WordNet

perform as expected when applied; "The washing machine wont go unless its plugged in"; "Does this old car still run well?"; "This old radio doesnt work anymore" (同)work, operate, go, run
(mathematics) a mathematical relation such that each element of a given set (the domain of the function) is associated with an element of another set (the range of the function) (同)mathematical function, single-valued function, map, mapping
a relation such that one thing is dependent on another; "height is a function of age"; "price is a function of supply and demand"
the actions and activities assigned to or required or expected of a person or group; "the function of a teacher"; "the government must do its part"; "play its role" (同)office, part, role
what something is used for; "the function of an auger is to bore holes"; "ballet is beautiful but what use is it?" (同)purpose, role, use
a formal or official social gathering or ceremony; "it was a black-tie function"
the trace of a point whose direction of motion changes (同)curved shape
a pitch of a baseball that is thrown with spin so that its path curves as it approaches the batter (同)curve ball, breaking ball, bender
a line on a graph representing data
an inferior dog or one of mixed breed (同)mongrel, mutt
a cowardly and despicable person
of or relating to the heart; "cardiac arrest"
having or marked by a curve or smoothly rounded bend; "the curved tusks of a walrus"; "his curved lips suggested a smile but his eyes were hard" (同)curving

PrepTutorEJDIC

(人・物の果たすべき)『働き』,機能,役目;《しばしば複数形で》職務 / (公式の)儀式,《話》大きな催し(集まり),式典 / (数学で)関数 / 〈機械などが〉『機能を果たす』,動く / (…の)役目をする,代用となる《+『as』+『名』》
『曲線』 / 『曲がり』,曲がったもの,湾曲部 / (野球で投球の)『カーブ』 / (…の方へ)『曲がる』,湾曲する《+『to』+『名』》 / …'を'曲げる;'を'湾曲させる
のら犬 / くだらない人間
心臓の

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/03 07:44:43」(JST)

wiki en

A cardiac function curve is a graph showing the relationship between right atrial pressure (x-axis) and cardiac output (y-axis).

Superimposition of the cardiac function curve and venous return curve is used in one hemodynamic model.^[1]

Shape of curveEdit

It shows a steep relationship at relatively low filling pressures and a plateau, where further stretch is not possible and so increases in pressure have little effect on output. The pressures where there is a steep relationship lie within the normal range of right atrial pressure (RAP) found in the healthy human during life. This range is about -1 to +2 mmHg. The higher pressures normally occur only in disease, in conditions such as heart failure, where the heart is unable to pump forward all the blood returning to it and so the pressure builds up in the right atrium and the great veins. Swollen neck veins are often an indicator of this type of heart failure.

At low right atrial pressures this graph serves as a graphic demonstration of the Frank–Starling mechanism,^[2] that is as more blood is returned to the heart, more blood is pumped from it without extrinsic signals.

Changes in the cardiac function curveEdit

In vivo however, extrinsic factors such as an increase in activity of the sympathetic nerves, and a decrease in vagal tone cause the heart to beat more frequently and more forcefully. This alters the cardiac function curve, shifting it upwards. This allows the heart to cope with the required cardiac output at a relatively low right atrial pressure. We get what is known as a family of cardiac function curves, as the heart rate increases before the plateau is reached, and without the RAP having to rise dramatically to stretch the heart more and get the Starling effect.

In vivo sympathetic outflow within the myocardium is probably best described by the time honored description of the sinoatrial tree branching out to Purkinges fibers. Parasympathetic inflow within the myocardium is probably best described by influence of the vagus nerve and spinal accessory ganglia.

ReferencesEdit

^ Brengelmann GL (March 2003). "A critical analysis of the view that right atrial pressure determines venous return". J. Appl. Physiol. 94 (3): 849–59. doi:10.1152/japplphysiol.00868.2002. PMID 12391065.
^ "Cardiac Basic Physiology".

UpToDate Contents

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English Journal

Noninvasive estimation of pulmonary capillary wedge pressure in patients with mitral regurgitation: A speckle tracking echocardiography study.

Kawase Y1, Kawasaki M2, Tanaka R3, Nomura N3, Fujii Y3, Ogawa K3, Sato H4, Miyake T3, Kato T5, Tsunekawa T5, Okubo M3, Tsuchiya K3, Tomita S5, Matsuo H3, Minatoguchi S2.
Journal of cardiology.J Cardiol.2016 Feb;67(2):192-8. doi: 10.1016/j.jjcc.2015.04.012. Epub 2015 Jun 23.
BACKGROUND: Echocardiographic parameters to predict pulmonary capillary wedge pressure (PCWP) in mitral regurgitation (MR) are not yet elucidated. We reported that PCWP could be accurately estimated by novel KT index which is defined as log10[left atrial (LA) emptying function (EF)/LA volume]. We ex
PMID 26116209

Predicting cardiac surgery-associated acute kidney injury: The CRATE score.

