Skp1-cullin-F-box protein

;関:SCF ubiquitin ligase

関

SCF ubiquitin ligase、Skp cullin F-box protein ligase

• Skp cullin F-box protein ligase

WordNet

1. the quantity contained in a box; "he gave her a box of chocolates" (同)boxful
2. evergreen shrubs or small trees (同)boxwood
3. a rectangular drawing; "the flowchart contained many boxes"
4. hit with the fist; "Ill box your ears!"
5. the drivers seat on a coach; "an armed guard sat in the box with the driver" (同)box_seat
6. private area in a theater or grandstand where a small group can watch the performance; "the royal box was empty" (同)loge
7. a (usually rectangular) container; may have a lid; "he rummaged through a box of spare parts"
8. a blow with the hand (usually on the ear); "I gave him a good box on the ear"
9. any one of several designated areas on a ball field where the batter or catcher or coaches are positioned; "the umpire warned the batter to stay in the batters box"
10. separate partitioned area in a public place for a few people; "the sentry stayed in his box to avoid the cold"
11. put into a box; "box the gift, please" (同)package
12. engage in a boxing match
13. remove something that has been rejected; "cull the sick members of the herd"
14. the person or thing that is rejected or set aside as inferior in quality (同)reject
15. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
16. enclosed in or set off by a border or box; "boxed sections of the report"; "boxed announcements in the newspaper"
17. enclosed in or as if in a box; "boxed cigars"; "a confining boxed-in space"; "felt boxed in by the traffic" (同)boxed-in, boxed in
18. fighting with the fists (同)pugilism, fisticuffs

PrepTutorEJDIC

1. 『箱』 / (の…)『1箱』《+『of』+『名』》 / (劇場などの)さじき席 ます席 / 番小屋,詰め所 / (野球で)バッターボックス;コーチャーズボックス;ピッチャーズマウンド;キャッチャーの定位置 / (線で囲った)四角のわく,囲み;(新聞・雑誌の) / (郵便の)私書箱 / 《the box》《英俗》テレビ / …'を'箱に入れる,箱詰めにする
2. 〈C〉(平手・こぶしの)びんた,張り手,ひと打ち / 〈人〉‘と'ボクシングをする / …'を'平手で打つ,こぶしでなぐる / (…と)ボクシングをする《+『with』(『against』)+『名』》
3. 〈C〉〈U〉ツゲ(常緑低木) / 〈U〉=boxwood
4. 〈花など〉'を'摘む / 〈最上のもの〉'を'選び取る / 〈粗悪なもの〉'を'淘汰(とうた)する,〈劣っているもの〉'を'えり分けて殺す / えり出された劣等品(きず物の果物など)
5. 蛋白(たんばく)質
6. 『ボクシング』

UpToDate Contents

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English Journal

• Hsp27 and F-box protein β-TrCP promote degradation of mRNA decay factor AUF1.

• Li ML, Defren J, Brewer G.SourceDepartment of Biochemistry & Molecular Biology, Robert Wood Johnson Medical School-University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA.
• Molecular and cellular biology.Mol Cell Biol.2013 Mar 25. [Epub ahead of print]
• Activation of MAP-pathway kinases p38 and MK2 induces phosphorylation of chaperone Hsp27 and stabilization of mRNAs containing AU-rich elements (AREs). Likewise, expression of phosphomimetic mutant forms of Hsp27 also stabilizes ARE-mRNAs. It appears to perform this function by promoting degradation
• PMID 23530064

• SKP1-like-related genes interact with various F-box proteins and may form SCF complexes with Cullin-F-box proteins in wheat.

• Hong MJ, Kim DY, Seo YW.SourceDivision of Biotechnology, Korea University, Anam-Dong, Seongbuk-Gu, Seoul, 136-701, Republic of Korea.
• Molecular biology reports.Mol Biol Rep.2013 Feb;40(2):969-81. doi: 10.1007/s11033-012-2139-1. Epub 2012 Oct 14.
• S-phase kinase-associated protein 1 (SKP1), a core component of the SKP1-Cullin-F-box (SCF) E3 ubiquitin ligase complex, functions as an adaptor protein, connecting cullin and F-box proteins. SKP1 plays crucial roles in cell-cycle progression, transcriptional regulation, flower formation, signal tra
• PMID 23065282

Japanese Journal

• Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest

• BMC cancer 12, 321, 2012-07
• NAID 120004898305

• Inverse correlation between Skp2 and p27(Kip1) in normal endometrium and endometrial carcinoma

• GYNECOLOGICAL ENDOCRINOLOGY 26(3), 220-229, 2010-03
• NAID 120002598960

• Deregulation of Anaphase-promoting Complex/cyclosome-dependent Proteolysis in Cancer

• Journal of Oral Biosciences 52(4), 388-401, 2010
• NAID 130004475724

Related Links

• Characterization of the cullin and F-box protein partner Skp1

Characterization of the cullin and F-box protein partner Skp1 Raymond W.M. Ng, Talha Arooz, Cain H. Yam, Iris W.Y. Chan, Anita W.S. Lau, Randy Y.C. Poon Department of Biochemistry, Hong Kong University of Science and ...

• Skp1-Cullin-F-box-dependent degradation of Aah1p requires its ...

1. J Biol Chem. 2007 Jul 13;282(28):20097-103. Epub 2007 May 21. Skp1-Cullin-F-box-dependent degradation of Aah1p requires its interaction with the F-box protein Saf1p. Escusa S, Laporte D, Massoni A, Boucherie H, Dautant A ...

Related Pictures

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★リンクテーブル★

リンク元	「Skp cullin F-box protein ligase」「SCF ubiquitin ligase」
関連記事	「cull」「box」「F」

「Skp cullin F-box protein ligase」

　　[★]

SKP・カリン・Fボックスタンパク質リガーゼ

関

SCF ubiquitin ligase、Skp1-cullin-F-box protein

「SCF ubiquitin ligase」

　　[★]

SCFユビキチンリガーゼ

関

Skp cullin F-box protein ligase、Skp1-cullin-F-box protein

「cull」

　　[★]

• 選別する

関

filter、filtering、screen、screening、sort、sorting

　 　 　

「box」

　　[★]

• 箱、ボックス

　 　 　 　 　 　 　 　 　 　 　 　 　 　 　

「F」

　　[★] フェニルアラニン phenylalanine