WordNet

without unnecessary stops; "an express train"; "an express shipment"
rapid transport of goods (同)expressage
public transport consisting of a fast train or bus that makes only a few scheduled stops; "he caught the express to New York" (同)limited
mail that is distributed by a rapid and efficient system (同)express mail
give expression to; "She showed her disappointment" (同)show, evince
indicate through a symbol, formula, etc.; "Can you express this distance in kilometers?" (同)state
articulate; either verbally or with a cry, shout, or noise; "She expressed her anger"; "He uttered a curse" (同)verbalize, verbalise, utter, give tongue to
by express; "please send the letter express"
manifest the effects of (a gene or genetic trait); "Many of the laboratory animals express the trait"
not tacit or implied; "her express wish"
send by rapid transport or special messenger service; "She expressed the letter to Florida"
the organic process of synthesizing and releasing some substance (同)secernment
a functionally specialized substance (especially one that is not a waste) released from a gland or cell
communicated in words; "frequently uttered sentiments" (同)uttered, verbalized, verbalised

PrepTutorEJDIC

(言葉で)〈思想・感情など〉‘を'『表現する』,言い表す,述べる / (言葉以外で)…‘を'『示す』,表す(indicate);〈数字・記号・式などが〉…‘を'表す / 《英》〈荷物など〉‘を'至急便で送る / (…から)〈果汁など〉‘を'絞り出す《+『名』+『from』+『名』》 / 特別の,特定の / はっきりした,明白な / 『至急便の』,急行の / 至急便で,急行で / 〈U〉(手紙・荷物などの)『至急便』 / 〈C〉(至急便を扱う)通運会社 / 〈C〉(列車・バスなどの)『急行』
〈C〉分泌(ぶんぴつ)作用(過程) / 〈C〉分泌物 / 〈U〉(…を)隠すこと《+『of』+『名』》

UpToDate Contents

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1. 慢性細菌性前立腺炎 chronic bacterial prostatitis
2. 慢性前立腺炎/慢性骨盤痛症候群 chronic prostatitis chronic pelvic pain syndrome
3. クラミジア・トラコマティス感染症の臨床症状および診断 clinical manifestations and diagnosis of chlamydia trachomatis infections
4. 急性細菌性前立腺炎 acute bacterial prostatitis
5. 男性の性交時痛 male dyspareunia

English Journal

Expressed Prostatic Secretion Biomarkers Improve Stratification of NCCN Active Surveillance Candidates: Performance of Secretion Capacity and TMPRSS2:ERG Models.

Whelan C1, Kawachi M1, Smith DD2, Linehan J1, Babilonia G1, Mejia R3, Wilson T1, Smith SS4.Author information 1Division of Urology, City of Hope, Duarte, California.2Division of Biostatistics, City of Hope, Duarte, California.3Clinical Research Information Support, City of Hope, Duarte, California.4Division of Urology, City of Hope, Duarte, California; Beckman Research Institute, City of Hope, Duarte, California. Electronic address: ssmith@coh.org.AbstractPURPOSE: Active surveillance is a viable patient option for prostate cancer provided that a clinical determination of low risk and presumably organ confined disease can be made. To standardize risk stratification schemes the NCCN (National Comprehensive Cancer Network®) provides guidelines for the active surveillance option. We determined the effectiveness of expressed prostatic secretion biomarkers for detecting occult risk factors in NCCN active surveillance candidates.
The Journal of urology.J Urol.2014 Jan;191(1):220-6. doi: 10.1016/j.juro.2013.05.019. Epub 2013 May 10.
PURPOSE: Active surveillance is a viable patient option for prostate cancer provided that a clinical determination of low risk and presumably organ confined disease can be made. To standardize risk stratification schemes the NCCN (National Comprehensive Cancer Network®) provides guidelines for the
PMID 23669563

A new role for Hedgehogs in juxtacrine signaling.

