WordNet

staining readily with basic dyes
a leukocyte with basophilic granules easily stained by basic stains (同)basophile

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/29 18:42:35」(JST)

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A Basophil granulocyte stains dark purple upon H&E staining.

Basophilic is a technical term used by histologists. It describes the microscopic appearance of cells and tissues, as seen down the microscope, after a histological section has been stained with a dye attracted to basic molecules. The most common such dye is haematoxylin.

Basophilic describes the appearance of structures seen in histological sections which take up basic dyes. The structures usually stained are those that contain negative charges, such as the phosphate backbone of DNA in the cell nucleus and ribosomes.

Basophils are cells that "love" the blue, and usually show up deep blue under standard staining techniques (H&E). Specifically, this term refers to:

basophil granulocytes
anterior pituitary basophils

Different definitions will apply to basophilic:

Basophilic stains are acidic stains called base loving stains. Basophilic cells are base loving cells. Basophilic cells attract base dyes, such as hematoxylin; however, 'Eosin' is referred to as an basophilic stain.

Simplistically, acid pH stains (positive charge) are attracted to the base pH tissue(negative charge), so they are called basophilic stains. Eosinophils (base components that like acids) are dyed red by the basophilic stain or acid stain, eosin. Basophils(acid that like base components) are dyed blue by the acidophilic or basic stain, hematoxylin.

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English Journal

Multiple pilomatricomas with somatic CTNNB1 mutations in children with constitutive mismatch repair deficiency.

Chmara M, Wernstedt A, Wasag B, Peeters H, Renard M, Beert E, Brems H, Giner T, Bieber I, Hamm H, Sciot R, Wimmer K, Legius E.SourceDepartment of Human Genetics, KU Leuven, University Hospitals Leuven, Leuven, Belgium; Department of Biology and Genetics, Medical University of Gdansk, Gdansk, Poland.
Genes, chromosomes & cancer.Genes Chromosomes Cancer.2013 Jul;52(7):656-64. doi: 10.1002/gcc.22061. Epub 2013 Apr 30.
Constitutional mismatch repair deficiency (CMMR-D) due to biallelic germline mutations in one of four mismatch repair genes causes a childhood cancer syndrome characterized by a broad tumor spectrum including hematological malignancies, and brain and Lynch syndrome-associated tumors. Herein, we repo
PMID 23629955

Identification and characterization of a novel adenovirus in the cloacal bursa of gulls.

Bodewes R, van de Bildt MW, Schapendonk CM, van Leeuwen M, van Boheemen S, de Jong AA, Osterhaus AD, Smits SL, Kuiken T.SourceDepartment of Viroscience, Erasmus Medical Centre, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.
Virology.Virology.2013 May 25;440(1):84-8. doi: 10.1016/j.virol.2013.02.011. Epub 2013 Mar 16.
Several viruses of the family of Adenoviridae are associated with disease in birds. Here we report the detection of a novel adenovirus in the cloacal bursa of herring gulls (Larus argentatus) and lesser black-backed gulls (Larus fuscus) that were found dead in the Netherlands in 2001. Histopathologi
PMID 23507452

Most Nonparotid "Acinic Cell Carcinomas" Represent Mammary Analog Secretory Carcinomas.

Bishop JA, Yonescu R, Batista D, Eisele DW, Westra WH.SourceDepartments of *Pathology †Otolaryngology/Head and Neck Surgery ‡Oncology, The Johns Hopkins Medical Institutions, Baltimore, MD.
The American journal of surgical pathology.Am J Surg Pathol.2013 May 15. [Epub ahead of print]
Acinic cell carcinoma (ACC) is a low-grade salivary gland malignancy characterized by serous acinar differentiation. Most ACCs arise in the parotid gland, but ACCs have been reported to originate in nonparotid salivary glands where serous acini are less abundant. Given the recent discovery of mammar
PMID 23681074

Japanese Journal

タツノオトシゴHippocampus kelloggiエタノール抽出物のラット好塩基球細胞株RBL-2H3細胞における脱顆粒抑制効果

伊藤智広,阪田雄大,吉田ゆに華 [他]
日本水産学会誌 79(4), 683-693, 2013-07
NAID 40019772919

Gene expression analysis of cartilage-like components in pleomorphic adenoma

Kokubu Mayu,Tominaga Kazuya,Tanaka Akio
Journal of Osaka Dental University 47(1), 67-74, 2013-04
… The chondroid structure consists of chondrocyte-like cells that are associated with the cartilage lacunae of the basophilic matrix. …
NAID 110009603280

漢方生薬「川〓(Cnidii Rhizoma)」の抗アレルギー作用とその活性成分について

渥美聡孝,福村基徳,河崎亮一,平井康昭,鳥居塚和生
生薬學雜誌 67(1), 7-12, 2013-02-20
… In this study, we investigated the anti-allergic activities of Cnidii Rhizoma in cultured Rat Basophilic Leukemia cells (RBL-2H3). …
NAID 110009577731

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★リンクテーブル★

リンク元	「好塩基性」「塩基好性」「好塩基」「好塩基球性」
拡張検索	「acute basophilic leukemia」「basophilic progenitor cell」