WordNet
- reckoned in a direction opposite to that regarded as positive; "negative interest rates"
- a piece of photographic film showing an image with light and shade or colors reversed
- a reply of denial; "he answered in the negative"
- not indicating the presence of microorganisms or disease or a specific condition; "the HIV test was negative" (同)disconfirming
- having a negative charge; "electrons are negative" (同)electronegative, negatively charged
- characterized by or displaying negation or denial or opposition or resistance; having no positive features; "a negative outlook on life"; "a colorless negative personality"; "a negative evaluation"; "a negative reaction to an advertising campaign"
- expressing or consisting of a negation or refusal or denial
- having the quality of something harmful or unpleasant; "ran a negative campaign"; "delinquents retarded by their negative outlook on life"
- less than zero; "a negative number"
- exercising influence or control; "television plays a dominant role in molding public opinion"; "the dominant partner in the marriage"
- (music) the fifth note of the diatonic scale
- (of genes) producing the same phenotype whether its allele is identical or dissimilar
- (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism (同)genetic mutation, chromosomal_mutation
- a change or alteration in form or qualities
PrepTutorEJDIC
- 『否定の』,反対の / 『消極的な』,控えめの / 陰電気の;(数値が)負の,マイナスの(minus);(写真が)陰画の,ネガの;(医学検査結果が)陰性の / 『否定』,拒否,「いやだ」と言うこと / 否定語[句] / 《the~》(特に討論会の)反対者側,反対派 / (電気分解に用いる)陰極板 / (数値の)負数 / (写真の)陰画,ネガ / 《しばしば受動態に用いて》…‘に'反対投票をする / =negate
- 『支配的な』,最も有力な / (位置が)群を抜いて高い,そびえ立つ / (手・目など左右のいずれかが)力のある / (遺伝で)優性の / (音階で)第5度音の,属音の / (遺伝の)優性形質 / 第5度音,属音
- 変化,俸転 / (生物の)突然変異;その変種
UpToDate Contents
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- 1. 常染色体優性多発性嚢胞腎の診断およびスクリーニング diagnosis of and screening for autosomal dominant polycystic kidney disease
- 2. グラム陰性桿菌性髄膜炎：疫学、臨床的特徴、および診断 gram negative bacillary meningitis epidemiology clinical features and diagnosis
- 3. 常染色体優性間質性腎臓病（髄質嚢胞性腎疾患） autosomal dominant interstitial kidney disease medullary cystic kidney disease
- 4. 家族性筋萎縮性側索硬化症 familial amyotrophic lateral sclerosis
- 5. 傍神経節腫：疫学、臨床症状、診断、および組織学的検査 paragangliomas epidemiology clinical presentation diagnosis and histology
English Journal
- Dysregulation of clathrin promotes thyroid cell growth and contributes to multinodular goiter pathogenesis.
- Lau ST1, Zhou T1, Liu JA1, Fung EY2, Che CM2, Lang BH1, Ngan ES3.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Aug;1852(8):1676-86. doi: 10.1016/j.bbadis.2015.05.005. Epub 2015 May 13.
- A germline mutation (A339V) in thyroid transcription factor-1 (TITF1/NKX2.1) was shown to be associated with multinodular goiter (MNG) and papillary thyroid carcinoma (PTC) pathogenesis. The overexpression of A339V TTF1 significantly promoted hormone-independent growth of the normal thyroid cells, r
- PMID 25981745
- Tryptophan to Glycine mutation in the position 116 leads to protein aggregation and decreases the stability of the LITAF protein.
- Kumar CV1, Swetha RG, Ramaiah S, Anbarasu A.
- Journal of biomolecular structure & dynamics.J Biomol Struct Dyn.2015 Aug;33(8):1695-709. doi: 10.1080/07391102.2014.968211. Epub 2014 Oct 13.
- Mutations in the gene-encoding vesicle lipopolysaccharide-induced tumor necrosis factor (LITAF) protein cause Charcot-Marie-Tooth type 1C (CMT1C) disease, a neurological disorder. The LITAF gene is mapped to chromosome number 16 and can be found at cytogenetic location 16p13 of the chromosome. CMT1C
- PMID 25245565
- GABARAP is a determinant of apoptosis in growth-arrested chicken embryo fibroblasts.
- Maynard S1, Ghosh R, Wu Y, Yan S, Miyake T, Gagliardi M, Rethoret K, Bédard PA.
- Journal of cellular physiology.J Cell Physiol.2015 Jul;230(7):1475-88. doi: 10.1002/jcp.24889.
- Nutrient depletion triggers a series of adaptive processes as part of the unfolded protein response or UPR. These processes reduce stress to the endoplasmic reticulum by enhancing its protein folding capacity or ability to promote the degradation of dysfunctional proteins. Failure to restore ER home
- PMID 25514832
Japanese Journal
- 先天性心疾患における不死化B細胞株由来induced pluripotent stem（iPS）細胞の樹立
- 日本小児循環器学会雑誌 31(6), 313-319, 2015
- NAID 130005116621
- A Heterozygous Missense Mutation in Adolescent-Onset Very Long-Chain Acyl-CoA Dehydrogenase Deficiency with Exercise-Induced Rhabdomyolysis
- The Tohoku Journal of Experimental Medicine 235(4), 305-310, 2015
- NAID 130005061503
- Fertility preservation in a family with a novel <i>NR5A1</i> mutation
- Endocrine Journal 62(3), 289-295, 2015
- NAID 130005060861
Related Links
- Information about Dominant negative mutation in Free online English dictionary. What is Dominant negative mutation? Meaning of Dominant negative mutation medical term. What does Dominant negative mutation mean? forum ...
- Dominant negative mutation Definition(s) A mutation whose gene product adversely affects the normal, wild-type gene product within the same cell, usually by dimerizing (combining) with it. In cases of polymeric molecules, such as ...
Related Pictures
★リンクテーブル★
| リンク元 | 「ドミナントネガティブ変異」「ドミナントネガティブ型変異」 |
| 関連記事 | 「dominant」「negative」 |
「ドミナントネガティブ変異」
「ドミナントネガティブ型変異」
「dominant」
- adj.
- 優性の、優位な、顕性の、優占の、支配的な、ドミナントな
- 関
- dominance、dominantly、manifest、overt、predominance、predominant、predominantly、predominately、prevailing、superior、superiorly
「negative」
- adj.
- 陰性の、負の、ネガティブな、否定的な