WordNet

undergo a test; "She doesnt test well"
any standardized procedure for measuring sensitivity or memory or intelligence or aptitude or personality etc; "the test was standardized on a large sample of students" (同)mental test, mental testing, psychometric test
the act of undergoing testing; "he survived the great test of battle"; "candidates must compete in a trial of skill" (同)trial
the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial" (同)trial, run
a hard outer covering as of some amoebas and sea urchins
put to the test, as for its quality, or give experimental use to; "This approach has been tried with good results"; "Test this recipe" (同)prove, try, try out, examine, essay
achieve a certain score or rating on a test; "She tested high on the LSAT and was admitted to all the good law schools"
determine the presence or properties of (a substance)
show a certain characteristic when tested; "He tested positive for HIV"
an examination of the characteristics of something; "there are laboratories for commercial testing"; "it involved testing thousands of children for smallpox"
the act of subjecting to experimental test in order to determine how well something works; "they agreed to end the testing of atomic weapons"
tested and proved useful or correct; "a tested method" (同)tried, well-tried
tested and proved to be reliable (同)time-tested, tried, tried and true
the inner pale yellow part of the lenticular nucleus (同)globus_pallidus, paleostriatum
spirochete that causes disease in humans (e.g. syphilis and yaws)

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(人の能力などの)『試験』,考査,テスト / (物事の)『試験』,検済,試錬,実験《+of+名》 / 化学分析;試薬 / =test match / …‘を'『試験する』,検査する / …‘を'化学分析する / (…の)試験を受ける,試験をする《+for+名》

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1. 梅毒の診断的検査 diagnostic testing for syphilis
2. 妊娠中の梅毒 syphilis in pregnancy
3. 先天梅毒：臨床的特徴および診断 congenital syphilis clinical features and diagnosis
4. 先天梅毒：評価、管理、および予防 congenital syphilis evaluation management and prevention
5. HIV感染患者における梅毒の疫学、臨床症状、および診断 epidemiology clinical presentation and diagnosis of syphilis in the hiv infected patient

English Journal

Use of the INNO-LIA syphilis score assay in the resolution of discordant positive screening enzyme immunoassay results for the serological diagnosis of syphilis.

Lam T, Lau H, Lee Y, Fung S, Leung W, Kam K.Author information Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, Hong Kong.AbstractWe studied the use of the INNO-LIA syphilis score assay in the resolution of discordant positive screening results of the Murex ICE Syphilis enzyme immunoassay (EIA) with the confirmatory results of both the Serodia Treponema pallidum particle agglutination (TPPA) and the fluorescent treponemal antibody-absorption (FTA-Abs) assays, for the serological diagnosis of syphilis. This was an observational study on the serum samples received by the Syphilis Laboratory, Hong Kong, during the period from January 2006 to December 2012. A total of 801 serum samples with discordant positive screening EIA results were used. Consensus results of such serum samples were derived from results of the EIA, TPPA and FTA-abs assays. The age range of the individuals was 14 to 104 years (median of 52). There were 369 males and 432 females. Of 378 serum samples, 139 showed agreement among positive results, 23 of 310 showed agreement among indeterminate results and 277 of 465 showed agreement among negative results. The proportions of agreement among positive, indeterminate and negative results were 0.37 (95% CI 0.32-0.42), 0.07 (95% CI 0.05-0.11) and 0.60 (95% CI 0.55-0.64), respectively; kappa 0.55 (95% CI 0.49-0.60). There were 60 serum samples with positive consensus results but negative INNO-LIA syphilis score results and 10 with negative consensus results but positive INNO-LIA syphilis score results. Although the INNO-LIA syphilis score assay can be considered a valid alternative confirmatory test for the serological diagnosis of syphilis, the present study showed that its use in the resolution of discordant positive screening EIA results was moderate. A more extensive characterization of serum samples with discordant reactive screening treponemal test results is necessary.
International journal of STD & AIDS.Int J STD AIDS.2014 Jan;25(1):52-6. doi: 10.1177/0956462413491938. Epub 2013 Jul 19.
We studied the use of the INNO-LIA syphilis score assay in the resolution of discordant positive screening results of the Murex ICE Syphilis enzyme immunoassay (EIA) with the confirmatory results of both the Serodia Treponema pallidum particle agglutination (TPPA) and the fluorescent treponemal anti
PMID 23970631

Improved Reverse Screening Algorithm for Treponema pallidum Antibody Using Signal-to-Cutoff Ratios from Chemiluminescence Microparticle Immunoassay.

