beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

β-N-アセチルグルコサミニル糖ペプチド-β-1

WordNet

1. to remain unmolested, undisturbed, or uninterrupted -- used only in infinitive form; "let her be"
2. work in a specific place, with a specific subject, or in a specific function; "He is a herpetologist"; "She is our resident philosopher" (同)follow
3. have life, be alive; "Our great leader is no more"; "My grandfather lived until the end of war" (同)live
4. be identical to; be someone or something; "The president of the company is John Smith"; "This is my house"
5. happen, occur, take place; "I lost my wallet; this was during the visit to my parents house"; "There were two hundred people at his funeral"; "There was a lot of noise in the kitchen"
6. have the quality of being; (copula, used with an adjective or a predicate noun); "John is rich"; "This is not a good answer"
7. occupy a certain position or area; be somewhere; "Where is my umbrella?" "The toolshed is in the back"; "What is behind this behavior?"
8. spend or use time; "I may be an hour"
9. stake on the outcome of an issue; "I bet $100 on that new horse"; "She played all her money on the dark horse" (同)wager, play
10. the act of gambling; "he did it on a bet" (同)wager
11. maintain with or as if with a bet; "I bet she will be there!" (同)wager
12. second in order of importance; "the candidate, considered a beta male, was perceived to be unable to lead his party to victory"
13. the 2nd letter of the Greek alphabet
14. preliminary or testing stage of a software or hardware product; "a beta version"; "beta software"
15. the 14th letter of the Roman alphabet (同)n

PrepTutorEJDIC

1. 《連結語として補語を伴なって…『である』,…だ,…です / 《位置・場所を表す語句を伴って》(…に)『ある』,いる(occupy a place or situation) / 〈物事が〉『存在する』,ある(exist);〈生物が〉生存する,生きている(live) / 行われる,起こる,発生する(take place, occur) / 存続する,そのままでいる(remain as before) / 《『be to』 do》 / …する予定である,…することになっている / …すべきだ / 《受動態の不定詞を伴って》…できる / 《命令》…するのだ / 《条件節に》…する意図がある / 《『if…were to』 do》…するとしたなら / 《『be』 do『ing』》《進行形》 / 《進行中の動作》…している,しつつある / 《近い未来》…しようとしている,するつもり / 《動作の反復》(いつも)…している / 《『be』+『他動詞の過去分詞』》《受動態》…される,されている / 《『be』+『自動詞の過去分詞』》《完了形》…した[状態にある]
2. 『かけ』・(…との)かけ《+『with』+『名』》 / かけた物(金) / かけの対象 / 〈金・物〉'を'『かける』 / (かけ事・ゲームなどで)〈人〉‘と'『かけをする』《+『名』〈人〉+『on』+『名』》 / (…に)『かける』《+『on』(『against』)+『名』(one's do『ing』)》
3. ベータ(ギリシア語アルファベットの第2文字;B,β;英語のB,b に遭当)
4. nitrogenの化学記号
5. neodymiumの化学記号

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English Journal

• Probing elongating and branching β-D-galactosyltransferase activities in Leishmania parasites by making use of synthetic phosphoglycans.

• Sizova OV1, Ross AJ, Ivanova IA, Borodkin VS, Ferguson MA, Nikolaev AV.Author information 1College of Life Sciences, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, UK.AbstractProtozoan parasites of the genus Leishmania synthesize lipophosphoglycans (LPGs), phosphoglycans and proteophosphoglycans that contain phosphosaccharide repeat units of [-6)Gal(β1-4)Man(α1-OPO(3)H-]. The repeat structures are assembled by sequential addition of Manα1-OPO(3)H and β-Gal. In this study, an UDP-Gal-dependent activity was detected in L. donovani and L. major membranes using synthetic phospho-oligosaccharide fragments of lipophosphoglycan as acceptor substrates. Incubation of a microsomal preparation from L. donovani or L. major parasites with synthetic substrates and UDP-[6-(3)H]Gal resulted in incorporation of radiolabel into these exogenous acceptors. The [(3)H]galactose-labeled products were characterized by degradation into radioactive, low molecular mass fragments upon hydrolysis with mild acid and treatment with β-galactosidases. We showed that the activity detected with L. donovani membranes is the elongating β-d-galactosyltransferase associated with LPG phosphosaccharide backbone biosynthesis (eGalT). The eGalT activity showed a requirement for the presence of at least one phosphodiester group in the substrate and it was enhanced dramatically when two or three phosphodiester groups were present. Using the same substrates we detected two types of galactosyltransferase activity in L. major membranes: the elongating β-d-galactosyltransferase and a branching β-d-galactosyltransferase (bGalT). Both L. major enzymes required a minimum of one phosphodiester group present in the substrate, but acceptors with two or three phosphodiester groups were found to be superior.
• ACS chemical biology.ACS Chem Biol.2011 Jun 17;6(6):648-57. doi: 10.1021/cb100416j. Epub 2011 Apr 11.
• Protozoan parasites of the genus Leishmania synthesize lipophosphoglycans (LPGs), phosphoglycans and proteophosphoglycans that contain phosphosaccharide repeat units of [-6)Gal(β1-4)Man(α1-OPO(3)H-]. The repeat structures are assembled by sequential addition of Manα1-OPO(3)H and β-Gal. In this s
• PMID 21425873

