びまん性呼吸細気管支炎
WordNet
- spread out; not concentrated in one place; "a large diffuse organization"
- move outward; "The soldiers fanned out" (同)spread, spread out, fan out
- lacking conciseness; "a diffuse historical novel"
- pertaining to respiration; "respiratory assistance"
- a breathing device for administering long-term artificial respiration (同)inhalator
- (of light rays) subjected to scattering by reflection from a rough surface or transmission through a translucent material; "diffused light"
- inflammation of the membranes lining the bronchioles
PrepTutorEJDIC
- 〈光・熱・液体など〉‘を'散らす,放散する,拡散させる / 〈学問・知識など〉‘を'広める,普及させる / 散る,放散する,拡散する / 広まる,普及する / 広く散った,広がった / 〈文体などが〉締まりのない,散漫な
- 呼吸の,呼吸作用の,呼吸のための
- 《米》人工呼吸装置 / (一般に)マスク;防毒マスク
UpToDate Contents
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- 1. 呼吸細気管支炎関連間質性肺疾患 respiratory bronchiolitis associated interstitial lung disease
- 2. 特発性間質性肺炎:臨床症状および病理 idiopathic interstitial pneumonias clinical manifestations and pathology
- 3. 成人における細気管支炎 bronchiolitis in adults
- 4. 間質性肺疾患における肺生検結果の解釈 interpretation of lung biopsy results in interstitial lung disease
- 5. 肺の高分解能CT high resolution computed tomography of the lungs
English Journal
- Lung Transplant Outcomes in Systemic Sclerosis with Significant Esophageal Dysfunction. A Comprehensive Single-Center Experience.
- Miele CH1, Schwab K1, Saggar R2, Duffy E1,3, Elashoff D1,3, Tseng CH1,3, Weigt S1,4,5, Charan D1, Abtin F6, Johannes J1,4,5, Derhovanessian A1,4,5, Conklin J7, Ghassemi K7, Khanna D8, Siddiqui O9, Ardehali A5, Hunter C5, Kwon M5, Biniwale R5, Lo M1, Volkmann E10, Torres Barba D1, Belperio JA1,4,5, Sayah D4,5, Mahrer T11, Furst DE10, Kafaja S10, Clements P8, Shino M4,5, Gregson A1, Kubak B1, Lynch JP 3rd1,4, Ross D1,4,5, Saggar R1,4,5.
- Annals of the American Thoracic Society.Ann Am Thorac Soc.2016 Jun;13(6):793-802. doi: 10.1513/AnnalsATS.201512-806OC.
- RATIONALE: Consideration of lung transplantation in patients with systemic sclerosis (SSc) remains guarded, often due to the concern for esophageal dysfunction and the associated potential for allograft injury and suboptimal post-lung transplantation outcomes.OBJECTIVES: The purpose of this study wa
- PMID 27078625
- Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia syndrome.
- Rossi G1, Cavazza A2, Spagnolo P3, Sverzellati N4, Longo L5, Jukna A6, Montanari G7, Carbonelli C8, Vincenzi G9, Bogina G10, Franco R11, Tiseo M12, Cottin V13, Colby TV14.
- The European respiratory journal.Eur Respir J.2016 Jun;47(6):1829-41. doi: 10.1183/13993003.01954-2015. Epub 2016 Apr 13.
- The term diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) may be used to describe a clinico-pathological syndrome, as well as an incidental finding on histological examination, although there are obvious differences between these two scenarios. According to the World Health Org
- PMID 27076588
- Pulmonary manifestations of Sjögren's syndrome.
- Flament T1, Bigot A2, Chaigne B2, Henique H3, Diot E2, Marchand-Adam S4.
- European respiratory review : an official journal of the European Respiratory Society.Eur Respir Rev.2016 Jun;25(140):110-23. doi: 10.1183/16000617.0011-2016.
