肝外胆汁うっ滞
- 関
- extrahepatic bile duct obstruction
UpToDate Contents
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English Journal
- Expression of renal Oat5 and NaDC1 transporters in rats with acute biliary obstruction.
- Brandoni A1, Torres AM1.
- World journal of gastroenterology : WJG.World J Gastroenterol.2015 Aug 7;21(29):8817-25. doi: 10.3748/wjg.v21.i29.8817.
- AIM: To examine renal expression of organic anion transporter 5 (Oat5) and sodium-dicarboxylate cotransporter 1 (NaDC1), and excretion of citrate in rats with acute extrahepatic cholestasis.METHODS: Obstructive jaundice was induced in rats by double ligation and division of the common bile duct (BDL
- PMID 26269671
- SIRT1/PGC-1α signaling protects hepatocytes against mitochondrial oxidative stress induced by bile acids.
- Tan M1, Tang C, Zhang Y, Cheng Y, Cai L, Chen X, Gao Y, Deng Y, Pan M.
- Free radical research.Free Radic Res.2015 Aug;49(8):935-45. doi: 10.3109/10715762.2015.1016020. Epub 2015 Mar 19.
- Oxidative stress and mitochondrial dysfunction are hypothesized to contribute to the pathogenesis of chronic cholestatic liver diseases. Silent information regulator 1 (SIRT1) attenuates oxidative stress and improves mitochondrial biogenesis in numerous mitochondrial-related diseases; however, a fun
- PMID 25789761
- Comparison of phenobarbitone and ursodeoxycholic acid in drug-augmented hepatobiliary scintigraphy for excluding the diagnosis of obstructive cholestasis in neonatal cholestasis syndrome.
- Malik D1, Khan SH, Ali SW, Rather TA, Pakala R, Hassan MU, Yadav N, Pasupula M.
- Nuclear medicine communications.Nucl Med Commun.2015 Aug;36(8):827-32. doi: 10.1097/MNM.0000000000000322.
- OBJECTIVES: Neonatal cholestasis is a common cause of jaundice among newborns. Hepatobiliary scintigraphy plays an important role in the diagnosis of neonatal cholestasis by ruling out extrahepatic biliary atresia, which is one of the common causes. Phenobarbitone and ursodeoxycholic acid (UDCA) hav
- PMID 25920049
Japanese Journal
- NEW METHOD OF COVERED WALLSTENTS FOR DISTAL MALIGNANT BILIARY OBSTRUCTION TO REDUCE EARLY STENT-RELATED COMPLICATIONS BASED ON CHARACTERISTICS
- NAKAI YOUSUKE,ISAYAMA HIROYUKI,TOGAWA OSAMU,KOGURE HIROFUMI,TSUJINO TAKESHI,YAGIOKA HIROSHI,YASHIMA YOKO,SASAKI TAKASHI,ITO YUKIKO,MATSUBARA SABURO,HIRANO KENJI,SASAHIRA NAOKI,TODA NOBUO,TADA MINORU,KAWABE TAKAO,OMATA MASAO,KOIKE KAZUHIKO
- Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 23(1), 49-55, 2011-01-01
- NAID 10028188306
- Alteration of Methotrexate Biliary and Renal Elimination during Extrahepatic and Intrahepatic Cholestasis in Rats
- Brcakova Eva,Fuksa Leos,Cermanova Jolana,Kolouchova Gabriela,Hroch Milos,Hirsova Petra,Martinkova Jirina,Staud Frantisek,Micuda Stanislav
- Biological & Pharmaceutical Bulletin 32(12), 1978-1985, 2009
- … Therefore, the aim of this study was to evaluate changes in MTX biliary and renal excretion during either intrahepatic or obstructive cholestasis in rats. … In conclusion, this study is the first describing marked alteration of MTX hepatic and renal elimination induced by cholestasis in rats. …
- NAID 130000116982
Related Links
- extrahepatic cholestasis, cholestasis occurring outside the liver, caused by blockage of a bile duct or ducts. It may be caused by a tumor or stricture, a ... Disclaimer All content on this website, including dictionary, thesaurus ...
- What is Extrahepatic Cholestasis Extrahepatic cholestasis excrete bile dysfunction of the liver cells, the inhibition of the secretion of bile or bile flow disorders (such as bile duct channel obstruction), causing bile to reach the ...
★リンクテーブル★
[★]
- 英
- obstructive jaundice
- 同
- 外科的黄疸 surgical jaundice、機械的黄疸 mechanical jaundice、肝外胆汁うっ滞症 extrahepatic cholestasis
- 関
- 黄疸、高ビリルビン血症
原因
病態
- 直接ビリルビンの胆汁としての排泄が減少 → (1)直接ビリルビンの血管への漏出、尿中へのビリルビンの出現、(2)疎水性ビタミンの吸収低下(ビタミンK欠乏による凝固低下)
検査
- 手順：スクリーニング検査(尿検査、便検査、血算、血液検査) → 超音波検査
尿検査
超音波検査
心電図
- 閉塞性黄疸では徐脈になるらしい。高ビリルビン血症による心筋伝導系障害のためらしい。
[★]
肝外胆管閉塞
- 関
- extrahepatic biliary obstruction、extrahepatic cholestasis
[★]
- 英
- extrahepatic cholestasis
- 関
- 閉塞性黄疸、胆汁うっ滞
[★]
- 英
- extrahepatic cholestasis
- 関
- 肝外胆管閉塞
[★]
- 関
- extrahepatically、nonhepatic