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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/07/05 00:23:01」(JST)
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Mycobacterium genavense |
Scientific classification |
Kingdom: |
Bacteria |
Phylum: |
Actinobacteria |
Order: |
Actinomycetales |
Suborder: |
Corynebacterineae |
Family: |
Mycobacteriaceae |
Genus: |
Mycobacterium |
Species: |
M. genavense |
Binomial name |
Mycobacterium genavense
Böttger et al. 1993, ATCC 51234 |
Mycobacterium genavense is a slow-growing species of the phylum actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus mycobacterium.
Contents
- 1 Description
- 2 Pathogenesis
- 3 Type strain
- 4 References
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Description[edit]
Nonmotile, acid-fast coccobacilli (1.0 µm x 2.0 µm). No formation of spores, capsules or aerial hyphae.
Colony characteristics
- Tiny, transparent, nonphotochromogenic and dysgonic colonies (on solid Middlebrook 7H11 medium MJ (Allied Laboratories).
Physiology
- Slow, fastidious growth in liquid media within 3–12 weeks at 31°C, 37°C and 42°C, with slightly better growth at 45°C.
- Primary cultures for isolation require liquid broth media such as BACTEC 12B medium, Middlebrook 7H9 medium.
- Acid broth media such as, BACTEC pyrazinamidase test medium, may facilitate primary isolation.
- No growth on standard solid media like Löwenstein-Jensen, unsupplemented Middlebrook 7H11 or Middlebrook 7H10 media.
- Visible growth on solid Middlebrook 7H11 medium supplemented with MJ after inoculation with a broth culture within 3–9 weeks.
- Susceptible to streptomycin and rifampicin
- Resistant to isoniazid and ethambutol
Differential characteristics
- Differentiation from other slowly growing mycobacteria by its fastidious growth.
- Closely related to M. simiae by evaluation of 16S rDNA sequences.
Pathogenesis[edit]
- Opportunistic pathogen. Clinically indistinguishable from generalised infections in patients with AIDS due to M. avium complex strains, but more related to gastro-intestinal disorders.
- Most common cause of mycobacterial disease in parrots and parakeets.
Type strain[edit]
Strain 2289 = ATCC 51234
References[edit]
- Böttger et al. 1993. Mycobacterium genavense sp. nov. Int. J. Syst. Bacteriol., 43, 841-843.
Mycobacteria (including Nontuberculous)
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Slowly growing
(R1P=photochromogenic;
R2S=scotochromogenic;
R3N=nonchromogenic) |
Long helix 18
(TKHGC)
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M. tuberculosis group
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- MTC
- M. tuberculosis
- M. bovis
- M. africanum
- M. microti
- M. canetti
- M. caprae
- M. pinnipedii
- MPM
- R1P
- M. marinum
- R2S
- M. pseudoshottsii
- R3N
- M. ulcerans
- M. shottsii
- M. liflandii
- Leprosy
- M. leprae
- M. lepraemurium
- M. lepromatosis
- R3N
- other
- M. lacus
- M. kumamotonense
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|
K/H groups
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M. kansasii group
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- MAC
- R3N
- M. intracellulare/M. avium
- M. avium subspecies paratuberculosis
- M. chimaera
- R2S
- M. bohemicum
- GK
- R1P
- M. kansasii
- R3N
- M. gastri
- R2S
- M. nebraskense
- M. seoulense
- R3N
- M. scrofulaceum
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M. haemophilum group
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M. gordonae group
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M. conspicuum group
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Long helix 18
(other)
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M. xenopi group
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- M. botniense
- M. shimoidei/M. xenopi
- M. heckeshornense
- M. hassiacum
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M. celatum group
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M. hiberniae group
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- M. terrae
- M. hiberniae
- M. nonchromogenicum/M. arupense
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Short helix 18
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M. simiae clade
