alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

α-アミノ-3-ヒドロキシ-5-メチル-4-イソキサゾールプロピオン酸

関

AMPA

WordNet

1. first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
2. the 1st letter of the Greek alphabet
3. the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
4. early testing stage of a software or hardware product; "alpha version"
5. street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
6. any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
7. having the characteristics of an acid; "an acid reaction"
8. pertaining to or containing any of a group of organic compounds of nitrogen derived from ammonia (同)aminic
9. the radical -NH2 (同)amino_group
10. being or containing a hydroxyl group
11. the univalent radical CH3- derived from methane (同)methyl_group, methyl radical

PrepTutorEJDIC

1. アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
2. 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD

UpToDate Contents

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English Journal

• Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease.

• Gaisler-Salomon I1, Kravitz E2, Feiler Y3, Safran M3, Biegon A4, Amariglio N3, Rechavi G5.
• Neurobiology of aging.Neurobiol Aging.2014 Aug;35(8):1785-91. doi: 10.1016/j.neurobiolaging.2014.02.018. Epub 2014 Mar 1.
• Adenosine to inosine (A-to-I) RNA editing is a base recoding process within precursor messenger RNA, catalyzed by members of the adenosine deaminase acting on RNA (ADAR) family. A notable example occurs at the Q/R site of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptor s
• PMID 24679603

• Isoflurane unveils a critical role of glutamate transporter type 3 in regulating hippocampal GluR1 trafficking and context-related learning and memory in mice.

• Cao J1, Wang Z2, Mi W3, Zuo Z4.
• Neuroscience.Neuroscience.2014 Jul 11;272:58-64. doi: 10.1016/j.neuroscience.2014.04.049. Epub 2014 May 4.
• Glutamate transporter type 3 (EAAT3) may play a role in cognition. Isoflurane enhances EAAT3 trafficking to the plasma membrane. Thus, we used isoflurane to determine how EAAT3 might regulate learning and memory and the trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors,
• PMID 24797327

• Decreased pain threshold and enhanced synaptic transmission in the anterior cingulate cortex of experimental hypothyroidism mice.

• Yi J, Zheng JY, Zhang W, Wang S, Yang ZF, Dou KF.
• Molecular pain.Mol Pain.2014 Jun 18;10(1):38. [Epub ahead of print]
• BACKGROUND: Thyroid hormones are essential for the maturation and functions of the central nervous system. Pain sensitivity is related to the thyroid status. However, information on how thyroid hormones affect pain processing and synaptic transmission in the anterior cingulate cortex (ACC) is limite
• PMID 24943008

Japanese Journal

• Inhibitory Effects of Acorn Extract on Glutamate-Induced Calcium Signaling in Cultured Rat Hippocampal Neurons

• , , [他], , ,
• Biological and Pharmaceutical Bulletin 36(3), 331-338, 2013
• … Acorn extract significantly inhibited (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) (30 µM)-induced [Ca2+]i increases. … Acorn extract also significantly inhibited N-methyl-D-aspartate (100 µM)-induced [Ca2+]i increases. …
• NAID 130003382074

• Effects of Quercetin on Human .ALPHA.-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor-Mediated Ion Currents

• , , [他], , , , , , , , , ,
• Biological and Pharmaceutical Bulletin 33(9), 1615-1619, 2010
• … The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor is one of several excitatory receptors, which play an important role in postsynaptic neurotransmission. …
• NAID 130000322366

• Growth factor-mediated Fyn signaling regulates alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor expression in rodent neocortical neurons

• NARISAWA-SAITO M.
• Proc Natl Acad Sci USA 96, 2461-2466, 1999
• NAID 80010997186

Related Links

• The molecular pharmacology and cell biology of alpha-amino ...

1. Pharmacol Rev. 2005 Jun;57(2):253-77. The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Palmer CL, Cotton L, Henley JM. Medical Research Council ...

• Effects of Quercetin on Human .ALPHA.-Amino-3-hydroxy-5 ...

Effects of Quercetin on Human .ALPHA.-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor-Mediated Ion Currents Shin Tae-Joon Shin Tae-Joon Department of Physiology, College of Veterinary Medicine and Bio ...

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★リンクテーブル★

リンク元	「α-アミノ-3-ヒドロキシ-5-メチル-4-イソキサゾールプロピオン酸」
関連記事	「hydroxy」「isoxazolepropionic acid」「alpha」「hydro」

「α-アミノ-3-ヒドロキシ-5-メチル-4-イソキサゾールプロピオン酸」

　　[★]

英

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid、AMPA

「hydroxy」

　　[★]

ヒドロキシ、ハイドロキシ、水酸化

関

hydroxylation

　

「isoxazolepropionic acid」

　　[★]

• イソキサゾールプロピオン酸

関

isoxazolepropionate

「alpha」

　　[★]

α、アルファ

関

alfa

　 　 　 　 　

「hydro」

　　[★] ヒドロ、ハイドロ