原発開放隅角緑内障
- 関
- primary open-angle glaucoma
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English Journal
- Vessel Caliber in Normal Tension and Primary Open Angle Glaucoma Eyes With Hemifield Damage.
- Rao A1, Agarwal K, Mudunuri H, Padhy D, Roy AK, Mukherjee S.
- Journal of glaucoma.J Glaucoma.2017 Jan;26(1):46-53. doi: 10.1097/IJG.0000000000000498.
- PURPOSE OF THE STUDY: The purpose of the study was to evaluate retinal vessel diameter in age-matched normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) eyes with hemifield involvement.METHODS: Fundus photographs of patients with hemifield defect, good visibility of retinal nerve f
- PMID 27636594
- Myocilin Predictive Genetic Testing for Primary Open-Angle Glaucoma Leads to Early Identification of At-Risk Individuals.
- Souzeau E1, Tram KH1, Witney M1, Ruddle JB2, Graham SL3, Healey PR4, Goldberg I4, Mackey DA5, Hewitt AW6, Burdon KP7, Craig JE8.
- Ophthalmology.Ophthalmology.2016 Dec 16. pii: S0161-6420(16)32004-8. doi: 10.1016/j.ophtha.2016.11.011. [Epub ahead of print]
- PURPOSE: To assess the difference in severity of disease in primary open-angle glaucoma (POAG) patients with a Myocilin (MYOC) disease-causing variant who presented through normal clinical pathways (Clinical cases) versus those who were examined following genetic testing (Genetic cases).DESIGN: Retr
- PMID 27993484
- Sutureless Scleral Tunnel Trabeculectomy: Evaluation of Feasibility and Effectiveness versus Conventional Trabeculectomy for Management of Primary Open Angle Glaucoma.
- Khairy HA1, Elsawy MF1, Said-Ahmed K1.
- Seminars in ophthalmology.Semin Ophthalmol.2016 Dec 14:1-6. [Epub ahead of print]
- PURPOSE: To evaluate the intraocular pressure-lowering effect of sutureless scleral tunnel trabeculectomy with Mitomycin-C (MMC) compared to the standard trabeculectomy with MMC in patients with primary open angle glaucoma (POAG).METHODS: This was a masked, randomized, controlled comparison trial in
- PMID 27960578
Japanese Journal
- 臨床研究 広義の原発開放隅角緑内障患者に対する自動静的視野検査直後の冬期における一過性眼圧上昇
- 緑内障研究の進歩 : 原発開放隅角緑内障(広義)への挑戦-臨床的諸問題とその科学的解決-
- 杉山 和久,東出 朋巳,大久保 真司,新田 耕治,武田 久,奥田 徹彦,桜井 真由美,長田 敦,斎藤 代志明,高橋 真美,前田 有,辻屋 壮介,室谷 英治,若林 祐佳,高 延琳,中谷 雄介,馬渡 嘉郎,川口 一朗,川口 千晶,岡村 均,可児 一孝,樋田 一徳,岩瀬 愛子,川瀬 和秀,兼子 博章,福平 由佳子
- 日本眼科學会雜誌 116(3), 233-268, 2012-03-10
- … Primary open-angle glaucoma (POAG), including normal-tension glaucoma (NTG), is reported by the Tajimi Study to afflict 3.9% of the total population, and this represents about 80% of all total glaucoma cases which, in total, afflict 5.0% of the population. … We tried to analyze the clinical problems relating to POAG by looking at the pathogenesis, intraocular pressure (IOP), therapy, neuroprotection and surgery of the disease. …
- NAID 10030249484
- Use of microperimetry to compare macular light sensitivity in eyes with open-angle and angle-closure glaucoma
- Huang Ping,Shi Yan,Wang Xin [他],ZHANG Samuel Shao-Min,ZHANG Chun
- Japanese journal of ophthalmology 56(2), 138-144, 2012-03-01
- NAID 10030248677
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- 英
- primary open-angle glaucoma, POAG
- 同
- 原発性開放隅角緑内障、慢性単性緑内障 chronic simple glaucoma
- 関
- 緑内障
リスクファクター
- 年齢、黒人、家族歴、眼圧、その他(近視、偽落屑、拡張期低灌流圧(low diastolic perfusion pressure), 心血管疾患、高血圧([[systemic hypertension)、糖尿病、甲状腺機能低下症)
病態
- 前眼房は正常であるが、視神経乳頭や視野に緑内障性視神経症の所見が認められる。
- 初期には乳頭から耳上側、耳下側に弓状、楔状のやや暗赤色に見える部分が出現し、その部分お神経線維が消失し網膜神経線維層欠損を来す。これにより視野欠損(傍中心暗点、ザイデル暗点、ブエルム暗点)が認められるようになる。
症状
- 両側性に発症
- 初期には症状なく、視野狭窄が初発症状となる。
- 疼痛(眼痛)、充血は認められない。
検査
- 緑内障性の変化：傍中心暗点 → Seidel暗点 → Bjerrum暗点 → Roenne鼻側階段 → 中心視野のみreserve
参考
- http://www.nichigan.or.jp/member/guideline/glaucoma2.jsp
- 2. [charged] Open-angle glaucoma: Epidemiology, clinical presentation, and diagnosis - uptodate [1]
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