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- Mycobacterium abscessus
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WordNet
- symptom consisting of a localized collection of pus surrounded by inflamed tissue
PrepTutorEJDIC
- 膿瘍(のうよう)(うんだできもの)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/05/31 05:10:44」(JST)
[Wiki en表示]
| Mycobacterium abscessus |
| Scientific classification |
| Kingdom: |
Bacteria |
| Phylum: |
Actinobacteria |
| Order: |
Actinomycetales |
| Suborder: |
Corynebacterineae |
| Family: |
Mycobacteriaceae |
| Genus: |
Mycobacterium |
| Species: |
M. abscessus |
| Binomial name |
Mycobacterium abscessus
Kusonoki and Ezaki 1992 ATCC 19977 |
Mycobacterium abscessus is a rapidly growing mycobacterium that is a common water contaminant. It was until recently (1992) thought to be a subspecies of Mycobacterium chelonae. M. abscessus can cause chronic lung disease, post-traumatic wound infections, and disseminated cutaneous diseases, mostly in patients with suppressed immune systems.
It is classified as a rapid growing mycobacterium.[1]
M. abscessus grown in starch-based medium on a petri dish. Colonies appear as light yellow streaks.
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Contents
- 1 Description
- 2 Physiology
- 3 Differential characteristics
- 4 Pathogenesis
- 5 Type strain
- 6 References
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Description [edit]
M. abscessus cells are Gram-positive, nonmotile, acid-fast rods of about 1.0 - 2.5 µm long by 0.5 µm wide. They may form colonies on Löwenstein-Jensen media that appear smooth or rough, white or greyish and nonphotochromogenic.
Physiology [edit]
M. abscessus shows growth at 28°C and 37°C after 7 days but not at 43°C. It may grow on MacConkey agar at 28°C and even 37°C. It shows tolerance to saline media (5% NaCl) as well as 500 mg/l hydroxylamine (Ogawa egg medium) and 0.2% picrate (Sauton agar medium). Strains of the species have been shown to degrade the antibiotic p-aminosalicylate. M. abscessus has also been shown to produce arylsulfatase but not of nitrate reductase and Tween 80 hydrolase. It shows a negative result for the iron uptake test and no utilisation of fructose, glucose, oxalate or citrate as sole carbon sources.
Differential characteristics [edit]
M. abscessus and M. chelonae can be distinguished from M. fortuitum or M. peregrinum by their failure to reduce nitrate and to take up iron. Tolerance to 5% NaCl in Löwenstein-Jensen media, tolerance to 0.2% picrate in Sauton agar, and non-utilisation of citrate as a sole carbon source are characteristics that distinguish M. abscessus from M. chelonae. M. abscessus and M. chelonae sequevar I share an identical sequence in the 54-510 region of 16S rRNA, though both species can be differentiated by their hsp65, ITS or rpoB gene sequences.
Pathogenesis [edit]
M. abscessus may cause chronic lung disease, post-traumatic wound infections, and skin infections in immunodeficient patients.
It can be associated with middle ear infections (otitis media).[2]
Type strain [edit]
ATCC 19977 = CCUG 20993 = CIP 104536 = DSM 44196 = JCM 13569 = NCTC 13031
References [edit]
- ^ Esteban J, Ortiz-Pérez A (December 2009). "Current treatment of atypical mycobacteriosis". Expert Opin Pharmacother 10 (17): 2787–99. doi:10.1517/14656560903369363. PMID 19929702.
- ^ Linmans JJ, Stokroos RJ, Linssen CF (September 2008). "Mycobacterium abscessus, an uncommon cause of chronic otitis media: a case report and literature review". Arch. Otolaryngol. Head Neck Surg. 134 (9): 1004–6. doi:10.1001/archotol.134.9.1004. PMID 18794448.
- Kusunoki,S.,T. Ezaki. 1992. Proposal of Mycobacterium peregrinum sp. nov., nom. rev., and elevation of Mycobacterium chelonae subsp. abscessus (Kubica et al.) to species status: Mycobacterium abscessus comb. nov. Int. J. Syst. Bacteriol. 42, 240-245.
