WordNet
- make complete or perfect; supply what is wanting or form the complement to; "I need some pepper to complement the sweet touch in the soup"
- a complete number or quantity; "a full complement"
- one of a series of enzymes in the blood serum that are part of the immune response
- something added to complete or embellish or make perfect; "a fine wine is a perfect complement to the dinner"; "wild rice was served as an accompaniment to the main dish" (同)accompaniment
- number needed to make up a whole force; "a full complement of workers" (同)full complement
- a word or phrase used to complete a grammatical construction
- either of two parts that mutually complete each other
- a trodden path (同)footpath
PrepTutorEJDIC
- (あるものを完全にするため)(…を)補う物(事)《+『of』+『名』》 / 補語(文法で文の成分の一つ) / (必要な)全数,全量;(船の)定員 / …を補足する,補う
- 道,小道(path)
UpToDate Contents
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- 1. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
- 2. 補体系の後天性疾患 acquired disorders of the complement system
- 3. 補体経路 complement pathways
- 4. Inherited disorders of the complement system
- 5. 補体系の制御因子および受容体 regulators and receptors of the complement system
English Journal
- Properdin in complement activation and tissue injury.
- Lesher AM, Nilsson B, Song WC.SourceDepartment of Pharmacology and Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
- Molecular immunology.Mol Immunol.2013 Dec 15;56(3):191-8. doi: 10.1016/j.molimm.2013.06.002. Epub 2013 Jun 29.
- The plasma protein properdin is the only known positive regulator of complement activation. Although regarded as an initiator of the alternative pathway of complement activation at the time of its discovery more than a half century ago, the role and mechanism of action of properdin in the complement
- PMID 23816404
- Complement therapy in atypical haemolytic uraemic syndrome (aHUS).
- Wong EK, Goodship TH, Kavanagh D.SourceThe Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
- Molecular immunology.Mol Immunol.2013 Dec 15;56(3):199-212. doi: 10.1016/j.molimm.2013.05.224. Epub 2013 Jun 28.
- Central to the pathogenesis of atypical haemolytic uraemic syndrome (aHUS) is over-activation of the alternative pathway of complement. Inherited defects in complement genes and autoantibodies against complement regulatory proteins have been described. The use of plasma exchange to replace non-funct
- PMID 23810412
- Toward a structure-based comprehension of the lectin pathway of complement.
- Kjaer TR, Thiel S, Andersen GR.SourceDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
- Molecular immunology.Mol Immunol.2013 Dec 15;56(3):222-31. doi: 10.1016/j.molimm.2013.05.220. Epub 2013 Jun 27.
- To initiate the lectin pathway of complement pattern recognition molecules bind to surface-linked carbohydrates or acetyl groups on pathogens or damaged self-tissue. This leads to activation of the serine proteases MASP-1 and MASP-2 resulting in deposition of C4 on the activator and assembly of the
- PMID 23810291
Japanese Journal
- 血清レクチンとメタロプロテアーゼとの相互作用のもつ生理的・病理的意義
- 平野 真
- 成蹊大学理工学研究報告 = The journal of the Faculty of Science and Technology, Seikei University 49(2), 33-44, 2012-12-01
- … On the other hand, focusing on the pathogenic role of the interaction of MBP with meprins, we clarified that, in an acute renal failure caused by ischemia/reperfusion injury, the binding of MBP with meprins triggers the complement activation on the renal proximal tubules through the lectin pathway. …
- NAID 120005271065
- Atypical HUS
- 吉田 瑶子,松本 雅則,早川 正樹,藤村 吉博
- 日本アフェレシス学会雑誌 31(1), 27-32, 2012-02-29
- … Recent studies have revealed that aHUS is a disease of complement dysregulation with 50-60% of cases involving the complement regulatory genes, factor H (CFH), membrane cofactor protein (MCP;CD46) and factor I (FI) and so on. … Therefore, it is necessary to establish an appropriate diagnostic pathway focusing on the complement system for choosing the most favorable therapeutic approach in Japan. …
- NAID 110009327450
- 溶血性尿毒症症候群(Hemolytic Uremic Syndrome:HUS)(<特集>血小板減少症とアフェレシス)
- 芦田 明,玉井 浩
- 日本アフェレシス学会雑誌 31(1), 20-26, 2012-02-29
- … Recently, it has been clarified that Stx activates a complement in human serum through an alternative pathway by binding to the cell-binding domains of complement factor H and inhibiting its regulatory function. … In addition, newer treatments for typical HUS are currently being examined, including Shiga toxin-neutralizing antibodies, multibranched Stx receptor analogs, and therapies targetting the terminal complement cascade. …
- NAID 110009327449
Related Links
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- pathway /path·way/ (path´wa) 1. a course usually followed. 2. the nerve structures through which an impulse passes between groups of nerve cells or between the central nervous system and an organ or muscle. 3. metabolic p.. ...
Related Pictures
★リンクテーブル★
| リンク元 | 「補体活性化経路」 |
| 拡張検索 | 「alternative complement pathway」「classical complement pathway」 |
| 関連記事 | 「complement」「pathway」 |
「補体活性化経路」
- 英
- complement pathway
- 同
- complement cascade
「alternative complement pathway」
「classical complement pathway」
「complement」
- n.
- 補って完全にする物、補完物。(免疫)補体
- (必要な)全数、善良
- vt.
- 補って完全にする。補完する。～の補足となる。
「pathway」
- 関
- route