Dai S, Chi P, Lin Y, Zheng X, Liu W, Zhang J, Zeng Q, Wu X, Liu W, Wang J.Author information From the *State Key Laboratory of Oncology in South China and Departments of †Clinical Laboratory and ‡Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.AbstractBACKGROUND: The widespread reverse syphilis screening algorithm involves 1 more treponemal test than the traditional screening algorithm, resulting in increased medical costs. In the first screening step of the algorithm, a chemiluminescence microparticle immunoassay is used to detect Treponema pallidum (TP) antibody on the basis of signal-to-cutoff (S/CO) ratios. We hypothesized that by analyzing S/CO ratios, we could determine a strategy to reduce unnecessary confirmatory testing.
Sexually transmitted diseases.Sex Transm Dis.2014 Jan;41(1):29-34. doi: 10.1097/OLQ.0000000000000066.
BACKGROUND: The widespread reverse syphilis screening algorithm involves 1 more treponemal test than the traditional screening algorithm, resulting in increased medical costs. In the first screening step of the algorithm, a chemiluminescence microparticle immunoassay is used to detect Treponema pall
PMID 24326578

Use of cerebrospinal fluid enzyme immunoassay for diagnosis of neurosyphilis.

Chan Y, Yeung KH, Ho HF, Ho KM, Lam ET, Leung WL, Kam KM.Author information Social Hygiene Service, Centre for Health Protection, Department of Health, Hong Kong Special Administrative Region, Hong Kong.AbstractBackgroundNeurosyphilis is a difficult clinical stage of syphilis as there is no ideal method for diagnosis and workup requires lumbar puncture which may sometimes provide ambiguous results especially in HIV co-infected patients. Enzyme immunoassay is a widely used screening test for syphilis in serum, its test performance was not well studied in cerebrospinal fluid.AimTo examine the diagnostic performance of cerebrospinal fluid-enzyme immunoassay in neurosyphilis.MethodsThis is a prospective study with a time span of two years. All consecutive patients admitted for workup of neurosyphilis under the Social Hygiene Service, the major public service provider of sexually transmitted disease in Hong Kong, were included. Laboratory tests on cerebrospinal fluid included venereal disease research laboratory, fluorescent treponemal antibody-absorption, Treponema pallidum particle agglutination, enzyme immunoassay syphilis, cerebrospinal fluid cell count, and protein. Performances of the above tests were evaluated and compared using The International Union Against Sexually Transmitted Infections 2008 guidelines.ResultsForty-five patients were prospectively recruited, of which 29 people were living with HIV / AIDS. Using diagnostic case definition standard stipulated in The International Union Against Sexually Transmitted Infections 2008 guidelines, 17 patients satisfied the diagnosis of neurosyphilis. Cerebrospinal fluid-enzyme immunoassay test provided 100% in both sensitivity and negative predictive value, specificity was 46.4% (13/28, 95% CI 31.8-61%). Specificity improved to 80.8% (95% CI: 68.4-93.2%) with optical density cut-off value at 1.4 for cases with cerebrospinal fluid-red cell counts <600/mm3.ConclusionsThis is the first study on use of cerebrospinal fluid-enzyme immunoassay in neurosyphilis. Cerebrospinal fluid-enzyme immunoassay showed high sensitivity and high negative predictive value in the study population. cerebrospinal fluid-RBC less than 600/mm3 may not affect its accuracy.
International journal of STD & AIDS.Int J STD AIDS.2013 Dec 11. [Epub ahead of print]
BackgroundNeurosyphilis is a difficult clinical stage of syphilis as there is no ideal method for diagnosis and workup requires lumbar puncture which may sometimes provide ambiguous results especially in HIV co-infected patients. Enzyme immunoassay is a widely used screening test for syphilis in ser
PMID 24334293