Pettigrew CA1, Asp E2, Emerson CP Jr3.Author information 1Boston Biomedical Research Institute, 64 Grove Street, Watertown, 02472 MA, USA; University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, 01655 MA, USA.2Boston Biomedical Research Institute, 64 Grove Street, Watertown, 02472 MA, USA.3Boston Biomedical Research Institute, 64 Grove Street, Watertown, 02472 MA, USA; University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, 01655 MA, USA. Electronic address: Charles.Emersonjr@umassmed.edu.AbstractThe Hedgehog pathway plays important roles in embryonic development, adult stem cell maintenance and tumorigenesis. In mammals these effects are mediated by Sonic, Desert and Indian Hedgehog (Shh, Dhh and Ihh). Shh undergoes autocatalytic cleavage and dual lipidation prior to secretion and forming a response gradient. Post-translational processing and secretion of Dhh and Ihh ligands has not previously been investigated. This study reports on the synthesis, processing, secretion and signaling activities of SHH, IHH and DHH preproteins expressed in cultured cells, providing unexpected evidence that DHH does not undergo substantial autoprocessing or secretion, and does not function in paracrine signaling. Rather, DHH functions as a juxtacrine signaling ligand to activate a cell contact-mediated HH signaling response, consistent with its localised signaling in vivo. Further, the LnCAP prostate cancer cell, when induced to express endogenous DHH and SHH, is active only in juxtacrine signaling. Domain swap studies reveal that the C-terminal domain of HH regulates its processing and secretion. These findings establish a new regulatory role for HHs in cell-mediated juxtacrine signaling in development and cancer.
Mechanisms of development.Mech Dev.2013 Dec 14. pii: S0925-4773(13)00099-3. doi: 10.1016/j.mod.2013.12.002. [Epub ahead of print]
The Hedgehog pathway plays important roles in embryonic development, adult stem cell maintenance and tumorigenesis. In mammals these effects are mediated by Sonic, Desert and Indian Hedgehog (Shh, Dhh and Ihh). Shh undergoes autocatalytic cleavage and dual lipidation prior to secretion and forming a
PMID 24342078

Male Infertility Workup Needs Additional Testing of Expressed Prostatic Secretion and/or Post-Massage Urine.

Punab M1, Kullisaar T2, Mändar R3.Author information 1Andrology Centre, Tartu University Hospital, Tartu, Estonia.2Department of Biochemistry, University of Tartu, Tartu, Estonia.3Department of Microbiology, University of Tartu, Tartu, Estonia.AbstractThe male factor accounts for almost 50% of infertility cases. Inflammation may reduce semen quality via several pathways, including oxidative stress (OxS). As male infertility routinely is assessed using semen analysis only, the possible presence of non-leukocytospermic asymptomatic inflammatory prostatitis may be overlooked. We compared local and systemic OxS levels in male partners of infertile couples with different inflammation patterns in their genital tract and/or oligospermia. Subjects (n=143) were grouped according to inflammation in their semen, expressed prostatic secretion (EPS), and/or post-massage urine (post-M). Systemic (8-isoprostanes in urine) and local (diene conjugates and total antioxidant capacity in seminal plasma) OxS was measured The levels of OxS markers were significantly elevated in both severe inflammation groups - leukocytospermic men and subjects whose inflammation was limited only to EPS and/or post-M. Comparison between oligospermic and non-oligospermic men with genital tract inflammation, and oligozoospermic men with or without inflammation in the genital tract indicated that inflammation but not oligospermia status had significant impact on the measured OxS markers. Hence, a high leukocyte count in prostate-specific materials (EPS, post-M), even in absence of clear leukocytopsermia, is an important source of local and systemic OxS that may be associated with male infertility and affect general health. We suggest including the tests for detection of inflammation of the prostate into the workup of infertile men as was suggested in the WHO 1993 recommendation.
PloS one.PLoS One.2013 Dec 9;8(12):e82776. doi: 10.1371/journal.pone.0082776.
The male factor accounts for almost 50% of infertility cases. Inflammation may reduce semen quality via several pathways, including oxidative stress (OxS). As male infertility routinely is assessed using semen analysis only, the possible presence of non-leukocytospermic asymptomatic inflammatory pro
PMID 24349358

Japanese Journal

分泌物検査 (泌尿器科検査のここがポイント) -- (尿検査)

高橋聡
臨床泌尿器科 64(4), 74-76, 2010-04
NAID 40017066145

前立腺炎におけるlevofloxacinの臨床効果と尿中あるいは前立腺圧出液中のサイトカインの変動

松井隆,李勝,酒井豊,米本洋次,中野雄造,樋口彰宏,宮崎茂典,郷司和男,岡田弘,荒川創一,守殿貞夫
日本化学療法学会雜誌 = Japanese journal of chemotherapy 47(2), 89-96, 1999-02-25
NAID 10005865016

Clinical study on levofloxacin for prostatitis and cytokines in urine or expressed prostatic secretion of prostatitis patients.

松井隆,李勝,酒井豊,米本洋次,中野雄造,樋口彰宏,宮崎茂典,郷司和男,岡田弘,荒川創一,守殿貞夫
日本化学療法学会雑誌 47(2), 89-96, 1999
The clinical efficacy and safety of levofloxacin (LVFX) were evaluated in 19 patients with acute bacterial, chronic bacteirial or chronic non-bacterial prostatitis (ABP, CBP, CNP). We measured urinary …
NAID 130004297905