- 同
- phosphoribosylpyrophosphate
PrepTutorEJDIC
- public relations
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production.
- Zakataeva NP, Romanenkov DV, Skripnikova VS, Vitushkina MV, Livshits VA, Kivero AD, Novikova AE.SourceAjinomoto-Genetika Research Institute, 1-st Dorozhny Proezd, b.1-1, Moscow, 117545, Russia. natalia_zakataeva@agri.ru
- Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2012 Mar;93(5):2023-33. doi: 10.1007/s00253-011-3687-3. Epub 2011 Nov 15.
- Bacillus strains are used for the industrial production of the purine nucleosides inosine and guanosine, which are raw materials for the synthesis of the flavor enhancers disodium inosinate and disodium guanylate. An important precursor of purine nucleosides is 5-phospho-α-D: -ribosyl-1-pyrophospha
- PMID 22083279
- Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS-I.
- Moran R, Kuilenburg AB, Duley J, Nabuurs SB, Retno-Fitri A, Christodoulou J, Roelofsen J, Yntema HG, Friedman NR, van Bokhoven H, de Brouwer AP.SourceCleveland Clinic Foundation, Genomic Medicine Institute, Cleveland, Ohio, USA.
- American journal of medical genetics. Part A.Am J Med Genet A.2012 Feb;158A(2):455-60. doi: 10.1002/ajmg.a.34428. Epub 2012 Jan 13.
- We identified a novel missense mutation, c.424G>C (p.Val142Leu) in PRPS1 in a patient with uric acid overproduction without gout but with developmental delay, hypotonia, hearing loss, and recurrent respiratory infections. The uric acid overproduction accompanying this combination of symptoms sugg
- PMID 22246954
- The PRPP synthetase spectrum: what does it demonstrate about nucleotide syndromes?
- Duley JA, Christodoulou J, de Brouwer AP.SourceUniversity of Queensland and Mater Medical Research Institute, Brisbane, Australia. jduley@pharmacy.uq.edu.au
- Nucleosides, nucleotides & nucleic acids.Nucleosides Nucleotides Nucleic Acids.2011 Dec;30(12):1129-39. doi: 10.1080/15257770.2011.591747.
- Defects in X-linked phosphoribosylpyrophosphate synthetase 1 (PRPS1) manifest as follows: (1) PRS-I enzyme "superactivity" (gain-of-function mutations affecting allosteric regions); (2) PRS-I overexpression (which may be linked to miRNA mutation); (3) severe PRS-I deficiency/Arts syndrome (missense
- PMID 22132967
★リンクテーブル★
[★]
[★]
[★]
- 関
- ligase、synthase
[★]
ホスホリボシルピロリン酸合成酵素
- 同
- 5-phosphoribosyl-l-pyrophosphate
[★]
5-ホスホリボシル1α-ニリン酸