alpha-keto acid dehydrogenase

α-ケト酸デヒドロゲナーゼ

WordNet

1. first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
2. the 1st letter of the Greek alphabet
3. the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
4. early testing stage of a software or hardware product; "alpha version"
5. street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
6. any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
7. having the characteristics of an acid; "an acid reaction"
8. any high mountain

PrepTutorEJDIC

1. アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
2. 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
3. 高山,高峰

UpToDate Contents

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• 1. 先天性代謝異常：代謝性救急疾患 inborn errors of metabolism metabolic emergencies
• 2. 脂質およびプリン代謝障害による代謝性ミオパチー metabolic myopathies caused by disorders of lipid and purine metabolism
• 3. メープルシロップ尿症の概要 overview of maple syrup urine disease
• 4. Uncommon congenital adrenal hyperplasias
• 5. 遺伝性腎癌症候群 hereditary kidney cancer syndromes

English Journal

• Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis.

• Mesa J1, Alsina C1, Oppermann U2, Parés X1, Farrés J1, Porté S3.
• Chemico-biological interactions.Chem Biol Interact.2015 Jun 5;234:105-13. doi: 10.1016/j.cbi.2015.01.021. Epub 2015 Jan 22.
• Prostaglandins (PGs) are lipid compounds derived from arachidonic acid by the action of cyclooxygenases, acting locally as messenger molecules in a wide variety of physiological processes, such as inflammation, cell survival, apoptosis, smooth muscle contraction, adipocyte differentiation, vasodilat
• PMID 25619643

• Investigation of inflammatory profile in MSUD patients: benefit of L-carnitine supplementation.

• Mescka CP1, Guerreiro G, Donida B, Marchetti D, Wayhs CA, Ribas GS, Coitinho AS, Wajner M, Dutra-Filho CS, Vargas CR.
• Metabolic brain disease.Metab Brain Dis.2015 May 24. [Epub ahead of print]
• Maple Syrup Urine Disease (MSUD) is a metabolic disorder caused by a severe deficiency of the branched-chain α-keto acid dehydrogenase complex activity which leads to the accumulation of branched-chain amino acids (BCAA) leucine (Leu), isoleucine and valine and their respective α-keto-acids in bod
• PMID 26002427

• 1-Heteroaryl-3-phenoxypropan-2-ones as inhibitors of cytosolic phospholipase A₂α and fatty acid amide hydrolase: Effect of the replacement of the ether oxygen with sulfur and nitrogen moieties on enzyme inhibition and metabolic stability.

• Sundermann T1, Fabian J1, Hanekamp W1, Lehr M2.
• Bioorganic & medicinal chemistry.Bioorg Med Chem.2015 May 15;23(10):2579-92. doi: 10.1016/j.bmc.2015.03.033. Epub 2015 Mar 21.
• Cytosolic phospholipase A2α (cPLA2α) and fatty acid amide hydrolase (FAAH) are enzymes, which have emerged as attractive targets for the development of analgesic and anti-inflammatory drugs. We recently reported that certain 3-phenoxy-substituted 1-heteroarylpropan-2-ones are inhibitors of cPLA2α
• PMID 25862211

Japanese Journal

• Activation of hepatic branched-chain alpha-keto acid dehydrogenase complex by tumor necrosis factor-alpha in rats

• Biochem Biophys Res Commun 328, 973-978, 2005
• NAID 80017210378

• 250.急性運動による分岐鎖アミノ酸代謝の促進 : branched-chain alpha-keto acid dehydrogenase(BCKDH)の活性化機構(【代謝】)

• 体力科學 50(6), 857, 2001-12-01
• NAID 110001920000

• Interaction of protein domains in the assembly and mechanism of 2-oxo acid dehydrogenase multienzyme complex.

• Alpha
• NAID 10005843236

Related Links

• BCKDHA - branched chain keto acid dehydrogenase E1 ...

The official name of this gene is “branched chain keto acid dehydrogenase E1, alpha polypeptide.” BCKDHA is the gene's official symbol. The BCKDHA gene is also known by other names, listed below. Read more about ...

• Alpha-Keto acid dehydrogenase complexes, V ...

Alpha-Keto acid dehydrogenase complexes, V. Macromolecular organization of pyruvate and alpha-ketoglutarate dehydrogenase complexes isolated from beef kidney ... Full text is available as a scanned copy of the original print ...

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★リンクテーブル★

リンク元	「α-ケト酸デヒドロゲナーゼ」「αケト酸デヒドロゲナーゼ」「3-methyl-2-oxobutanoate dehydrogenase」
関連記事	「alpha」「dehydrogenase」「dehydrogenases」「keto acid」

「α-ケト酸デヒドロゲナーゼ」

　　[★]

英

alpha-keto acid dehydrogenase 3-methyl-2-oxobutanoate dehydrogenase

同

α-ケト酸脱水素酵素

関

[[]]

• ビタミンB1要求性αケト酸代謝系酵素
• 2-オキソ酪酸 + CoASH + NAD⁺ －(α-ケト酸デヒドロゲナーゼ)→　プロピオニルCoA + NADH + CO₂

「αケト酸デヒドロゲナーゼ」

　　[★]

英

alpha-keto acid dehydrogenase

関

3-メチル-2-オキソブタン酸デヒドロゲナーゼ、αケト酸脱水素酵素、α-ケト酸脱水素酵素、α-ケト酸デヒドロゲナーゼ

「3-methyl-2-oxobutanoate dehydrogenase」

　　[★]

3-メチル-2-オキソブタン酸脱水素酵素、3-メチル-2-オキソブタン酸デヒドロゲナーゼ

関

alpha-keto acid dehydrogenase

「alpha」

　　[★]

α、アルファ

関

alfa

　 　 　 　 　

「dehydrogenase」

　　[★] 脱水素酵素 デヒドロゲナーゼ

「dehydrogenases」

　　[★] 脱水素酵素 デヒドロゲナーゼ

「keto acid」

　　[★]

ケト酸

関

ketoacid