WordNet

any of various organs that synthesize substances needed by the body and release it through ducts or directly into the bloodstream (同)secretory organ, secretor, secreter
of or relating to the heart; "cardiac arrest"
the opening into the stomach and that part of the stomach connected to the esophagus

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(生物体内の)腺(せん)
心臓の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/10/09 06:08:55」(JST)

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The cardiac glands of the stomach secrete primarily mucus. In humans, they are few in number and occur close to the cardiac orifice where the esophagus joins the stomach.

In general, they are more shallow than those in the other parts of the stomach.

They are of two kinds:

(1) simple tubular glands resembling those of the pyloric end of the stomach, but with short ducts.
(2) compound racemose glands resembling the duodenal glands.

The cardiac gland is both innervated by the parasympathetic and sympathetic nerve fibres of the autonomic nervous system.

External links

cardiac+gland at eMedicine Dictionary
Histology at OU 100_04 - "Esophageal-stomach junction"
Histology image: 11103loa - Histology Learning System at Boston University - "Digestive System: Alimentary Canal: esophageal/stomach junction"

This article incorporates text from a public domain edition of Gray's Anatomy.

This human digestive system article is a stub. You can help Wikipedia by expanding it.

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1. 鈍的外傷による心損傷 cardiac injury from blunt trauma
2. 心臓腫瘍 cardiac tumors
3. 成人における心停止後のマネージメント post cardiac arrest management in adults
4. 唾液腺腫瘍：疫学、診断、評価、および病期分類 salivary gland tumors epidemiology diagnosis evaluation and staging
5. 突然の心停止生存者の評価 evaluation of the survivor of sudden cardiac arrest

English Journal

Gastric cancer progression may involve a shift in HLA-E profile from an intact heterodimer to β2-microglobulin-free monomer.

Sasaki T, Ravindranath MH, Terasaki PI, Freitas MC, Kawakita S, Jucaud V.Author information Terasaki Foundation Laboratory, Los Angeles, CA; Department of Surgery, Jikei University School of Medicine, Tokyo, Japan.AbstractPhenotypic expression of human leukocyte antigen (HLA)-E on the surface of tumor lesions includes intact heterodimer [HLA-E heavy chain and β2-microglobulin (β2m)] and β2m-free monomer. Anti-HLA-E monoclonal antibodies (mAbs), MEM-E/02 or 3D12 bind to the peptide sequences in β2m-free HLA-E, which is common and shared with HLA-Ia monomers. A newly developed monospecific anti-HLA-E mAb (TFL-033) recognizes HLA-E-restricted peptide sequences on α1 and α2 helices away from β2-m-site. Tumor progression may involve shedding of β2-m from HLA-E or overexpression of β2m-free monomers. There is a need to identify and distinguish the different phenotypic expression of HLA-E, particularly the intact heterodimer from the β2m-free monomer on the surface of tumor lesions. Because of the unique peptide-binding affinities of the mAbs, it is hypothesized that TFL-033 and MEM-E/02 may distinguish the phenotypic expressions of cell surface HLA-E during stages of tumor progression. Only TFL-033 stained diffusely the cytoplasm of normal mucosa. The incidence and intensity of TFL-033 staining of the cell surface in early stages, poorly or undifferentiated and non-nodal lesions and in diffuse carcinoma is greater than that of MEM-E/02. Whereas MEM-E/02 stained terminal stages, adenocarcinoma and lymph node metastatic lesions intensely, either owing to increased expression of β2m-free HLA-E with tumor progression or owing to expression of HLA-Ia molecules. Our study evaluates the relative diagnostic potential of HLA-E-monospecific TFL-033 and the HLA-Ia-reactive MEM-E/02 for determining the specific distribution and immunodiagnosis of different phenotypic expression HLA-E in tumor lesions, and the structural and functional alterations undergone by HLA-E during tumor progression.
International journal of cancer. Journal international du cancer.Int J Cancer.2014 Apr 1;134(7):1558-70. doi: 10.1002/ijc.28484. Epub 2013 Dec 11.
Phenotypic expression of human leukocyte antigen (HLA)-E on the surface of tumor lesions includes intact heterodimer [HLA-E heavy chain and β2-microglobulin (β2m)] and β2m-free monomer. Anti-HLA-E monoclonal antibodies (mAbs), MEM-E/02 or 3D12 bind to the peptide sequences in β2m-free HLA-E, whi
PMID 24105714

Protective effect of chelerythrine against ethanol-induced gastric ulcer in mice.