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Mycobacteria (including Nontuberculous)
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Slowly growing
(R1P=photochromogenic;
R2S=scotochromogenic;
R3N=nonchromogenic) |
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Long helix 18
(TKHGC)
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M. tuberculosis group
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- MTC
- M. tuberculosis
- M. bovis
- M. africanum
- M. microti
- M. canetti
- M. caprae
- M. pinnipedii
- MPM
- R1P
- M. marinum
- R2S
- M. pseudoshottsii
- R3N
- M. ulcerans
- M. shottsii
- M. liflandii
- Leprosy
- M. leprae
- M. lepraemurium
- M. lepromatosis
- R3N
- other
- M. lacus
- M. kumamotonense
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K/H groups
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M. kansasii group
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- MAC
- R3N
- M. intracellulare/M. avium
- M. avium subspecies paratuberculosis
- M. chimaera
- R2S
- M. bohemicum
- GK
- R1P
- M. kansasii
- R3N
- M. gastri
- R2S
- M. nebraskense
- M. seoulense
- R3N
- M. scrofulaceum
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M. haemophilum group
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M. gordonae group
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M. conspicuum group
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Long helix 18
(other)
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M. xenopi group
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- M. botniense
- M. shimoidei/M. xenopi
- M. heckeshornense
- M. hassiacum
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M. celatum group
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M. hiberniae group
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- M. terrae
- M. hiberniae
- M. nonchromogenicum/M. arupense
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Short helix 18
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M. simiae clade
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- M. simiae group
- R3N
- M. genavense/M. triplex
- M. florentinum/M. montefiorense
- M. heidelbergense/M. parmense
- M. simiae
- R2S
- M. lentiflavum
- M. kubicae group
- R3N
- M. parascrofulaceum
- R2S
- M. palustre/M. kubicae
- M. interjectum group
- M. interjectum
- M. saskatchewanense
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M. intermedium group
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Ungrouped
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- M. triviale
- M. doricum
- M. tusciae
- M. arosiense
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Rapidly growing/
Runyon IV |
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M. neoaurum group
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- M. mageritense
- M. wolinskyi
- M. canariasense
- M. cosmeticum
- M. diernhoferi
- M. hodleri
- M. frederiksbergense
- M. neoaurum
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F/T groups
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M. fortuitum group
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- M. chitae/M. fallax/M. gadium
- M. rhodesiae
- M. houstonense
- M. neworleansense/M. boenickei/M. fortuitum/M. porcinum/M. senegalense
- M. septicum/M. peregrinum/M. alvei
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M. vaccae group
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- M. obuense/M. gilvum/M. parafortuitum
- M. chlorophenolicum/M. chubuense
- M. psychrotolerans/M. sphagni
- M. aubagnense/M. mucogenicum/M. phocaicum
- AV
- M. aurum
- M. vanbaalenii
- M. vaccae
- M. austroafricanum
- M. pyrenivorans
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M. smegmatis group
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- M. agri/M. thermoresistibile
- M. duvalii/M. flavescens
- M. monacense
- M. pulveris/M. conceptionense/M. moriokaense
- M. novocastrense/M. brumae/M. phlei
- M. confluentis/M. madagascariense
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M. chelonae group
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- M. komossense
- M. murale/M. tokaiense
- M. aichiense
- M. chelonae
- M. abscessus
- M. immunogenum
- M. massiliense
- M. bolletii
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M. elephantis group
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- M. elephantis
- M. holsaticum
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Actinobacteria (high-G+C) Infectious diseases · Bacterial diseases: G+ (primarily A00–A79, 001–041, 080–109)
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| Actinomycineae |
