estrogen response element

同

(ERE

WordNet

1. a straight line that generates a cylinder or cone
2. one of four substances thought in ancient and medieval cosmology to constitute the physical universe; "the alchemists believed that there were four elements"
3. the situation in which you are happiest and most effective; "in your element"
4. the most favorable environment for a plant or animal; "water is the element of fishes"
5. a result; "this situation developed in response to events in Africa"
6. a phrase recited or sung by the congregation following a versicle by the priest or minister
7. the manner in which an electrical or mechanical device responds to an input signal or a range of input signals
8. a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics (同)oestrogen
9. violent or severe weather (viewed as caused by the action of the four elements); "they felt the full fury of the elements"

PrepTutorEJDIC

1. 〈C〉(物質を構成する)元素 / 〈C〉《修飾語[句]を伴って》(…の)(基本的な)『要素』,『成分』;《しばしば複数形で》構成分子 / 〈C〉(生物に固有の)生息場所,環境;(人の)適所,本領 / 〈C〉《古》四大(しだい)[元素](自然界の基本的構成要素と考えられていた地(earth)・水(water)・風(air)・火(fire)の4大要素の一つ) / 《the elements》(雨・風・雪などの)自然力・風雨,(特に)悪天候 / 《the elements》(学問の)原理,初歩,概論
2. 〈C〉(…に対する)『返事』,『返答』《+『to』+『名』》 / 〈C〉〈U〉(…に対する)『反応』,『反響』《『to』+『名』》 / 〈C〉応答歌,応唱(牧師にならって合唱隊・会衆が短い祈り・歌を応答すること)
3. エストロゲン(動物の雌を発情させる卵胞ホルモン)(《英》oestrogen)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/02 20:54:18」(JST)

wiki en

[Wiki en表示]

A hormone response element (HRE) is a short sequence of DNA within the promoter of a gene that is able to bind a specific hormone receptor complex and therefore regulate transcription. The sequence is most commonly a pair of inverted repeats separated by three nucleotides, which also indicates that the receptor binds as a dimer. Specifically, HRE responds to steroid hormones, as the activated steroid receptor is the transcription factor binding HRE. This regulates the transcription of genes signaled by the steroid hormone.

A gene may have many different response elements, allowing complex control to be exerted over the level and rate of transcription.

HRE are used in transgenic animal cells as inducers of gene expression.

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 選択的エストロゲン受容体モジュレーターの作用機序 mechanisms of action of selective estrogen receptor modulators
• 2. エストロゲン作用の分子生物学および生理学 molecular biology and physiology of estrogen action
• 3. エストロゲン・プロゲスチン避妊剤の使用に関する概要 overview of the use of estrogen progestin contraceptives
• 4. 転移性ホルモン受容体陽性乳癌に対する治療アプローチ：内分泌療法 treatment approach to metastatic hormone receptor positive breast cancer endocrine therapy
• 5. 骨粗鬆症の予防および治療のための選択的エストロゲン受容体調節剤 selective estrogen receptor modulators for prevention and treatment of osteoporosis

English Journal

• Conservative nature of oestradiol signalling pathways in the brain lobes of Octopus vulgaris involved in reproduction, learning and motor coordination.

• De Lisa E, Paolucci M, Di Cosmo A.SourceDepartment of Structural and Functional Biology, University of Napoli "Federico II", Via Cinthia, 80126 Napoli, Italy. Department of Biological, Geological and Environmental Sciences, University of Sannio, Via Port'Arsa, 82100 Benevento, Italy.
• Journal of neuroendocrinology.J Neuroendocrinol.2011 Oct 11. doi: 10.1111/j.1365-2826.2011.02240.x. [Epub ahead of print]
• Oestradiol plays in the mammalian brain crucial roles by modulating reproductive behaviour, neural plasticity and pain perception. The cephalopod Octopus vulgaris is considered, along with its relatives, the most behaviourally advanced invertebrate, although the neurophysiological basis of its behav
• PMID 21988192

• Does a nonclassical signaling mechanism underlie an increase of estradiol-mediated gonadotropin-releasing hormone receptor binding in ovine pituitary cells?

• Davis TL, Whitesell JD, Cantlon JD, Clay CM, Nett TM.SourceAnimal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado.
• Biology of reproduction.Biol Reprod.2011 Oct;85(4):770-8. Epub 2011 Jul 6.
• Estradiol-17beta (E2) is the major regulator of GnRH receptor (GnRHR) gene expression and number during the periovulatory period; however, the mechanisms underlying E2 regulation of the GNRHR gene remain undefined. Herein, we find that E2 conjugated to BSA (E2-BSA) mimics the stimulatory effect of E
• PMID 21734267

Japanese Journal

• P2-32 estrogen response element付加による癌抑制遺伝子p53の発現促進(Group37 子宮体部悪性腫瘍5,一般演題,第61回日本産科婦人科学会学術講演会)

• 梶谷 耕二,本田 謙一,安部 佳代子,中野 雄介,吉田 愛,吉田 裕之,市村 友季,松本 佳也,角 俊幸,金岡 靖,石河 修
• 日本産科婦人科學會雜誌 61(2), 536, 2009-02-01
• NAID 110007167621

• Cell Growth of Ovarian Cancer Cells is Stimulated by Xenoestrogens through an Estrogen-Dependent Pathway, but Their Stimulation of Cell Growth Appears not to be Involved in the Activation of the Mitogen-Activated Protein Kinases ERK-1 and p38

• PARK Se-Hyung,KIM Ki-Yon,AN Beum-Soo,CHOI Jung-Hye,JEUNG Eui-Bae,LEUNG Peter C. K.,CHOI Kyung-Chul
• The Journal of reproduction and development 55(1), 23-29, 2009-02-01
• … Thus, in this study, we evaluated the effects of EDCs on proliferation and regulation of transcription of estrogen receptor (ER)-positive BG-1 ovarian cancer cells, and their possible mechanisms were further examined. … Treatment with BPA, NP, OP and MXC increased the estrogen response element (ERE) activity. … The increase of cell proliferation and activation of ERE were reversed in the presence of an estrogen receptor antagonist, ICI 182780. …
• NAID 10024940821

Related Links

• Response Elements

Response Element, Transcription Factor, Consensus Sequence. CRE, CREB, TGACGTCA. ERE, Estrogen receptor, AGGTCANNNTGACCT. GRE, Glucocorticoid receptor, AGAACANNNTGTTCT. HSE, Heat shock factor, GAANNTTCNNGAA ...

Related Pictures

---

★リンクテーブル★

リンク元	「応答配列」「ERE」
関連記事	「element」「response」

「応答配列」

　　[★]

英

responsive element, response element

関

estrogen response element, cyclic AMP response element

「ERE」

　　[★]

関

estrogen response element

「element」

　　[★]

• n.

• 要素、成分、素。(構成)分子。(科学)元素、(数)(集合の)要素、元素、素。(行列の)要素、成分。(図形を火ｔが千都来る)要素。(文法の)要素
• (電子)素子、(光学)素子

関

basal、bases、basic、basis、component、composition、constituent、elementary、factor、fundamentals、ingredient、moiety

　 　 　 　 　

「response」

　　[★]

• n.

• 返答、応答
• 反応、感応、反響。(刺激に対する)反応