Li WF1, Hao DJ2, Fan T3, Huang HM1, Yao H1, Niu XF4.Author information 1School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.2Xi'an Red Cross Hospital, Xi'an 710054, China.3School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China; Xi'an Red Cross Hospital, Xi'an 710054, China.4School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address: niuxf@mail.xjtu.edu.cn.AbstractThe quaternary benzo[c]phenanthridine alkaloid, chelerythrine (CHE), is of great practical and research interest because of its pronounced, widespread physiological effects, primarily antimicrobial and anti-inflammatory, arising from its ability to interact with proteins and DNA. Although CHE was originally shown to possess anti-inflammatory properties, its effects on acute gastric ulcer have not been previously explored. The aim of the present study is to evaluate the protective effect of CHE on ethanol induced gastric ulcer in mice. Administration of CHE at doses of 1, 5 and 10mg/kg bodyweight prior to ethanol ingestion dose-dependently inhibited gastric ulcer. The gastric mucosal lesion was assessed by ulcer area, gastric juice acidity, myeloperoxidase (MPO) activities, macroscopic and histopathological examinations. CHE significantly reduced the gastric ulcer index, myeloperoxidase activities, macroscopic and histological score in a dose-dependent manner. In addition, CHE also significantly inhibited nitric oxide (NO) concentration, pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) level in serum and gastric mucosal in the mice exposed to ethanol induced ulceration in a dose-dependent manner. In addition, immunohistochemical analysis revealed that CHE markedly attenuated the overexpression of nuclear factor-κB in gastric mucosa of mice. It was concluded that CHE represents a potential therapeutic option to reduce the risk of gastric ulceration. In addition, acute toxicity study revealed no abnormal sign to the mice treated with CHE (15mg/kg). These findings suggest that the gastroprotective activity of CHE might contribute in adjusting the inflammatory cytokine by regulating the NF-κB signalling pathway.
Chemico-biological interactions.Chem Biol Interact.2014 Feb 5;208:18-27. doi: 10.1016/j.cbi.2013.11.011. Epub 2013 Dec 1.
The quaternary benzo[c]phenanthridine alkaloid, chelerythrine (CHE), is of great practical and research interest because of its pronounced, widespread physiological effects, primarily antimicrobial and anti-inflammatory, arising from its ability to interact with proteins and DNA. Although CHE was or
PMID 24300194

Japanese Journal

Antipredator Displays and Prey Chemical Preference of an Asian Natricine Snake, Macropisthodon rudis (Squamata: Colubridae)

TAKEUCHI HIROHIKO,MORI AKIRA
Current Herpetology 31(1), 47-53, 2012
… Extensive studies on the nuchal glands of Rhabdophis tigrinus have shown that the glands contain cardiac steroidal toxins known as bufadienolides, which are sequestered from its toad prey and are stored in the nuchal glands as defensive substances. … In addition, several species of snakes with nuchal glands exhibit unique behaviors to enhance the effects of the glands (nuchal gland-related behaviors). …
NAID 130002072891

心疾患がアルベカシンの血中薬物動態に与える影響

石田茂伸,山崎圭一,梅田喜亮,前田佳代,大島利夫,中井由佳
日本化学療法学会雜誌 = Japanese journal of chemotherapy 59(4), 374-378, 2011-07-10
NAID 10029365277

Related Pictures

★リンクテーブル★

リンク元	「噴門腺」「gastric gland」「gastric mucosa」
関連記事	「cardiac」

「噴門腺」

Cardiac glands
	Section of mucous membrane of human stomach, near the cardiac orifice. X 45.; c. Cardiac glands.; d. Their ducts.; cr. Gland similar to the intestinal glands, with goblet cells.; mm. Mucous membrane.; m. Muscularis mucosae.; m’. Muscular tissue within the mucous membrane.
Gray's	p.1166
	Anatomical terminology