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Actinomycetaceae
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Actinomyces israelii (Actinomycosis, Cutaneous actinomycosis) · Tropheryma whipplei (Whipple's disease) · Arcanobacterium haemolyticum (Arcanobacterium haemolyticum infection) · Actinomyces gerencseriae
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Propionibacteriaceae
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Propionibacterium acnes
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| Corynebacterineae |
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Mycobacteriaceae
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M. tuberculosis/
M. bovis
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Tuberculosis: Ghon focus/Ghon's complex · Pott disease · brain (Meningitis, Rich focus) · Tuberculous lymphadenitis (Tuberculous cervical lymphadenitis) · cutaneous (Scrofuloderma, Erythema induratum, Lupus vulgaris, Prosector's wart, Tuberculosis cutis orificialis, Tuberculous cellulitis, Tuberculous gumma) · Lichen scrofulosorum · Tuberculid (Papulonecrotic tuberculid) · Primary inoculation tuberculosis · Miliary · Tuberculous pericarditis · Urogenital tuberculosis · Multi-drug-resistant tuberculosis · Extensively drug-resistant tuberculosis
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M. leprae
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Leprosy: Tuberculoid leprosy · Borderline tuberculoid leprosy · Borderline leprosy · Borderline lepromatous leprosy · Lepromatous leprosy · Histoid leprosy
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Nontuberculous
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R1: M. kansasii · M. marinum (Aquarium granuloma)
R2: M. gordonae
R3: M. avium complex/Mycobacterium avium/Mycobacterium intracellulare/MAP (MAI infection) · M. ulcerans (Buruli ulcer) · M. haemophilum
R4/RG: M. fortuitum · M. chelonae · M. abscessus
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Nocardiaceae
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Nocardia asteroides/Nocardia brasiliensis (Nocardiosis) · Rhodococcus equi
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Corynebacteriaceae
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Corynebacterium diphtheriae (Diphtheria) · Corynebacterium minutissimum (Erythrasma) · Corynebacterium jeikeium (Group JK corynebacterium sepsis)
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| Bifidobacteriaceae |
Gardnerella vaginalis
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gr+f/gr+a (t)/gr-p (c)/gr-o
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drug (J1p, w, n, m, vacc)
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UpToDate Contents
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English Journal
- Identification of antimicrobial activity among FDA-approved drugs for combating Mycobacterium abscessus and Mycobacterium chelonae.
- Chopra S, Matsuyama K, Hutson C, Madrid P.SourceCenter for Infectious Disease and Biodefense Research, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA.
- The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2011 Jul;66(7):1533-6. Epub 2011 Apr 11.
- Objectives Rapidly growing mycobacteria have long been neglected in drug discovery efforts and this neglect is reflected in the paucity of therapeutic options available for diseases resulting from these infections. The purpose of this work is to identify new candidate drugs for treating non-tubercul
- PMID 21486854
Japanese Journal
- 肺切除術にて根治可能であった Mycobacterium abscessus 肺感染症の一例
- 岩田 輝男,井上 政昭,岩浪 崇嗣,森山 裕之,川口 誠,安元 公正
- 日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 24(7), 1055-1059, 2010-11-15
- … 胸水貯留にて発症し，診断に難渋したMycobacterium abscessus（M. …
- NAID 10026963697
Related Links
- 1 Mycobacterium abscessus肺感染症の臨床的検討 小橋 吉博 岡 三喜男 要旨：〔目的〕Mycobacterium abscessusによる肺感染症の臨床像を検討した。〔対象と方法〕対象は，当院および関連施設において最近5年間にM ...
- Mycobacterium abscessus is a rapidly growing mycobacterium that is a common water contaminant. It was until recently (1992) thought to be a subspecies of Mycobacterium chelonae. M. abscessus can cause chronic lung disease ...
- Mycobacterium abscessus answers are found in the Johns Hopkins Antibiotic (ABX) Guide -- online and for download to iPhone, iPad, Android, BlackBerry, and Window Phone. ... MICROBIOLOGY Human pathogen, occasional ...
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参考
- http://www.jata.or.jp/rit/rj/319kataki10.pdf#search='%E8%BF%85%E9%80%9F%E7%99%BA%E8%82%B2%E7%BE%A4+rapid+group'
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