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- M. simiae group
- R3N
- M. genavense/M. triplex
- M. florentinum/M. montefiorense
- M. heidelbergense/M. parmense
- M. simiae
- R2S
- M. lentiflavum
- M. kubicae group
- R3N
- M. parascrofulaceum
- R2S
- M. palustre/M. kubicae
- M. interjectum group
- M. interjectum
- M. saskatchewanense
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M. intermedium group
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Ungrouped
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- M. triviale
- M. doricum
- M. tusciae
- M. arosiense
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Rapidly growing/
Runyon IV |
M. neoaurum group
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- M. mageritense
- M. wolinskyi
- M. canariasense
- M. cosmeticum
- M. diernhoferi
- M. hodleri
- M. frederiksbergense
- M. neoaurum
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F/T groups
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M. fortuitum group
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- M. chitae/M. fallax/M. gadium
- M. rhodesiae
- M. houstonense
- M. neworleansense/M. boenickei/M. fortuitum/M. porcinum/M. senegalense
- M. septicum/M. peregrinum/M. alvei
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M. vaccae group
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- M. obuense/M. gilvum/M. parafortuitum
- M. chlorophenolicum/M. chubuense
- M. psychrotolerans/M. sphagni
- M. aubagnense/M. mucogenicum/M. phocaicum
- AV
- M. aurum
- M. vanbaalenii
- M. vaccae
- M. austroafricanum
- M. pyrenivorans
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M. smegmatis group
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- M. agri/M. thermoresistibile
- M. duvalii/M. flavescens
- M. monacense
- M. pulveris/M. conceptionense/M. moriokaense
- M. novocastrense/M. brumae/M. phlei
- M. confluentis/M. madagascariense
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M. chelonae group
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- M. komossense
- M. murale/M. tokaiense
- M. aichiense
- M. chelonae
- M. abscessus
- M. immunogenum
- M. massiliense
- M. bolletii
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M. elephantis group
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- M. elephantis
- M. holsaticum
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UpToDate Contents
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English Journal
- Disseminated Mycobacterium genavense infection in a chinchilla (Chinchilla lanigera).
- Huynh M1, Pingret JL2, Nicolier A3.
- Journal of comparative pathology.J Comp Pathol.2014 Jul;151(1):122-5. doi: 10.1016/j.jcpa.2014.03.003. Epub 2014 Mar 14.
- A 1-year-old neutered male chinchilla (Chinchilla lanigera) was presented with emaciation and a 1-month history of progressive weight loss. The animal was bright and responsive on clinical examination, but had poor body condition. Serum biochemical analysis revealed elevated alanine amino transferas
- PMID 24813153
- Disseminated Mycobacterium genavense infection in a patient with immunosuppressive therapy and lymphoproliferative malignancy.
- Numbi N, Demeure F, Van Bleyenbergh P, De Visscher N.
- Acta clinica Belgica.Acta Clin Belg.2014 Apr;69(2):142-5. doi: 10.1179/0001551213Z.00000000016.
- We present the case of a 51-year-old woman who presented a right supraclavicular mass corresponding to lymphadenitis with atypical mycobacterium (Mycobacterium genavense). Later, she developed subcutaneous purulent small nodules containing the same germ. The presence of this mycobacterium was in the
- PMID 24724760
Japanese Journal
- AIDS患者における播種性非結核性抗酸菌症 (Mycobacterium genavense) の1例
- 新野 大介,松木 啓,田中 健之,柳原 克紀,大楠 清文,林 徳真吉,今泉 芳孝,宮崎 泰司,有吉 紅也,大島 孝一
- 診断病理 : Japanese journal of diagnostic pathology 28(1), 18-20, 2011-01-31
- NAID 10028288045
- 症例報告 原発性免疫不全症患者に合併したMycobacterium genavense感染による多発脳病変の1例
Related Links
- Mycobacterium genavense is a slow-growing species of the phylum actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus mycobacterium .
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参考
- http://www.jata.or.jp/rit/rj/319kataki10.pdf#search='%E8%BF%85%E9%80%9F%E7%99%BA%E8%82%B2%E7%BE%A4+rapid+group'
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