extremely drug-resistant

• 極度薬剤耐性の

WordNet

1. most distant in any direction; "the extreme edge of town"
2. the furthest or highest degree of something; "he carried it to extremes"
3. of the greatest possible degree or extent or intensity; "extreme cold"; "extreme caution"; "extreme pleasure"; "utmost contempt"; "to the utmost degree"; "in the uttermost distress" (同)utmost, uttermost
4. beyond a norm in views or actions; "an extreme conservative"; "an extreme liberal"; "extreme views on integration"; "extreme opinions"
5. far beyond a norm in quantity or amount or degree; to an utmost degree; "an extreme example"; "extreme temperatures"; "extreme danger"
6. use recreational drugs (同)do drugs
7. administer a drug to; "They drugged the kidnapped tourist" (同)dose
8. a substance that is used as a medicine or narcotic
9. impervious to being affected; "resistant to the effects of heat"; "resistant to persuasion"
10. to an extreme degree; "extremely cold"; "extremely unpleasant" (同)exceedingly, super, passing

PrepTutorEJDIC

1. 《名詞の前にのみ用いて》『極度の』,はなはだしい / 『いちばん端の』,最も遠い / 極端な,過激な / 月並みでない,異常な / (程度・位置などが)両極端にあるものの一方 / 極度;《しばしば復数形で》行き過ぎ,過渡 / 《しばしば復数形で》思い切った処置,徹底的な手段 / (数学で)外項(a:b=c:dのaとb);極値
2. 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
3. 抵抗力のある;(…に)抵抗する《+『to』+『名』》
4. 『極端に』,非常に過度に

UpToDate Contents

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• 1. アルコールおよびその他の薬物の有害な使用のスクリーニング screening for unhealthy use of alcohol and other drugs
• 2. 抗マラリア剤：概要 antimalarial drugs an overview
• 3. 薬剤耐性結核の疫学および分子メカニズム epidemiology and molecular mechanisms of drug resistant tuberculosis
• 4. 統合失調症に対する薬物療法：持効性抗精神病薬注射製剤 pharmacotherapy for schizophrenia long acting injectable antipsychotic drugs
• 5. リウマチ性疾患を有する男性における抗炎症剤および免疫抑制剤が性腺機能に及ぼす影響 effects of antiinflammatory and immunosuppressive drugs on gonadal function in men with rheumatic diseases

English Journal

• Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide.

• Tyagi P1, Dharmaraja AT2, Bhaskar A3, Chakrapani H4, Singh A5.
• Free radical biology & medicine.Free Radic Biol Med.2015 Jul;84:344-54. doi: 10.1016/j.freeradbiomed.2015.03.008. Epub 2015 Mar 27.
• Mycobacterium tuberculosis (Mtb) has evolved protective and detoxification mechanisms to maintain cytoplasmic redox balance in response to exogenous oxidative stress encountered inside host phagocytes. In contrast, little is known about the dynamic response of this pathogen to endogenous oxidative s
• PMID 25819161

• Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: Preparation, in vitro and in vivo evaluation.

• He Z1, Schulz A2, Wan X1, Seitz J3, Bludau H2, Alakhova DY1, Darr DB4, Perou CM4, Jordan R5, Ojima I6, Kabanov AV7, Luxenhofer R8.
• Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2015 Jun 28;208:67-75. doi: 10.1016/j.jconrel.2015.02.024. Epub 2015 Feb 26.
• The clinically and commercially successful taxanes, paclitaxel and docetaxel suffer from two major drawbacks, namely their very low aqueous solubility and the risk of developing resistance. Here, we present a method that overcomes both drawbacks in a very simple manner. We formulated 3rd generation
• PMID 25725361

• Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20.

• Agniswamy J1, Louis JM2, Shen CH1, Yashchuk S3, Ghosh AK3, Weber IT1.
• Journal of medicinal chemistry.J Med Chem.2015 Jun 25;58(12):5088-95. doi: 10.1021/acs.jmedchem.5b00474. Epub 2015 Jun 4.
• An extremely drug resistant mutant of HIV-1 protease (PR) bearing 20 mutations (PR20) has been studied with two potent antiviral investigational inhibitors. GRL-5010A and GRL-4410A were designed to introduce hydrogen bond interactions with the flexible flaps of the PR by incorporating gem-difluorine
• PMID 26010498

Japanese Journal

• Molecular epidemiology and characterization of genotypic analysis of <i>Acinetobacter baumannii</i> strains isolates from south China

• Japanese Journal of Infectious Diseases advpub(0), 2015
• NAID 130005086985

• アスペルギルス性感染性心内膜炎に対し三尖弁置換術および長期抗真菌薬投与を行い救命し得た1例

• 日本心臓血管外科学会雑誌 44(3), 151-154, 2015
• NAID 130005078169

• Advantages by Vagus Nerve Stimulation Therapy in Patient in Medically Refractory Epilepsy Based on Analysis of Direct Medical Cost of One General Hospital in Japan

• レギュラトリーサイエンス学会誌 5(2), 111-120, 2015
• NAID 130005077621

Related Links

• Extremely Drug Resistant Tuberculosis XDR-TB - VOA Story

U.S. health officials have quarantined an airline passenger who may have exposed others to a potentially dangerous form of tuberculosis. The unusual decision was made after the passenger took flights from the U.S. to Europe, then to Montreal, Canada before reentering the United States.

• Extremely drug-resistant TB [XDRTB]

multidrug-resistant tuberculosis (MDR-TB) but more extreme in its manifestation, it arises when common tuberculosis goes untreated or standard TB drugs are misused. James photographs represent these varying strains.

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★リンクテーブル★

リンク元	「極度薬剤耐性」
拡張検索	「extremely drug-resistant tuberculosis」
関連記事	「extreme」「extremely」「resistant」「drug」

「極度薬剤耐性」

　　[★]

英

extremely drug-resistant

「extremely drug-resistant tuberculosis」

　　[★]

極度薬剤耐性結核、極度薬剤耐性結核菌

関

extensively drug-resistant tuberculosis、XDR-TB、XXDR-TB

「extreme」

　　[★]

• adj.

• 極度な、極端な

Although diarrhea and constipation may present as mere nuisance symptoms at one extreme, they can be severe or life-threatening at the other.(HIM.246)(極端な例では単にやっかいな症状として出現することがあるが、もう一方の極端な場合、重篤で生命に危険を及ぼすことがありうる)

関

enormous、extremely、impossibly

　 　 　 　 　 　

「extremely」

　　[★]

• adv.

• 極度に、極端に、非常に

関

enormous、enormously、exceedingly、extraordinarily、extreme、greatly、immensely、impossibly、tremendously、very

　 　

「resistant」

　　[★]

• adj.

• 抵抗性の、耐性の、抵抗する

関

recalcitrance、refractory、resist、resistance、resistive、stand、tolerance、tolerant、withstand

　 　

「drug」

　　[★]

同

drugs