同: CINCA

WordNet

an impairment of health or a condition of abnormal functioning
being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate
of or relating to infants or infancy; "infantile paralysis"
being or befitting or characteristic of an infant; "infantile games"
caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological

PrepTutorEJDIC

《語・句・節を対等に結んで》…『と』…,…や…,および / 《数詞を結合して》…『足す』…,…に加えて / …『しかも』…,…して,同時に… / 《時間的に》『そして』,それから,すると(and then) / 《当然の帰結として》…『ので』,…だから(and so) / 《おもに話》《命令文などの後で》『そうすれば』,そうしたら / 《追加・強調して》それに,しかも / 《対照的な内容を導いて》ところが,しかし(but) / 《譲歩的に》それなのに,それでいながら / 《A and Bで一体の関係を表して》《単数扱い》 / 《同一語を反復して多数・継続などを表して》 / 《同一の複数名詞を結合して変化・種類などを表して》 / 《話》《「形容詞+and+形容詞」の形で前の形容詞が後に副詞的に働く》 / 《話》《「動詞come, goなど+and+動詞」の形でandとその後の動詞が不定詞の働きをして》 / 《「動詞+and+動詞」の形で後の動詞が現在分詞の意を表して》 / 《話》《文頭において前の質問・意見などに同意を示して》そうとも,そして(Yes!and) / 《話》《文頭に置いて驚き・疑念・非難などを表して》ほんとうに;…なのに
(体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
女性の話術芸人 =diseur
(病気が)長期にわたる,慢性の / 《名詞の前にのみ用いて》常習の,癖になった
《名詞の前にのみ用いて》幼時の / 子供じみた;子供らしい
病気にかかった / 病的な,不健全な(morbid)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. クリオピリン関連周期性発熱症候群および関連疾患 cryopyrin associated periodic syndromes and related disorders
2. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
3. アミロイド疾患の遺伝的要因 genetic factors in the amyloid diseases
4. 続発性（AA）アミロイドーシスの治療 treatment of secondary aa amyloidosis
5. 周期性発熱症候群およびその他の自己炎症性疾患：概要 periodic fever syndromes and other autoinflammatory diseases an overview

English Journal

Diagnosis of cryopyrin-associated periodic syndrome: challenges, recommendations and emerging concepts.

Sarrabay G1, Grandemange S, Touitou I.
Expert review of clinical immunology.Expert Rev Clin Immunol.2015 May 15:1-9. [Epub ahead of print]
Cryopyrin-associated periodic syndrome are rare autosomal dominantly inherited diseases. They include three overlapping phenotypes: familial cold autoinflammatory syndrome, Muckle-Wells syndrome, and chronic infantile neurological cutaneous articular syndrome/neonatal onset multisystem autoinflammat
PMID 25979514

CINCA syndrome with surgical intervention for valgus deformity and flexion contracture of the knee joint: a case report.

Harada Y, Fukiage K, Nishikomori R, Suzuki S, Futami T.
Modern rheumatology / the Japan Rheumatism Association.Mod Rheumatol.2015 Apr 13:1-15. [Epub ahead of print]
Chronic infantile neurological, cutaneous and articular ( CINCA ) syndrome is a systemic autoinflammatory disease caused by increased production of IL-1 beta. We present a case of CINCA syndrome followed up to skeletal maturity . Joint contracture and valgus deformity of the knee had developed befor
PMID 25867226

[Cryopyrine-associated periodic syndrome: CAPS seen from adulthood].

Koné-Paut I1.
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne.Rev Med Interne.2015 Apr;36(4):277-82. doi: 10.1016/j.revmed.2014.10.006. Epub 2015 Jan 13.
Cryopyrin-associated periodic syndrome is a rare hereditary periodic fever syndrome for which, the genetic mechanism, mutation in the NLRP3 gene, has allowed to gather 3 clinical phenotypes (familial cold urticaria [FCAS], Muckle-Wells syndrome [MWS], and chronic infantile neurological cutaneous an
PMID 25595876