Jorge-Monjas P1, Bustamante-Munguira J2, Lorenzo M1, Heredia-Rodríguez M3, Fierro I4, Gómez-Sánchez E3, Hernandez A1, Álvarez FJ4, Bermejo-Martin JF5, Gómez-Pesquera E1, Gómez-Herreras JI3, Tamayo E3.
Journal of critical care.J Crit Care.2016 Feb;31(1):130-8. doi: 10.1016/j.jcrc.2015.11.004. Epub 2015 Nov 6.
PURPOSE: Acute kidney injury (AKI) is a frequent complication after cardiac surgery and is associated with increased mortality. The aim was to design a nondialytic AKI score in patients with previously normal renal function undergoing cardiac surgery.METHODS: Data were collected on 909 patients who
PMID 26700607

Characterization of the relationship between spontaneous locomotor activity and cardiovascular parameters in conscious freely moving rats.

Zaretsky DV1, Zaretskaia MV2, DiMicco JA3.
Physiology & behavior.Physiol Behav.2016 Feb 1;154:60-7. doi: 10.1016/j.physbeh.2015.11.014. Epub 2015 Nov 18.
In freely behaving rats, variations in heart rate (HR) and blood pressure (BP) are coupled closely with changes in locomotor activity (Act). We have attempted to characterize this relationship mathematically. In 10- and 16-week-old rats, HR, BP and Act were recorded telemetrically every minute for 2
PMID 26603274

Japanese Journal

Myocardial Stretch in Early Systole is a Key Determinant of the Synchrony of Left Ventricular Mechanical Activity in vivo

Caracciolo Giuseppe,Goliasch Georg,Amaki Makoto,Bansal Manish,Nakabo Ayumi,Abe Haruhiko,Scott Luis,Lipar Luka,Pedrizzetti Gianni,Narula Jagat,Sengupta Partho P.
Circulation Journal 77(10), 2526-2534, 2013
… Methods and Results: The time intervals from R wave to segmental longitudinal stretch in early systole (Tstretch) and peak shortening (Tpeak) and the respective standard deviations (σTstretch and σTpeak) were measured by speckle-tracking echocardiography in 57 patients undergoing cardiac resynchronization therapy (CRT). …
NAID 130003361823

Estimation of Left Atrial Pump Function by Mitral Annular Velocity

MASUDA Masaharu,IWAKURA Katsuomi,INOUE Koichi,OKAMURA Atsunori,KOYAMA Yasushi,KIMURA Ryusuke,DOI Atsushi,TOYOSHIMA Yuko,KOMURO Issei,FUJII Kenshi
Circulation journal : official journal of the Japanese Circulation Society 76(6), 1430-1435, 2012-05-25
… Background: Estimation of left atrial (LA) pump function is important for the management of cardiac patients. … The purpose of this study is to elucidate the role of mitral annular late diastolic velocity (A') determined by transthoracic echocardiography as a parameter to predict LA pump function. …
NAID 10030316299

Calcium-induced calcium release from the sarcoplasmic reticulum can be evaluated with a half-logistic function model in aequorin-injected cardiac muscles

MIZUNO Ju,HANAOKA Kazuo,OTSUJI Mikiya,ARITA Hideko,SAKAMOTO Hidetoshi,FUKUDA Satoru,SAWAMURA Shigehito
Journal of anesthesia 25(6), 831-838, 2011-12-20
NAID 10030448692

Related Pictures

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★リンクテーブル★

リンク元	「心機能曲線」
関連記事	「function」「curve」「cardiac」

「心機能曲線」

　　[★]

英: ventrivular function curve, cardiac function curve
同: フランク・スターリングの曲線 Frank-Starling curve

SP.

左室拡張終期圧-一回仕事量の関係をプロットした曲線
心拍数に依存しない曲線 (2007年度後期生理学授業プリント)

「function」

　　[★]

n.

機能、(数学)関数、(化学)官能基

survival as a function of HbA1c in people with type 2 diabetes HbA1cの機能を考慮（指標に）した2型糖尿病の患者の生存（予後）

Figure 2A shows survival as a function of device removal during index hpspitalization, censored at 1 year or date of last contact. (Figure2Aはは最初の入院中における心臓デバイス除去に関する生存曲線で退院後1年もしくは最後の接触で打ち切っている)