WordNet

a substance that exerts some force or effect
a businessman who buys or sells for another in exchange for a commission (同)factor, broker
any agent or representative of a federal agency or bureau (同)federal agent
a representative who acts on behalf of other persons or organizations
an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
how long something has existed; "it was replaced because of its age"
a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
begin to seem older; get older; "The death of his wife caused him to age fast"
make older; "The death of his child aged him tremendously"
a calculus formed in the gall bladder or its ducts (同)bilestone
the process of going into solution; "the dissolving of salt in water" (同)dissolution

PrepTutorEJDIC

『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
胆石

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1. 偶発的胆石患者へのアプローチ approach to the patient with incidental gallstones
2. 胆石の溶解療法 dissolution therapy for the treatment of gallstones
3. 胆石の疫学および危険因子 epidemiology of and risk factors for gallstones
4. 成人における合併症のない胆石症 uncomplicated gallstone disease in adults
5. 胆石症の非外科的治療のための患者選択 patient selection for the nonsurgical treatment of gallstone disease

Preparation of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate in an anaerobic interface bioreactor.

Oda S1, Sugai T, Ohta H.
Journal of bioscience and bioengineering.J Biosci Bioeng.2001;91(2):202-7.
An interface bioreactor, which is a device for the microbial transformation of water-insoluble substrates, was applied to an anaerobic bioconversion for the first time. Methyl 7-ketolithocholate [Me-7KLCA] was reduced with the human intestinal bacterium Eubacterium aerofaciens JCM 7790 in a convenie
PMID 16232975

Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs.

Angelico M1, Mogavero L, Baiocchi L, Nistri A, Gandin C.
Scandinavian journal of gastroenterology.Scand J Gastroenterol.1995 Dec;30(12):1178-85.
BACKGROUND: Unconjugated bile salts currently available for gallstone dissolution are poorly effective. We evaluated in vitro the litholytic potency of taurine-amidated bile salts against human cholesterol gallstones.METHODS: Seventy radiolucent gallstones with similar size and composition (choleste
PMID 9053971

New 6-substituted bile acids: physico-chemical and biological properties of 6 alpha-methyl ursodeoxycholic acid and 6 alpha-methyl-7-epicholic acid.

Roda A1, Pellicciari R, Cerrè C, Polimeni C, Sadeghpour B, Marinozzi M, Forti GC, Sapigni E.
Journal of lipid research.J Lipid Res.1994 Dec;35(12):2268-79.
New analogs of ursodeoxycholic acid and 7-epicholic acid containing a 6 alpha-methyl group were synthesized, and their physico-chemical properties were studied and compared with those of their natural analogs. The 6 alpha-methyl group slightly increases the lipophilicity and slightly lowers the crit
PMID 7897324

Preparation of Methyl Ursodeoxycholate via Microbial Reduction of Methyl 7-Ketolithocholate in an Anaerobic Interface Bioreactor

Oda Shinobu,Sugai Takeshi,Ohta Hiromichi
Journal of bioscience and bioengineering 91(2), 202-207, 2001-02-25
… The resulting methyl ursodeoxycholate [Me-UDCA] is a precursor of ursodeoxycholic acid, which is used as a cholesterol gallstone-dissolving agent. …
NAID 110002683808

Preparation of Methyl Ursodeoxycholate via Microbial Reduction of Methyl 7-Ketolithocholate in an Anaerobic Interface Bioreactor.

ODA SHINOBU,SUGAI TAKESHI,OHTA HIROMICHI
Journal of Bioscience and Bioengineering 91(2), 202-207, 2001
… The resulting methyl ursodeoxycholate [Me-UDCA] is a precursor of ursodeoxycholic acid, which is used as a cholesterol gallstone-dissolving agent. …
NAID 130004145157

Absorption, Biliary Excretion, and Metabolism of a New Cholelitholytic Agent, Ursodeoxycholyl N-Carboxymethylglycine and Its Esters in Rats

HATONO Shunso,YOSHIDA Harumi,MATSUNAMI Masumi,IDE Yukako,MATSUDA Kaoru,YATSUNAMI Takashi,FUWA Tohru,KIHIRA Kenji,KURAMOTO Taiju,HOSHITA Takahiko
Journal of pharmacobio-dynamics 14(10), 561-566, 1991-10
… Intestinal absorption, biliary excretion and metabolism of a calcium gallstone dissolving agent, [11,12-^3H] ursodeoxycholyl-N-carboxymethylglycine (UDC-CMG) and its monoethyl, diethyl and dipivaloyloxyethyl esters (UDC-CMG-Et, UDC-CMG-Et_2 and UDC-CMG-PV_2) were studied in bile duct cannulated rats. … These results suggest the usefulness of UDC-CMG-PV_2 as the pro-drug in calcium gallstone dissolution therapy. …
NAID 110003655000