406;
UNII	0388G963HY;
Chemical and physical data
Formula	C21H31Na2O8P
Molar mass	488.42 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)COP(=O)([O-])[O-])O)C)O.[Na+].[Na+] ;
	InChI InChI=1S/C21H31O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h9,14-16,18,23,25H,3-8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14-,15-,16-,18+,19-,20-,21-;;/m0../s1 ; Key:RYJIRNNXCHOUTQ-OJJGEMKLSA-L ;