hemorrhagic disease of newborn

WordNet

1. an impairment of health or a condition of abnormal functioning
2. recently born; "a newborn infant"
3. having just or recently arisen or come into existence; "new nations"; "with newborn fears" (同)new-sprung
4. caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
5. of or relating to a hemorrhage (同)haemorrhagic

PrepTutorEJDIC

1. 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
2. (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
3. 女性の話術芸人 =diseur
4. 生まれたばかりの / 生まれ変わった,再生の
5. 病気にかかった / 病的な,不健全な(morbid)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/06 09:50:39」(JST)

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Not to be confused with Hemolytic disease of the newborn.

Haemorrhagic disease of the newborn
Vitamin K1
Classification and external resources
Specialty	pediatrics
ICD-10	P53
ICD-9-CM	776.0
DiseasesDB	29544
MedlinePlus	007320
eMedicine	ped/966
MeSH	D006475

Haemorrhagic disease of the newborn, also known as vitamin K deficiency bleeding (VKDB), is a coagulation disturbance in newborn infants due to vitamin K deficiency. As a consequence of vitamin K deficiency there is an impaired production of coagulation factors II, VII, IX, X, protein C and protein S by the liver, resulting in excessive bleeding (hemorrhage).

Signs and symptoms

The disease causes an increased risk of bleeding. The most common sites of bleeding are the umbilicus, mucous membranes, gastrointestinal tract, circumcision and venepunctures.

Causes

Newborns are relatively vitamin K deficient for a variety of reasons. They have low vitamin K stores at birth, vitamin K passes the placenta poorly, the levels of vitamin K in breast milk are low and the gut flora has not yet been developed (vitamin K is normally produced by intestinal bacteria).

Treatment

Treatment consists of vitamin K supplementation. This is often given prophylactically to newborns shortly after birth.

References

UpToDate Contents

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• 1. ビタミンKの概要 overview of vitamin k
• 2. 出血症状を有する小児に対するアプローチ approach to the child with bleeding symptoms
• 3. 小児における上部消化管出血に対するアプローチ approach to upper gastrointestinal bleeding in children
• 4. 健康な新生児のルーチンのマネージメントの概要 overview of the routine management of the healthy newborn infant
• 5. 全身性エリテマトーデスの神経精神症状：原因および診断的アプローチ lower gastrointestinal bleeding in children causes and diagnostic approach

English Journal

• Probable Interaction Between Warfarin and Banana Flakes Supplement.

• King AE1, Strnad K2.
• Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition.Nutr Clin Pract.2016 Feb;31(1):125-31. doi: 10.1177/0884533615591056. Epub 2015 Jul 2.
• PURPOSE: To describe a case of subtherapeutic international normalized ratio (INR) associated with concomitant use of warfarin and banana flakes in a patient with diarrhea.SUMMARY: A man in his 30s was hospitalized for an elective procedure, but his stay was complicated by cerebral venous thrombosis
• PMID 26137942

• Reasons for Refusal of Newborn Vitamin K Prophylaxis: Implications for Management and Education.

• Hamrick HJ1, Gable EK2, Freeman EH1, Dunn LL1, Zimmerman SP1, Rusin MM1, Linthavong OR1, Wright ME3, Moss LA4, Skinner AC5.
• Hospital pediatrics.Hosp Pediatr.2016 Jan;6(1):15-21. doi: 10.1542/hpeds.2015-0095.
• OBJECTIVE: The American Academy of Pediatrics recommends intramuscular (IM) vitamin K prophylaxis for all newborns to prevent vitamin K deficiency bleeding. Given the serious implications of late-onset vitamin K deficiency bleeding, our objective was to examine factors influencing parents' decisions
• PMID 26711469

Japanese Journal

• Intracranial hemorrhage : Clinical and demographic features of patients with late hemorrhagic disease

• PIRINCCIOGLU Ayfer Gozu,GURKAN Fuat,BOSNAK Mehmet,ACEMOGLU Hamit,DAVUTOGLU Mehmet
• Pediatrics international : official journal of
• NAID 10029557195

• ITP合併妊娠による胎児期脳室内出血後水頭症の1例

• 伊藤 英道,榊原 陽太郎,平本 準,吉田 浩,酒井 晃治,小野寺 英孝,和久井 大輔,田口 芳雄
• 脳神経外科ジャーナル 18(1), 56-61, 2009-01-20
• ITP合併妊娠による胎児脳室内出血後水頭症の1例を報告する.胎生34週に母体超音波にて胎児脳室内出血と頭囲拡大がみられ,35週に帝王切開にて出生.出生時,児の血小板数は1.7×10^4/μlで,血小板輸血,ガンマグロブリン大量療法,ステロイド療法を行った.生後3日目に血小板数は7.6×10^4/μlに増加し,水頭症に対しOmmayaリザーバー留置術を施行したところ,再び脳室内出血をきたした.保存的 …
• NAID 110007029865

Related Links

• Hemorrhagic Disease of Newborn: Background ...

In the past, the term hemorrhagic disease of the newborn was used to describe bleeding disorders in neonates associated with a traumatic birth or hemophilia. The proper diagnostic term that has been adopted is ...

• Vitamin K deficiency bleeding of the newborn: MedlinePlus ...

Centers for Disease Control and Prevention. Notes from the field: late vitamin K deficiency bleeding in infants whose parents declined vitamin K prophylaxis--Tennessee, 2013. MMWR Morb Mortal Wkly Rep. 2013;62(45 ...

Related Pictures

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★リンクテーブル★

リンク元	「新生児出血性疾患」
関連記事	「disease」「newborn」「hemorrhagic」

「新生児出血性疾患」

　　[★]

英

hemorrhagic disease of newborn, hemorrhagic disease of the newborn

関

新生女児性器出血

「disease」

　　[★]

• n.

疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)

特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)

• something that is very wrong with people's attitudes, way of life or with society.

関

ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness

• 注意

disease ≠ illness ≠ disorder

　 　 　

「newborn」

　　[★]

• n.

• 新生児

• adj.

• 新生児の

関

neonatal、neonate、newborn animal、newborn infant

　 　 　

「hemorrhagic」

　　[★]

• adj.

• 出血性の、易出血性の

関

haemophilic、haemorrhagic、hemophilic