ヒドロコルチゾンブテプレート
- 関
- cortisol、hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
WordNet
- an adrenal-cortex hormone (trade names Hydrocortone or Cortef) that is active in carbohydrate and protein metabolism (同)cortisol, Hydrocortone, Cortef
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/05/03 14:57:07」(JST)
[Wiki en表示]
Hydrocortisone buteprate
|
Systematic (IUPAC) name |
(11β)-11-hydroxy-3,20-dioxo-21-(propionyloxy)pregn-4-en-17-yl butyrate |
Clinical data |
AHFS/Drugs.com |
monograph |
Pregnancy cat. |
C (US) |
Legal status |
OTC (US) |
Identifiers |
CAS number |
72590-77-3 |
ATC code |
D07AB11 |
PubChem |
CID 51627 |
Synonyms |
Hydrocortisone 17-butyrate 21-propionate |
Chemical data |
Formula |
C28H40O7 |
Mol. mass |
488.613 g/mol |
Y (what is this?) (verify) |
See also: hydrocortisone
Hydrocortisone buteprate is a topical steroid.[1][2] It is an ester of hydrocortisone (cortisol) with butyric acid and propionic acid.
References
- ^ Drugs.com: Hydrocortisone Buteprate topical
- ^ Sears, H. W.; Bailer, J. W.; Yeadon, A. (1997). "Efficacy and safety of hydrocortisone buteprate 0.1% cream in patients with atopic dermatitis". Clinical therapeutics 19 (4): 710–719. PMID 9377615. edit
Corticosteroids – glucocorticoids and mineralocorticoids (H02)
(also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B)
|
|
Mineralocorticoids
(3-one, 4-ene,
no FG at 16) |
- Pregnenedione: ALDOSTERONE
- 11-DEOXYCORTICOSTERONE
- HALOGENATED AT 9: Fludrocortisone
|
|
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy) |
Pregnene
|
|
|
Pregnenedione
(+20-one)
|
- HYDROCORTISONE/CORTISOL# (Hydrocortisone aceponate
- Hydrocortisone buteprate
- Hydrocortisone butyrate)
- Budesonide
- Ciclesonide
- Deflazacort
- Medrysone
- Tixocortol
- HALOGENATED AT 6: Cloprednol
- HALOGENATED, WITH FG AT 16: Halcinonide
|
|
Pregnadiene (+1-ene)
|
- Rimexolone
- HALOGENATED, WITH FG AT 16: Flunisolide
- Triamcinolone
- Amcinonide
- Fluocinolone acetonide (Fluocinonide)
|
|
Pregnadienediol
(+21-hydroxy)
|
- Prednisone (Meprednisone)
- HALOGENATED AT 9: Fluorometholone
- HALOGENATED, WITH FG AT 16: Fluocortolone (Clocortolone
- Diflucortolone
- Fluocortin)
- Desoximetasone
|
|
Pregnadienetriol
(+11-hydroxy)
|
- Prednisolone# (Methylprednisolone
- Methylprednisolone aceponate
- Prednicarbate
- Prednylidene)
- Desonide
- HALOGENATED: Fluprednisolone (Difluprednate
- Fluperolone)
- HALOGENATED, WITH FG AT 16: Dexamethasone#
- Betamethasone (Clobetasol
- Clobetasone
- Diflorasone
- Halometasone
- Ulobetasol)
- Beclometasone
- Paramethasone
- Alclometasone
- Fluclorolone acetonide
- Flumetasone
- Fluprednidene
|
|
Pregnatriene
(+2-ene)
|
|
|
Androstene
|
- HALOGENATED, WITH FG AT 16: Fluticasone (Fluticasone propionate
- Fluticasone furoate)
|
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Other/ungrouped
|
- HALOGENATED: Loteprednol
- HALOGENATED, WITH FG AT 16: Fludroxycortide
- Formocortal
- Mometasone furoate
|
|
|
Aldosterone antagonists |
- Spironolactone
- Eplerenone
- Potassium canrenoate
- Canrenone
|
|
Synthesis modifiers |
- Trilostane
- Carbenoxolone
- Aminoglutethimide
- Metyrapone
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
|
|
noco (d)/cong/tumr, sysi/epon
|
proc, drug (A10/H1/H2/H3/H5)
|
|
|
|
Glucocorticoids
|
|
Receptor |
|
|
Enzyme
(inhibitors) |
20,22-Desmolase
|
- 22-ABC
- 3,3′-Dimethoxybenzidine
- 3-Methoxybenzidine
- Aminoglutethimide
- Cyanoketone
- Danazol
- Etomidate
- Mitotane
- Trilostane
|
|
17α-Hydroxylase,
17,20-Lyase
|
- 22-ABC
- 22-Oxime
- Abiraterone
- Bifonazole
- Clotrimazole
- Cyanoketone
- Cyproterone
- Danazol
- Econazole
- Galeterone
- Gestrinone
- Isoconazole
- Ketoconazole
- L-39
- Liarozole
- LY-207,320
- MDL-27,302
- Miconazole
- Mifepristone
- Orteronel
- Pioglitazone
- Rosiglitazone
- Spironolactone
- Stanozolol
- SU-10,603
- TGF-β
- Tioconazole
- Troglitazone
- VN/87-1
- YM116
|
|
3β-HSD
|
- 4-MA
- Azastene
- Cyanoketone
- Danazol
- Epostane
- Genistein
- Gestrinone
- Metyrapone
- Norethisterone
- Oxymetholone
- Pioglitazone
- Rosiglitazone
- Trilostane
- Troglitazone
|
|
21-Hydroxylase
|
- Aminoglutethimide
- Amphenone B
- Bifonazole
- Clotrimazole
- Diazepam
- Econazole
- Genistein
- Isoconazole
- Ketoconazole
- Metyrapone
- Miconazole
- Midazolam
- Tioconazole
|
|
11β-Hydroxylase
|
- Aminoglutethimide
- Canrenone
- Etomidate
- Fadrozole
- FETO
- Ketoconazole
- Metomidate
- Metyrapone
- Mitotane
- Potassium canrenoate
- Spironolactone
- Trilostane
|
|
18-Hydroxylase
|
- Aminoglutethimide
- Canrenone
- FAD286
- Fadrozole
- Ketoconazole
- LCI699
- Metyrapone
- Mespirenone
- Potassium canrenoate
- Spironolactone
|
|
|
Other |
Endogenous
|
- Glucocorticoids: Corticosterone
- Cortisone
- Cortodoxone/Deoxycortisol
- Hydrocortisone/Cortisol
- Antiglucocorticoids: 17-Hydroxyprogesterone
- Deoxycorticosterone
- Pregnenolone
- Progesterone
- Precursors: Cholesterol
- 22R-Hydroxycholesterol
- 20α,22R-Dihydroxycholesterol
- Pregnenolone
- 17-Hydroxypregnenolone
- 17-Hydroxyprogesterone
- Progesterone
- Deoxycorticosterone
|
|
Indirect
|
- ACTH/Corticotropin
- CRH
- DHEA
- DHEA sulfate
- Plasma proteins (Transcortin, Albumin)
- Vasopressin
|
|
Procedures
|
- Adrenalectomy
- Hypophysectomy
|
|
|
UpToDate Contents
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English Journal
- Effect of a preceding laser dermabrasion on the outcome of combined therapy with narrowband ultraviolet B and potent topical steroids for treating nonsegmental vitiligo in resistant localizations.