- In 9-20% of cases, Sjögren's syndrome is associated with various respiratory symptoms. The most typical manifestations are chronic interstitial lung disease (ILD) and tracheobronchial disease. The most common manifestation of ILD is nonspecific interstitial pneumonia in its fibrosing variant. Other
- PMID 27246587
Japanese Journal
- 若年性脳腫瘍が原因と考えられた慢性嚥下性肺炎の1例
- 宮川 倫子,望月 吉郎,中原 保治,河村 哲治,佐々木 信,塚本 宏壮,田畑 寿子,岡田 秀明,小橋 陽一郎
- 日本呼吸器学会雑誌 = The journal of the Japanese Respiratory
- NAID 10024823805
- High Prevalence of Diffuse Parenchymal Lung Diseases among Turkish Tinners
- DIKENSOY Oner,KERVANCIOGLU Resat,EGE Ibrahim,UYSAL Nevin,ELBEK Osman,OZKUR Ayhan
- Journal of occupational health 50(2), 208-211, 2008-03
- … Of these 11 subjects, HRCT findings were consistent with respiratory bronchiolitis interstitial lung disease in nine, usual interstitial pneumonia pattern in one, and non-specific interstitial pneumonia in one. …
- NAID 110006680541
- Non-Infectious Bronchiolitis as an Early Pulmonary Complication of Hematopoietic Stem Cell Transplantation
- Kage Hidenori,Kohyama Tadashi,Kitagawa Hiroshi,Takai Daiya,Kanda Yoshinobu,Ohishi Nobuya,Nagase Takahide
- Internal Medicine 47(1), 61-64, 2008
- … Among them, non-infectious bronchiolitis is considered a late complication in the form of bronchiolitis obliterans. … We report a patient who developed non-infectious bronchiolitis within four weeks after undergoing HSCT for biphenotypic leukemia. … Chest CT revealed centrilobular nodules that were reminiscent of diffuse panbronchiolitis, and lymphocytic bronchiolitis was confirmed by biopsy. …
- NAID 130000078704
Related Links
- Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a type of idiopathic interstitial pneumonia (IIP) that has pathologic features of respiratory bronchiolitis (RB). The other IIPs include idiopathic pulmonary fibrosis ...
- ... et al. Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. Am Rev Respir Dis 1992; 146:196. Oda H, Kadota J, Kohno S, Hara K. Erythromycin ...
★リンクテーブル★
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- 英
- diffuse panbronchiolitis, DPB
- 同
- びまん性呼吸細気管支炎 diffuse respiratory bronchiolitis
- 関
- 細気管支炎
概念
- 呼吸細気管支領域の慢性炎症性病変が肺内にびまん性に分布し、炎症反応が細気管支壁の全層に及ぶ原因不明の疾患。慢性の咳嗽・喀痰が認められ、慢性気道感染と拘束性の肺機能障害が認められる。副鼻腔炎の合併が認められることがあり、副鼻腔気管支症候群としてまとめられることがある。
- 胸部単純X線写真上、下肺野優位に両肺野びまん性小葉中心性粒状陰影が認められる(小葉中心性病変)。
- これまでは予後不良であったが、エリスロマイシン少量投与で著明な治療効果が認められる。
疫学
病態
病変の首座は終末細気管支及び終末細気管支周囲炎(出典不明)
- 呼吸細気管支を中心とした細気管支およびその周囲炎 (YN.I-76)
- 泡沫細胞の集簇を伴ったリンパ球、形質細胞など円形細胞浸潤
症状
身体所見
検査
- 胸部単純X線写真:気管支拡張がみられる
- 胸部単純CT:下肺野優位に両肺野びまん性小葉中心性粒状陰影 ← 小葉中心性病変 (cf.小葉)
- 肺機能検査:一秒率低下、残気量増加、肺拡散能不変。
合併症
治療
- 予後は不良であったが、エリスロマイシンの少量長期投与により予後が改善 30年生存率38-63%
参考
- 1. [charged] Diffuse panbronchiolitis - uptodate [1]
国試
[★]
- 関
- diffusely、diffusion、diffusional、diffusive、disseminated、pervasive、spread、widespread
[★]
- 関
- breath、breathe、breathing、respiration、respiratory mechanics、respiratory organ、respiratory tract