出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/07/27 17:20:49」(JST)
Cystic duct | |
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1: Right lobe of liver
2: Left lobe of liver |
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Latin | ductus cysticus |
Gray's | p.1198 |
Artery | cystic artery |
The cystic duct is the short duct that joins the gallbladder to the common bile duct. It usually lies next to the cystic artery. It is of variable length. It contains 'spiral valves of Heister,' which do not provide much resistance to the flow of bile.
Bile can flow in both directions between the gallbladder and the common hepatic duct and the (common) bile duct.
In this way, bile is stored in the gallbladder in between meal times. The hormone cholecystokinin, when stimulated by a fatty meal, promotes bile secretion by increased production of hepatic bile, contraction of the gall bladder, and relaxation of the Sphincter of Oddi.
Gallstones can enter and obstruct the cystic duct, preventing the flow of bile. The increased pressure in the gallbladder leads to swelling and pain. This pain, known as biliary colic, is sometimes referred to as a gallbladder "attack" because of its sudden onset.
During a cholecystectomy, the cystic duct is clipped two or three times and a cut is made between the clips, freeing the gallbladder to be taken out.
This is a leak from the cystic duct stump in post cholecystectomy patients. It was rarely reported in open cholecystectomy patients. Since the advent of laparoscopic cholecystectomy the incidence of CDSL has increased with one study doing it to occur in 0.1 to 0.2% of patientss[1] Cystic duct stump leak is the commonest cause of bile leak and technical morbidity according to one study. [2]The cause may be not related the presence of emergency laparoscopic cholecystecomies as one study showed that only 46.6% of CDSL occurred with acute cholecystitis.[3]
Theories of the CDSL include:
1. Cystic duct displacement:
2. Necrosis of cystic duct stump proximal to clip: This would occur proximal to the applied clip. Necrosis may be secondary to electrocautery creating a phenomenon called "clip-coupling" in which excessive electrocautery near the clips, conducted via the metal in the clips, causes necrosis of the proximal cystic duct[6]
3. Ischemic necrosis secondary to devascularization: One study showed that blood flow can be disrupted from dissecting. One study showed a pseudoaneurysm of the right hepatic artery causing vascular disrupting blood supply to the cystic duct. A solution is dividing the cystic artery distally. [7]
4. Increased biliary pressure: This can be due to a retained common bile duct stone creating pressure in the biliary tree. This may be the most rare causes of CDSL. [8]
CDSL presents 3 to 4 days after operation with right upper quandrant pain, followed by nausea, vomiting, and fever. High WBC is described in 68% of patient. Liver function tests can be highly variable.[9]
Initial test is ultrasonography to screen out biloma, ascites, or retained stones. Computed tomgraphy has a high sensitivity approaching 100% for detecting leaks. The most successful imaging is from ERCP. ERCP has the additional value of allowing for treatment which often consists of sphincterotomy with common bile duct stenting.
Digestive system diagram showing the cystic duct
The gall-bladder and bile ducts laid open.
The portal vein and its tributaries.
Cystic duct.Visceral surface of liver.
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リンク元 | 「impact」「胆嚢管」 |
拡張検索 | 「cystic duct stump syndrome」 |
関連記事 | 「duct」「cystic」 |
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