関: short-chain acyl-CoA dehydrogenase

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the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system

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carbonの化学記号
cobaltの化学記号

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/08/22 01:19:20」(JST)

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In enzymology, a butyryl-CoA dehydrogenase (EC 1.3.99.2) is an enzyme that catalyzes the chemical reaction

butanoyl-CoA + acceptor 2-butenoyl-CoA + reduced acceptor

Thus, the two substrates of this enzyme are butanoyl-CoA and acceptor, whereas its two products are 2-butenoyl-CoA and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is butanoyl-CoA:acceptor 2,3-oxidoreductase. Other names in common use include butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, and butanoyl-CoA:(acceptor) 2,3-oxidoreductase. This enzyme participates in 3 metabolic pathways: fatty acid metabolism, valine, leucine and isoleucine degradation, and butanoate metabolism. It employs one cofactor, FAD.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1BUC and 1JQI.

References

Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 447-466.
MAHLER HR, MACKLER B, GREEN DE (1954). "Studies on metalloflavoproteins. III. Aldehyde oxidase: a molybdoflavoprotein". J. Biol. Chem. 210 (1): 465–80. PMID 13201608.
HAUGE JG, CRANE FL, BEINERT H (1956). "On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. III. Palmityl coA dehydrogenase". J. Biol. Chem. 219 (2): 727–33. PMID 13319294.
MAHLER HR (1954). "Studies on the fatty acid oxidizing system of animal tissues. IV The prosthetic group of butyryl coenzyme A dehydrogenase". J. Biol. Chem. 206 (1): 13–26. PMID 13130522.

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「ブチリルCoAデヒドロゲナーゼ」

butyryl-CoA dehydrogenase
Identifiers
EC number	1.3.99.2
CAS number	9027-88-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search
PMC	articles
PubMed	articles

　　[★]

英: butyryl-CoA dehydrogenase
関: 短鎖アシルCoA脱水素酵素、ブチリルCoA脱水素酵素

「short-chain acyl-CoA dehydrogenase」

　　[★]

短鎖アシルCoA脱水素酵素

関: butyryl-CoA dehydrogenase、SCAD

「ブチリルCoA脱水素酵素」

　　[★]

英: butyryl-CoA dehydrogenase
関: ブチリルCoAデヒドロゲナーゼ

「C」

　　[★]

炭素 carbon
シトシン cytosine
システイン cysteine
シチジン
セルシウス度摂氏 degrees Celsius degree C
産婦人科領域で「子宮外頚子宮外頚部 exocervix」を表現するための略語

「CoA」

　　[★]

「dehydrogenase」

　　[★] 脱水素酵素デヒドロゲナーゼ

「dehydrogenases」