ferredoxin-NADP reductase

フェレドキシンNADP還元酵素

関

NADPH-ferredoxin reductase

WordNet

1. an enzyme that catalyses the biochemical reduction of some specified substance

UpToDate Contents

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• 1. ステロイド5 -α-レダクターゼ2欠乏症 steroid 5 alpha reductase 2 deficiency
• 2. メトヘモグロビン血症の遺伝学および病因 genetics and pathogenesis of methemoglobinemia
• 3. 糖尿病合併症の予防におけるアルドース還元酵素阻害剤 aldose reductase inhibitors in the prevention of diabetic complications
• 4. ヘキソースリン酸側路およびグルタチオン代謝疾患（グルコース-6-リン酸脱水素酵素欠損症を除く） disorders of the hexose monophosphate shunt and glutathione metabolism other than glucose 6 phosphate dehydrogenase deficiency
• 5. メトヘモグロビン血症の臨床的特徴、診断、および治療 clinical features diagnosis and treatment of methemoglobinemia

English Journal

• The C-terminal extension of bacterial flavodoxin-reductases: Involvement in the hydride transfer mechanism from the coenzyme.

• Bortolotti A, Sánchez-Azqueta A, Maya CM, Velázquez-Campoy A, Hermoso JA, Medina M, Cortez N.SourceInstituto de Biología Molecular y Celular de Rosario, Universidad Nacional de Rosario & CONICET, Rosario, Argentina.
• Biochimica et biophysica acta.Biochim Biophys Acta.2014 Jan;1837(1):33-43. doi: 10.1016/j.bbabio.2013.08.008. Epub 2013 Sep 6.
• To study the role of the mobile C-terminal extension present in bacterial class of plant type NADP(H):ferredoxin reductases during catalysis, we generated a series of mutants of the Rhodobacter capsulatus enzyme (RcFPR). Deletion of the six C-terminal amino acids beyond alanine 266 was combined with
• PMID 24016470

• The bidirectional NiFe-hydrogenase in Synechocystis sp. PCC 6803 is reduced by flavodoxin and ferredoxin and is essential under mixotrophic, nitrate-limiting conditions.

• Gutekunst K, Chen X, Schreiber K, Kaspar U, Makam S, Appel J.SourceChristian-Albrechts University, Germany;
• The Journal of biological chemistry.J Biol Chem.2013 Dec 5. [Epub ahead of print]
• Cyanobacteria are able to use solar energy for the production of hydrogen. It is generally accepted that cyanobacterial NiFe-hydrogenases are reduced by NAD(P)H. This is in conflict with thermodynamic considerations, as the midpoint potentials of NAD(P)H do not suffice to support the measured hydrog
• PMID 24311779

• Sulfolobus tokodaii ST2133 is characterized as a thioredoxin reductase-like ferredoxin:NADP+ oxidoreductase.

• Yan Z, Nam YW, Fushinobu S, Wakagi T.SourceDepartment of Biotechnology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
• Extremophiles : life under extreme conditions.Extremophiles.2013 Dec 1. [Epub ahead of print]
• The putative gene (st2133) for ferredoxin:NADP+ oxidoreductase (FNR) from Sulfolobus tokodaii, a thermoacidophilic crenarchaeon, was heterologously expressed. About 90 % of the purified product was a homodimer containing 0.46 mol FAD/mol subunit, and showing NADPH:DCPIP oxidoreductase activity, V
• PMID 24292509

Japanese Journal

• Replacement of Tyr50 stacked on the si-face of the isoalloxazine ring of the flavin adenine dinucleotide prosthetic group modulates Bacillus subtilis ferredoxin-NADP+ oxidoreductase activity toward NADPH

• Seo Daisuke,Naito Hiroshi,Nishimura Erika,Sakurai Takeshi
• Photosynthesis Research 125(1-2), 321-328, 2015-02-20
• … Ferredoxin-NAD(P)+ oxidoreductases ([EC 1.18.1.2], [EC 1.18.1.3], FNRs) from green sulfur bacteria, purple non-sulfur bacteria and most of Firmicutes, such as Bacillus subtilis (BsFNR) are homo-dimeric flavoproteins homologous to bacterial NADPH-thioredoxin reductase. …
• NAID 120005602822

• Role of the C-terminal extension stacked on the re-face of the isoalloxazine ring moiety of the flavin adenine dinucleotide prosthetic group in ferredoxin-NADP+ oxidoreductase from Bacillus subtilis

• Seo Daisuke,Asano Tomoya,Komori Hirofumi,Sakurai Takeshi
• Plant Physiology and Biochemistry 81, 143-148, 2014-08
• … Ferredoxin-NADP+ oxidoreductase [EC 1.18.1.2] from Bacillus subtilis (BsFNR) is homologous to the bacterial NADPH-thioredoxin reductase, but possesses a unique C-terminal extension that covers the re-face of the isoalloxazine ring moiety of the flavin adenine dinucleotide (FAD) prosthetic group. …
• NAID 120005411656

• 2P256 ガリウム置換フェレドキシンの結晶構造とPS1およびFNRとの相互作用部位(18B.光生物:光合成,ポスター,日本生物物理学会年会第51回(2013年度))

• Mutoh Risa,Muraki Norifumi,Kubota-Kawai Hisako,Hase Toshiharu,Ikegami Takahisa,Kurisu Genji
• 生物物理 53(SUPPLEMENT_1-2), S201, 2013-09-13
• NAID 110009819744

Related Links

• Ferredoxin—NADP(+) reductase | Facebook

Ferredoxin—NADP(+) reductase. 0 likes · 0 talking about this. NomenclatureThe systematic name of this enzyme class is ferredoxin:NADP oxidoreductase. Other names in common use include: adrenodoxin reductase, ferredoxin ...

• DrugBank: Ferredoxin--NADP reductase

General Function Involved in oxidoreductase activity Specific Function Reduced ferredoxin + NADP(+) = oxidized ferredoxin + NADPH Pathways Not Available Reactions Not Available Pfam Domain Function FAD_binding_1 (PF00667 ) ...

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★リンクテーブル★

リンク元	「フェレドキシンNADP還元酵素」「NADPH-ferredoxin reductase」
関連記事	「NA」「reductase」「NAD」「NADP」「ferredoxin」

「フェレドキシンNADP還元酵素」

　　[★]

英

ferredoxin-NADP reductase

関

NADPHフェレドキシン還元酵素

「NADPH-ferredoxin reductase」

　　[★]

NADPHフェレドキシン還元酵素

関

ferredoxin-NADP reductase

「NA」

　　[★]

• ノルアドレナリン, noradrenaline
• ノイラミニダーゼ, neur-aminidase
• Narcotics Anonymous
• ナリジクス酸 nalidixic acid

「reductase」

　　[★]

• n.

(酵素)還元酵素、レダクターゼ、リダクターゼ

関

dehydrogenase、oxidase、oxidoreductase、reducing enzyme

　

「NAD」

　　[★]

• ニコチンアミドアデニンジヌクレオチド nicotinamide adenine dinucleotide
• 異常所見なし nothing abnormal detected

「NADP」

　　[★] ニコチンアミドアデニンジヌクレオチドリン酸 nicotinamide adenine dinucleotide phosphate

「ferredoxin」

　　[★]

フェレドキシン

関

Fd