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1. 白血球粘着不全症 leukocyte adhesion deficiency
2. 炎症の病因における白血球内皮細胞接着 leukocyte endothelial adhesion in the pathogenesis of inflammation
3. マンノース結合レクチン mannose binding lectin
4. 血液-血液透析膜の相互作用に関与する生化学的機序 biochemical mechanisms involved in blood hemodialysis membrane interactions
5. コレラ菌感染の病因 pathogenesis of vibrio cholerae infection

N-Glycosylations of human α1,3-fucosyltransferase IX are required for full enzyme activity.

Seelhorst K, Stacke C, Ziegelmüller P, Hahn U.SourceHamburg University, MIN-Faculty, Department of Chemistry, Institute of Biochemistry and Molecular Biology, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
Glycobiology.Glycobiology.2012 Dec 21. [Epub ahead of print]
Human α1,3-fucosyltransferase IX catalyzes the transfer of L-fucose from GDP-β-L-Fucose to N-acetyllactosamine, generating a Lewis X epitope, and is thereby involved in the synthesis of fucosylated cell surface glycoconjugates. It contains three putative N-glycosylation sites (Asn62, Asn101 and As
PMID 23263199

Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8).

Kötzler MP, Blank S, Bantleon FI, Spillner E, Meyer B.SourceInstitute of Organic Chemistry, University of Hamburg, Germany.
Biochimica et biophysica acta.Biochim Biophys Acta.2012 Dec;1820(12):1915-25. doi: 10.1016/j.bbagen.2012.08.018. Epub 2012 Sep 7.
BACKGROUND: Fucosylation is essential for various biological processes including tumorigenesis, inflammation, cell-cell recognition and host-pathogen interactions. Biosynthesis of fucosylated glycans is accomplished by fucosyltransferases. The enzymatic product of core α1,6-fucosyltransferase (FUT8
PMID 22982178

Decrease in Antithrombin III Fucosylation by Expressing GDP-fucose Transporter siRNA in Chinese Hamster Ovary Cells(CELL AND TISSUE ENGINEERING)

Omasa Takeshi,Tanaka Ryo,Doi Tomohiro,Ando Masayuki,Kitamoto Yuka,Honda Kohsuke,Kishimoto Michimasa,Ohtake Hisao
Journal of bioscience and bioengineering 106(2), 168-173, 2008-08-25
… The full-length cDNA of GDP-fucose transporter (GFT) was cloned from Chinese hamster ovary (CHO) 13D-35D cells. … CHO cells, which were transfected with the siRNA expression plasmid, showed approximately 75% reduction of Golgi-GDP fucose, resulting in 10-40% increase in defucosylated AT-III. …
NAID 110006873806