WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
the 4th letter of the Roman alphabet (同)d
informal term for information; "give me the gen on your new line of computers"

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遺伝子
deuteriumの化学記号
(おもに人称代名詞・固有名詞(人名),thereの後で)had, wouldの短縮形 / (疑問文でwhere,what,whenの後で)didの短縮形;Where'd he go?=Where did he go?

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1. 黒色腫（メラノーマ）に対する遺伝的感受性 inherited susceptibility to melanoma
2. マントル細胞リンパ腫の病理学 pathobiology of mantle cell lymphoma
3. 多発性内分泌腫瘍1型：定義および遺伝学 multiple endocrine neoplasia type 1 definition and genetics
4. 前立腺癌の分子生物学 molecular biology of prostate cancer
5. 急性骨髄性白血病の分子遺伝学 molecular genetics of acute myeloid leukemia

Cellular conservation of endangered midget buffalo (Lowland Anoa, Bubalus quarlesi) by establishment of primary cultured cell, and its immortalization with expression of cell cycle regulators.

Fukuda T1,2, Iino Y3, Eitsuka T4, Onuma M5,6, Katayama M5,6, Murata K7, Inoue-Murayama M5,8, Hara K9, Isogai E3, Kiyono T10.
Cytotechnology.Cytotechnology.2016 Oct;68(5):1937-47. doi: 10.1007/s10616-016-0004-0. Epub 2016 Jul 23.
Lowland Anoa has become endangered due to hunting and human activity. Protection and breeding of endangered species in a controlled environment is the best way of conservation. However, it is not possible to adopt this approach for all endangered species because of the cost involved and the ever-inc
PMID 27449922

Functional characterization of the ribosome biogenesis factors PES, BOP1, and WDR12 (PeBoW), and mechanisms of defective cell growth and proliferation caused by PeBoW deficiency in Arabidopsis.

Ahn CS1, Cho HK1, Lee DH1, Sim HJ2, Kim SG2, Pai HS3.
Journal of experimental botany.J Exp Bot.2016 Sep;67(17):5217-32. doi: 10.1093/jxb/erw288. Epub 2016 Jul 20.
The nucleolar protein pescadillo (PES) controls biogenesis of the 60S ribosomal subunit through functional interactions with Block of Proliferation 1 (BOP1) and WD Repeat Domain 12 (WDR12) in plants. In this study, we determined protein characteristics and in planta functions of BOP1 and WDR12, and
PMID 27440937

Conley SJ1, Bosco EE1, Tice DA1, Hollingsworth RE1, Herbst R1, Xiao Z1.
Oncogene.Oncogene.2016 Aug 11;35(32):4225-34. doi: 10.1038/onc.2015.487. Epub 2016 Jan 4.
Mucin-like 1 (MUCL1) was first identified as a breast-specific gene over a decade ago. Based on its highly restricted mRNA expression in breast tissue and continued expression during breast tumorigenesis and progression, MUCL1 is an attractive tumor-associated antigen and a potential therapeutic tar
PMID 26725324

The GANT61, a GLI Inhibitor, Induces Caspase-Independent Apoptosis of SK-N-LO Cells

Matsumoto Takahiro,Tabata Keiichi,Suzuki Takashi
Biological and Pharmaceutical Bulletin 37(4), 633-641, 2014
… The most sensitive cell line was SK-N-LO, which expresses the EWS-FLI1 fusion gene. … Significant decrease of the protein levels of GLI2, survivin, cyclin A and claspin, and significant increase of p21 expression was also observed in the cells treated with GANT61. …
NAID 130003390968

蛭川英典
川崎医学会誌 40(1), 13-26, 2014
… みた.遺伝子解析では,Insulin遺伝子発現量はALO群と併用群で増加し,PIO群ではインスリン抵抗性改善を反映し減少傾向を示した.GLUT2遺伝子発現は全実薬群で増加傾向を認め,併用群でその傾向は強かった.PDX-1,MafA,Cyclin DおよびBcl-2遺伝子はALO群,PIO群で増加傾向を示し,併用群で顕著であった.膵β細胞量および機能維持に必須であるIRS-2遺伝子の発現量はALO群で増加傾向を示し,併用群で顕著に増幅された.また,GLP-1R遺伝子発現はA …
NAID 110009804572