• 4Pi-microscopy of the Golgi apparatus in live mammalian cells.

• Egner A1, Verrier S, Goroshkov A, Söling HD, Hell SW.Author information 1Department of NanoBiophotonics, Max-Planck-Institute for Biophysical Chemistry, High Resolution Optical Microscopy Group, 37077 Goettingen, Germany.AbstractWe report the applicability of 4Pi-microscopy to live mammalian cells. Controlled interference of the counterpropagating wavefronts is possible despite the slight variations in cellular refractive index. Superresolved 3D-fluorescence imaging is exemplified with the first representation of the Golgi apparatus in a live cell at approximately 100 nm resolution.
• Journal of structural biology.J Struct Biol.2004 Jul;147(1):70-6.
• We report the applicability of 4Pi-microscopy to live mammalian cells. Controlled interference of the counterpropagating wavefronts is possible despite the slight variations in cellular refractive index. Superresolved 3D-fluorescence imaging is exemplified with the first representation of the Golgi
• PMID 15109607

• Constitutively active PKB/Akt inhibited apoptosis and down-regulated beta1,4-galactosyltransferase 1 in hepatocarcinoma cells.

• Zhu X1, Chen S, Yin X, Shen A, Ji S, Shen Z, Gu J.Author information 1State Key Laboratory of Genetic Engineering, Gene Research Center, Shanghai Medical College of Fudan University, Shanghai 200032, PR China.AbstractBeta1,4-galactosyltransferase1 (beta1,4GT1) is localized both in the Golgi complex and on the cell surface. In our previous study, we first reported that beta1,4GT1 was associated with cycloheximide-induced apoptosis in human hepatocarcinoma cells. In this study, we transfected constitutively active protein kinase B (Gag-PKB), a central mediator of anti-apoptotic signals transduced by the PI3-kinase, into SMMC-7721 human hepatocarcinoma cells, and examined its effect on apoptosis and beta1,4GT1 activity. Flow cytometry analysis showed that apoptosis was inhibited in Gag-PKB transfected SMMC-7721 cells. At the same time, beta1,4GT1 mRNA level and enzyme activities were downregulated in these cells, consistent with which, the content of beta1,4 Gal branch in the glycoconjugates was decreased in stably transfected cells. Cotransfection of beta1,4GT1 promoter/luciferase reporter and Gag-PKB decreased the luciferase reporter activity in a dose-dependent manner, indicating that the differences in mRNA levels might be regulated through promoter function. All these findings suggested that changes of beta1,4GT1 activity might be involved in apoptotic pathway in hepatocarcinoma cells.
• Biochemical and biophysical research communications.Biochem Biophys Res Commun.2003 Sep 19;309(2):279-85.
• Beta1,4-galactosyltransferase1 (beta1,4GT1) is localized both in the Golgi complex and on the cell surface. In our previous study, we first reported that beta1,4GT1 was associated with cycloheximide-induced apoptosis in human hepatocarcinoma cells. In this study, we transfected constitutively active
• PMID 12951046

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★リンクテーブル★

リンク元	「β-N-アセチルグルコサミニル糖ペプチド-β-1,4-ガラクトシルトランスフェラーゼ」
関連記事	「galactosyltransferase」「n」「N」「beta」「be」

「β-N-アセチルグルコサミニル糖ペプチド-β-1,4-ガラクトシルトランスフェラーゼ」

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英

beta-N-acetylglucosaminylglycopeptide beta-1

• beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

「galactosyltransferase」

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ガラクトース転移酵素、ガラクトシルトランスフェラーゼ、ガラクトシル基転移酵素

「n」

　　[★]

• n.

• 例数

関

number of experiment、sample size

• pの前の[n]はmと記載する。synptom→symptom

「N」

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• アスパラギン asparagine
• 窒素(原子、分子)

　 　

「beta」

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β、ベータ 　 　 　 　

「be」

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