WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
the 9th letter of the Roman alphabet (同)i
(psychoanalysis) primitive instincts and energies underlying all psychic activity
a card or badge used to identify the bearer; "you had to show your ID in order to get in" (同)I.D.

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1. 知的障害（精神遅滞）をもつ成人のプライマリケア primary care of the adult with intellectual disability mental retardation
2. 小児における知的障害（精神遅滞）：原因の評価 intellectual disability mental retardation in children evaluation for a cause
3. 小児における知的障害（精神遅滞）：管理、転帰および予防 intellectual disability mental retardation in children management outcomes and prevention
4. 小児における知的障害（精神遅滞）：定義、診断、およびニーズの評価 intellectual disability mental retardation in children definition diagnosis and assessment of needs
5. フェニルケトン尿症の概要 overview of phenylketonuria

SILAC based protein profiling data of MKK3 knockout mouse embryonic fibroblasts.

Srivastava A1, Shinn AS1, Lam TT2, Lee PJ1, Mannam P1.
Data in brief.Data Brief.2016 Mar 2;7:418-22. doi: 10.1016/j.dib.2016.02.034. eCollection 2016.
This data article reports changes in the phospho and total proteome of MKK3 knock out (MKK3(-) (/) (-)) mouse embryonic fibroblasts (MEFs). The dataset generated highlights the changes at protein level which can be helpful for understanding targets of the MAP kinase signaling pathway. Data was colle
PMID 26977448

KCNQ1 gene variants in the risk for type 2 diabetes and impaired renal function in the Spanish Renastur cohort.

Riobello C1, Gómez J1, Gil-Peña H2, Tranche S3, Reguero JR4, de la Hera JM4, Delgado E5, Calvo D4, Morís C6, Santos F7, Coto-Segura P8, Iglesias S1, Alonso B1, Alvarez V1, Coto E9.
Molecular and cellular endocrinology.Mol Cell Endocrinol.2016 May 15;427:86-91. doi: 10.1016/j.mce.2016.03.007. Epub 2016 Mar 9.
Several common KCNQ1 gene polymorphisms have been associated with the risk of type 2 diabetes (T2DM) and diabetic nephropathy. This effect is explained by the role of the kcnq1 protein as a potassium channel that in the pancreatic beta-cells drives an electrical signal that facilitates glucose-stimu
PMID 26970180

A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review.

Merner N1,2,3, Forgeot d'Arc B4, Bell SC1,5, Maussion G1,5, Peng H5, Gauthier J6, Crapper L1, Hamdan FF6, Michaud JL6, Mottron L4, Rouleau GA1,2,3, Ernst C1,2,5,7.
American journal of medical genetics. Part A.Am J Med Genet A.2016 May;170(5):1225-35. doi: 10.1002/ajmg.a.37566. Epub 2016 Jan 20.
Mutations in chromodomain helicase DNA-binding domain 8 (CHD8) have been identified in independent genotyping studies of autism spectrum disorder. To better understand the phenotype associated with CHD8 mutations, we genotyped all CHD8 exons in carefully assessed cohorts of autism (n = 142), sch
PMID 26789910

川島秀一,岡本忍,金久實
情報処理学会研究報告. BIO, バイオ情報学 2011-BIO-24(13), 1-2, 2011-03-03
… Indexingは,学術論文全文から遺伝子情報を人手により抽出したデータであり,主にシアノバクテリアについて,18万件の,遺伝子IDと記載場所の情報(題名,導入,手法,結果,考察等)が対応づけられたレコードが蓄積されている.本発表では,このデータを利用して,論文中の各セクションに共起する遺伝子ペアが,同じパスウェイやタンパク質複合体上に存在する割合や,同じタンパク質ドメインを持つ割合を調査し,記述されるセク …
NAID 110008584218

Induction of Differentiation by Panaxydol in Human Hepatocarcinoma SMMC-7721 Cells via cAMP and MAP Kinase Dependent Mechanism

WANG Ze-Jian,SONG Li,GUO Lin-Chen,YIN Min,SUN Yong Ning
YAKUGAKU ZASSHI 131(6), 993-1000, 2011
… The expression of p-ERK, Id1, and p21 were determined by Western blot. … These changes of differentiation markers in SMMC-7721 can be reversed by the protein kinase A inhibitor RpcAMPS and by MAP kinase kinase 1/2 inhibitor U0126 or sorafenib. … Panaxydol dose-dependently decreased the expression of regulatory factors Id1 and increased the protein levels of p21 and p-ERK1/2 correspondingly. …
NAID 130000926986