3-メチル-2-オキソブタン酸脱水素酵素、3-メチル-2-オキソブタン酸デヒドロゲナーゼ
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/27 11:35:14」(JST)
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) | |||||||||
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| Identifiers | |||||||||
| EC number | 1.2.4.4 | ||||||||
| CAS number | 9082-72-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a 3-methyl-2-oxobutanoate dehydrogenase (EC 1.2.4.4) is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are 3-methyl-2-oxobutanoate, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, and lipoyllysine, whereas its 3 products are dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, S-(2-methylpropanoyl)dihydrolipoyllysine, and CO2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with a disulfide as acceptor.
This enzyme participates in valine, leucine and isoleucine degradation. It employs one cofactor, thiamin diphosphate.
As of late 2007, 29 structures have been solved for this class of enzymes, with PDB accession codes 1DTW, 1OLS, 1OLU, 1OLX, 1U5B, 1UM9, 1UMB, 1UMC, 1UMD, 1V11, 1V16, 1V1M, 1V1R, 1WCI, 1X7W, 1X7X, 1X7Y, 1X7Z, 1X80, 2BEU, 2BEV, 2BEW, 2BFB, 2BFC, 2BFD, 2BFE, 2BFF, 2BP7, and 2J9F.
This EC 1.2 enzyme-related article is a stub. You can help Wikipedia by expanding it.
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| リンク元 | 「α-ケト酸デヒドロゲナーゼ」「3-メチル-2-オキソブタン酸デヒドロゲナーゼ」「3-メチル-2-オキソブタン酸脱水素酵素」 |
| 関連記事 | 「dehydrogenase」「dehydrogenases」 |