エルカトニン
- 関
- avicatonin
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/06 15:17:32」(JST)
[Wiki en表示]
|
This article does not cite any sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (March 2015) (Learn how and when to remove this template message) |
Elcatonin
|
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Identifiers |
CAS Number |
60731-46-6 |
ATC code |
H05BA04 (WHO) |
PubChem |
CID 16129700 |
UNII |
W0CMS474JK Y |
Chemical data |
Formula |
C148H244N42O47 |
Molar mass |
3363.78 g/mol |
(verify) |
Elcatonin is a calcitonin derivative used as an anti-parathyroid agent.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Calcium homeostasis (H05)
|
|
Parathyroid hormone analogues |
|
|
Anti-parathyroid hormone agents |
Calcitonin derivatives
|
|
|
Calcimimetics
|
|
|
Vitamin D analogues
|
- Doxercalciferol
- Paricalcitol
- Cholecalciferol
- Ergocalciferol
- Calcitriol
|
|
|
English Journal
- Elcatonin prevents bone loss caused by skeletal unloading by inhibiting preosteoclast fusion through the unloading-induced high expression of calcitonin receptors in bone marrow cells.
- Tsukamoto M1, Menuki K2, Murai T3, Hatakeyama A4, Takada S5, Furukawa K6, Sakai A7.
- Bone.Bone.2016 Feb 3;85:70-80. doi: 10.1016/j.bone.2016.01.025. [Epub ahead of print]
- This study aimed to clarify whether elcatonin (EL) has a preventive action on bone dynamics in skeletal unloading. Seven-week-old male C57BL/6J mice with either ground control (GC) or tail suspension (TS) were administered EL 20U/kg or a vehicle (veh) three times per week and assigned to one of the
- PMID 26851124
- Elcatonin attenuates disuse osteoporosis after fracture fixation of tubular bone in rats.
- Ji Z1, Shi C2, Huang S3, Dang X4, Wang K5, Lan B6.
- Journal of orthopaedic surgery and research.J Orthop Surg Res.2015 Jul 3;10:103. doi: 10.1186/s13018-015-0246-0.
- BACKGROUND: Elcatonin (ECT) is used to prevent and treat osteoporosis. However, little is known about its effect on the disuse osteoporosis (DOP). The aim of this study is to evaluate the effect of ECT on DOP caused by fracture fixation.METHODS: Forty-five male Sprague-Dawley (SD) rats, aged 6 weeks
- PMID 26138716
- Additive effect of elcatonin to risedronate for chronic back pain and quality of life in postmenopausal women with osteoporosis: a randomized controlled trial.
- Hongo M1, Miyakoshi N, Kasukawa Y, Ishikawa Y, Shimada Y.
- Journal of bone and mineral metabolism.J Bone Miner Metab.2015 Jul;33(4):432-9. doi: 10.1007/s00774-014-0603-9. Epub 2014 Aug 15.
- Calcitonin has been reported to reduce acute and chronic back pain in osteoporotic patients. The additive effect of calcitonin with a bisphosphonate on chronic back pain remains unclear. The purpose of this study was to evaluate the effect of combining elcatonin (eel calcitonin) with risedronate for
- PMID 25123562
Japanese Journal
- Comparison of the Effects of Single Doses of Elcatonin and Pregabalin on Oxaliplatin-Induced Cold and Mechanical Allodynia in Rats
- Aoki Manahito,Kurauchi Yuki,Mori Asami [他]
- Biological & pharmaceutical bulletin 37(2), 322-326, 2014-02
- NAID 40019957195
- Salmon Calcitonin Reduces Oxaliplatin-Induced Cold and Mechanical Allodynia in Rats
- Aoki Manahito,Mori Asami,Nakahara Tsutomu [他],Sakamoto Kenji,Ishii Kunio
- Biological and Pharmaceutical Bulletin 36(2), 326-329, 2013
- … Recently, we reported that elcatonin, a synthetic analog of eel calcitonin, attenuated the oxaliplatin- and paclitaxel-induced cold and mechanical allodynia in rats. …
- NAID 130003361374
- ヒアルロン酸とエルカトニンの付加的効果 : 軟骨下病変を伴う変形性膝関節症の治療
- 石橋 直大,廣瀬 友彦
- 中部日本整形外科災害外科学会雑誌. 中部日本整形外科災害外科学会抄録 55(4), 689-695, 2012-07-01
- NAID 10031015860
Related Links
- Elcatonin is a medicine available in a number of countries worldwide. A list of US medications equivalent to Elcatonin is available on the Drugs.com website. ... Drugs.com provides accurate and independent information on more than ...
- 「Elcatonin フナコシ株式会社 ITSI-Biosciences, LLC」の製品詳細情報ページです。バイオ百科では、その他の関連製品も簡単に検索することができます。 ... 包装単位 希望販売価格(円) 在庫 備考 100mg ご照会下さい 無 中止製品 0 ...
Related Pictures
★リンクテーブル★
[★]
- 英
- elcatonin
- 商
- アデビロック、エカテニン、エカルトニン、エスカトニール、エリンダシン、エルカ、エルシトニン、エルベスタール、オステトニン、ポセビン、ラスカルトン
- 関
- アビカトニン、カルシトニン
[★]
アビカトニン
- 関
- elcatonin