- 関
- CYP2D6
WordNet
- the 16th letter of the Roman alphabet (同)p
- (biochemistry) a class of hemoprotein whose principal biological function is electron transfer (especially in cellular respiration)
- a river in western Thailand; a major tributary of the Chao Phraya (同)Ping River
PrepTutorEJDIC
- parking
- phosphorusの化学記号
- palladiumの化学記号
UpToDate Contents
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- 1. 薬理ゲノム学の概要 overview of pharmacogenomics
- 2. 基底細胞癌の疫学、発症機序、臨床的特徴 epidemiology pathogenesis and clinical features of basal cell carcinoma
- 3. 薬と肝臓：代謝および肝障害の機序 drugs and the liver metabolism and mechanisms of injury
- 4. 選択的エストロゲン受容体モジュレーター・受容体ダウンレギュレーターの作用機序 mechanisms of action of selective estrogen receptor modulators and down regulators
- 5. スタチン：作用、副作用、および投与 statins actions side effects and administration
English Journal
- New FDA black box warning for codeine: how will this affect dentists?
- Weaver JM.
- Anesthesia progress.Anesth Prog.2013 Summer;60(2):35-6. doi: 10.2344/0003-3006-60.2.35.
- PMID 23763556
- Double site saturation mutagenesis of the human cytochrome P450 2D6 results in regioselective steroid hydroxylation.
- Geier M, Braun A, Fladischer P, Stepniak P, Rudroff F, Hametner C, Mihovilovic MD, Glieder A.SourceInstitute of Molecular Biotechnology, Graz University of Technology, Graz, Austria.
- The FEBS journal.FEBS J.2013 Jul;280(13):3094-108. doi: 10.1111/febs.12270. Epub 2013 May 3.
- The human cytochrome P450 2D6 (CYP2D6) is one of the major human drug metabolizing enzymes and acts preferably on substrates containing a basic nitrogen atom. Testosterone - just as other steroids - is an atypical substrate and only poorly metabolized by CYP2D6. The present study intended to investi
- PMID 23552177
- First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.
- Zhou K, Khokhar JY, Zhao B, Tyndale RF.SourceDepartments of Pharmacology & Toxicology and Psychiatry, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.
- Biochemical pharmacology.Biochem Pharmacol.2013 Jun 15;85(12):1848-55. doi: 10.1016/j.bcp.2013.04.014. Epub 2013 Apr 23.
- The response to centrally acting drugs is highly variable between individuals and does not always correlate with plasma drug levels. Drug-metabolizing CYP enzymes in the brain may contribute to this variability by affecting local drug and metabolite concentrations. CYP2D metabolizes codeine to the a
- PMID 23623752
Japanese Journal
- 薬物の効果や体内動態の個人差と遺伝子多型
- 家入 一郎
- Organ Biology 21(2), 247-253, 2014
- … Genetic polymorphism in drug metabolizing enzymes and drug transporters has been focused on currently, especially for cytochrome P-450s (CYPs, such as CYP2C9, CYP2C19, and CYP2D6), and organic anion transporting polypeptides 1B1(OATP1B1)and pglycoprotein, respectively, are available in various clinical situations. …
- NAID 130004715813
- 抗cytochrome P 450 2D6抗体(CYP2D6抗体) (広範囲 血液・尿化学検査 免疫学的検査(第7版・3)その数値をどう読むか) -- (免疫学的検査 自己抗体)
- 網野 信行,藤原 真子
- 日本臨床 68(-), 592-595, 2010-06
- NAID 40017181845
- Effect of Equisetum arvense L. Extract on Cytochrome P-450 Activities in Human Liver Microsomes and Prediction of Interaction with Blood Drug Metabolism
- 安達 弥永,安保 智子,藤島 美紀,渡邊 治夫
- 生活衛生 54(2), 137-145, 2010
- … extract) on the metabolic activities of drugs with specific activity on cytochrome P-450 isozymes (1A2, 2C9, 2C19, 2D6, 2E1, and 3A4) were investigated using human liver microsomes. … Although CYP2D6 and CYP2E retained 66.7% and 73.4% of activity at <I>Equisetum</I> …
- NAID 130004448996
Related Links
- Review of cytochrome P450 2D6. Inducers, inhibitors, substrates. CYP2D6 ... CYP2D6 INDUCERS INTERACTION If Drug A is metabolized by CYP2D6, and it is taken with Drug B, a CYP2D6 inducer, then blood levels of Drug A may ...
- Cytochrome P(450)IID6's activity may play a role in the development of Type 1 diabetes mellitus. The observed frequency of the CYP2D6 alleles tested was unique for the Mexican Mestizo sample analyzed We have examined ...
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| リンク元 | 「チトクロムP450酵素CYP2D6」 |
| 関連記事 | 「CYP2D6」「P」「p」「Pd」「cytochrome P」 |
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