- Bayoumi W1, Fontas E, Sillard L, Le Duff F, Ortonne JP, Bahadoran P, Lacour JP, Passeron T.
- The British journal of dermatology.Br J Dermatol.2012 Jan;166(1):208-11. doi: 10.1111/j.1365-2133.2011.10564.x. Epub 2011 Nov 17.
- BACKGROUND: The treatment of vitiligo remains unsatisfactory.OBJECTIVES: To assess in patients with vitiligo the effect of a laser dermabrasion in addition to the association of topical steroids and ultraviolet (UV) B in difficult-to-treat areas.METHODS: This was a single-centre prospective randomiz
- PMID 21824124
- Evaluation of sensory irritation caused by topical medications using a novel technique.
- Uliasz A1, Lebwohl M.
- International journal of dermatology.Int J Dermatol.2010 Mar;49(3):269-71. doi: 10.1111/j.1365-4632.2009.04219.x.
- BACKGROUND: Topical medications are often the first line therapy utilized by dermatologists for a variety of conditions. However, a common side effect of topical medications is application site irritation. The aim of this study was to evaluate and compare the sensory irritation caused by hydrocortis
- PMID 20465662
- Allergic contact dermatitis induced by topical hydrocortisone butyrate propionate mimicking acute generalized exanthematous pustulosis.
- TOHGI N, ETO H, MAEJIMA H, SAITO N, NAKAMURA M, KATSUOKA K.
- European journal of dermatology : EJD.Eur J Dermatol.2009 Sep-Oct;19(5):518-9. doi: 10.1684/ejd.2009.0744. Epub 2009 Jun 15.
- PMID 19527994
- Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial.
- Gong JQ1, Lin L, Lin T, Hao F, Zeng FQ, Bi ZG, Yi D, Zhao B.
- The British journal of dermatology.Br J Dermatol.2006 Oct;155(4):680-7.
- BACKGROUND: Staphylococcus aureus has a peculiar ability to colonize the skin of patients with eczema and atopic dermatitis (AD), and is consistently found in eczematous skin lesions in these patients. A correlation between the severity of the eczema and colonization with S. aureus has been demonstr
- PMID 16965415
Related Links
- Hydrocortisone buteprate is a topical steroid. It is an ester of hydrocortisone ( cortisol) with butyric acid and propionic acid. ... "Efficacy and safety of hydrocortisone buteprate 0.1% cream in patients with atopic dermatitis". Clinical therapeutics 19 ...
- Hydrocortisone Buteprate topical reference guide from the American Society of Health-System Pharmacists. Hydrocortisone Buteprate topical guidance for safe and effective use.
- Find patient medical information for hydrocortisone buteprate Top on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Related Pictures
![Description Hydrocortisone buteprate.png](https://1mg.info/0/g/u/1001.jpg)
![hydrocortisone buteprate hydrocortisone](https://1mg.info/0/g/u/1002.jpg)
![:Hydrocortisone buteprate.svg](https://1mg.info/0/g/u/1003.jpg)
![Hydrocortisone buteprate.svg](https://1mg.info/0/g/u/1004.jpg)
![File:Hydrocortisone buteprate.svg](https://1mg.info/0/g/u/1005.jpg)
![Description Hydrocortisone buteprate.svg](https://1mg.info/0/g/u/1006.jpg)
![File:Hydrocortisone buteprate.svg](https://1mg.info/0/g/u/1007.jpg)
★リンクテーブル★
[★]
- 関
- cortisol、hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium succinate、hydrocortisone succinate
[★]
- 関
- cortisol、hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate
[★]
ヒドロコルチゾンアセ・ネート
- 関
- hydrocortisone、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
[★]
- 関
- hydrocortisone、hydrocortisone aceponate、hydrocortisone acetate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
[★]
- 関
- hydrocortisone、hydrocortisone aceponate、hydrocortisone buteprate、hydrocortisone butyrate、hydrocortisone butyrate propionate、hydrocortisone cypionate、hydrocortisone sodium phosphate、hydrocortisone sodium succinate、hydrocortisone succinate
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